Games like Mainframe Defenders

"Star Renegades" is a tactical rogue-lite RPG with a procedurally generated campaign and a reactive battle system. Fight against the Imperial army using interrupts and counters, while facing off against an adaptive Adversary system. As heroes fall, recruit new ones and continue the battle to resist and reclaim.

Into the Breach is a turn-based strategy game where players defend Earth from an alien invasion. Command powerful mechs to protect cities and defeat the Vek threat in this tactical battlefield. Each decision matters as failed missions can result in global consequences, and only the most strategic pilots will ensure humanity's survival.

Pathway is a single-player Warfare Turn Based Strategy game with an interesting plot, good game mechanics, stellar graphics, and an exceptional soundtrack. The game now features a Hardcore Mode, tactical improvements, a new loot system, additional combat arenas, and more exploration opportunities with the Adventurers Wanted update. Despite having some bugs and being very grinding, Pathway offers plenty of humor, a dense atmosphere, and high replayability.

"The Last Spell" is a turn-based tactical RPG with roguelite elements, where you must defend a city from hordes of enemies over consecutive nights. During the day, strategize by building defenses, leveling up heroes, and choosing skills and weapons. Overcome challenges, break the magic seal, and banish all magic from the world. Experience a range of stats, skills, perks, and traits for a deep RPG experience.

Warhammer 40,000: Mechanicus is a turn-based strategy game that puts you in charge of the Adeptus Mechanicus, an elite army of the Imperium, on a mission to explore a recently discovered Necron planet. The game offers a unique blend of religious and technological themes, with an emphasis on customization and strategy. The Omnissiah Edition includes bonus content such as a soundtrack, digital artbook, and a short story.

Metal Slug Tactics is a tactical RPG that combines the classic, arcade action of the Metal Slug series with roguelike elements. Assemble your team of iconic brothers-in-arms and lead them to victory through strategic battles, unlocking new weapons and skills as you go. Experience the nostalgic charm of Metal Slug in a whole new way!

SteamWorld Heist is a single-player Science Fiction Turn Based Strategy game with a sensational story and splendid gameplay, featuring outstanding visuals and music. As Captain Piper Faraday, you'll recruit a crew of steam-driven robots, board and loot enemy spaceships, and upgrade your robots with unique abilities and weapons in a very replayable game with a unique atmosphere and lots of grinding. Join the adventure in the vast frontier and collect stylish hats!

"Mech Armada is a single-player Warfare Turn Based Strategy game, offering around 17 hours of playtime with no two runs being the same. Command your own team of custom-built Mechs, upgrading from over 80 unique parts, in deep grid-based combat against The Swarm's bosses. Procedurally generated levels with varied post-apocalyptic environments create a challenging and engaging experience."

"Halfway" is a single-player Science Fiction Turn Based Strategy game with an intriguing story and good gameplay. As the leader of a team of survivors, you must fight and outsmart the enemy aboard a colonized spaceship while uncovering the mysteries of the violent invasion. The game features tactical turn-based battles, unique characters, and an immersive storyline with outstanding visuals and fantastic music, though some grinding is required.

"Shardpunk is a single-player Turn Based Strategy game with delightful mechanics, set in a unique steampunk Victorian atmosphere. Outrun relentless hordes, seek shelter, and manage resources to survive. Tactical gameplay and RPG elements combine for challenging decisions and gripping survival."