Skip to main content
Games like Isolate ME!

Games like Isolate ME!

Games like Isolate ME!

Looking for games like Isolate ME!? Here are top survival simulation recommendations, selected from player-similarity data — start with Super Sanctum TD, Quarantine or Infectonator 3: Apocalypse.

Change display type

Skip Platform filter

Skip Play Mode filter

Skip Price filter
  1. 83%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:story, grinding
    83% User Score Based on 861 reviews

    Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core! When the aliens swarm your maze and everything seems lost, use active abilities like Air Strike and Freeze to tilt the battlefield to your advantage. If you enjoyed this game, see our list of games similar to Super Sanctum TD.

    View Game
  2. View Game
  3. 79%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding, replayability
    79% User Score Based on 690 reviews
    Critic Score 80%Based on 1 reviews

    A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding. If you enjoyed this game, see our list of games similar to Infectonator 3: Apocalypse.

    View Game
  4. 76%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, grinding
    76% User Score Based on 127 reviews
    Critic Score 75%Based on 2 reviews

    FIGHT IN EVER CHANGING SPACE BATTLES! Run through the universe, discover the numerous perks/consumables and their synergistic effects. Explore the randomly-generated galaxy to find merchants,... If you enjoyed this game, see our list of games similar to Stellar Interface.

    View Game
  5. View Game
    79%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:stability, grinding
    80% User Score Based on 61 reviews
    Critic Score 76%Based on 3 reviews

    Elsie is an indie action-platformer filled with rogue-like mechanics such as perma-death, procedurally generated levels, and a wide scope of items and weaponry to make each run as unique as possible. If you enjoyed this game, see our list of games similar to Elsie.

    View Game
  6. View Game
  7. View Game
    53%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:graphics, music
    53% User Score Based on 135 reviews

    Metrocide is a relentless top-down single-player arcade stealth-shooter set in a cyberpunk dystopia where everyone wants you dead. As legendary contract killer T.J. Trench, you’ll have to negotiate a fierce and brutal city replete with gangs, vigilantes, cops and more, taking out the trash one contract at a time. While cop drones circle overhead, you’ll be sticking to the alleyways with a variety… If you enjoyed this game, see our list of games similar to Metrocide.

    View Game
  8. 70%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:replayability, story
    93% User Score Based on 27 reviews

    You Died ... but a Necromancer revived you! Reaching the top is no easy feat: The pathways are narrow, full of traps and on top of that, the floor will start exploding behind you if you take too long! If you enjoyed this game, see our list of games similar to You Died but a Necromancer revived you.

    View Game
  9. View Game
  10. 71%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:replayability, stability
    71% User Score Based on 364 reviews
    Critic Score 70%Based on 2 reviews

    Squeeze into your toga and slide on your sandals to rally the angry mobs of Okhlos and bring down the oppressive god of mythological Greece! If you enjoyed this game, see our list of games similar to Okhlos: Omega.

    View Game
  11. Darkness invades the world, and the light of the entire continent is devoured. Somewhere in the world, the last magical lighthouse shines its final light. Guard it, for it is the last hope of this world! Meow Tower - Doomsguard is a game rich in roguelike elements. The instant changes and strategies during battles will determine whether you win or lose. It is a strategic RPG game that combines … If you enjoyed this game, see our list of games similar to Meow Tower - Doomsguard.

    View Game
  12. 74%Game Brain Score
    Most mentioned positive aspects:gameplay, atmosphere
    Most mentioned negative aspects:stability, graphics
    74% User Score Based on 250 reviews

    Roadmap About the Game Caution: This game is not recommended for those prone to airsickness!Have you ever wondered what else flight attendants do besides serving tea and coffee? If you’re curious, step into Cabin Crew Life Simulator and find out! Play as a stunning flight attendant and undergo intensive training to master every aspect of the job. From conducting safety checks and providi… If you enjoyed this game, see our list of games similar to Cabin Crew Life Simulator.

    View Game
  13. 83%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, optimization
    86% User Score Based on 2,230 reviews
    Critic Score 70%Based on 2 reviews

    Roguelike Deckbuilder where you use your cards to construct a hellish tower capable of keeping the endless hordes of the underworld from escaping their torment. If you enjoyed this game, see our list of games similar to Heretic's Fork.

    View Game
  14. View Game
    92%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    92% User Score Based on 935 reviews

    Rift Wizard is a tough as nails fantasy roguelike featuring challenging turn based combat and deep open ended character building. Craft your spellbook from over 100 unique spells and abilities and fight your way through a series of procedurally generated challenges to defeat your nemesis. If you enjoyed this game, see our list of games similar to Rift Wizard.

    View Game
  15. 78%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, optimization
    77% User Score Based on 462 reviews
    Critic Score 79%Based on 2 reviews

    Deadly Days is a unique strategic rogue-lite in the zombie apocalypse. Manage and protect a group of survivors and help them to stop the catastrophe. Discover and use a large number of wild and crazy objects, even wilder and crazier survivors, special abilities, and deadly weapons. If you enjoyed this game, see our list of games similar to Deadly Days.

    View Game
  16. View Game
    71%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:replayability
    73% User Score Based on 164 reviews
    Critic Score 65%Based on 1 reviews

    Ether Loop is a hardcore fast-paced bullet hell with roguelike elements. Descend the unforgiving depths of a mysterious world, encounter challenges, discover dynamic environments and fight ruthless creatures while unveiling the secrets of Ether Loop. If you enjoyed this game, see our list of games similar to Ether Loop.

    View Game
  17. 87%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, stability
    90% User Score Based on 1,732 reviews
    Critic Score 70%Based on 1 reviews

    Take command of your mercenary forces in Atom Zombie Smasher. The zombie apocalypse is upon us and it's up to you to evacuate everyone before they fall prey to the undead. If you enjoyed this game, see our list of games similar to Atom Zombie Smasher.

    View Game
  18. 59%Game Brain Score
    Most mentioned positive aspects:humor, replayability
    Most mentioned negative aspects:gameplay, stability
    59% User Score Based on 448 reviews

    The new version of Geopolitical Simulator 4, the ultrarealistic simulator of today's world where you play as the head of state or as the opposition! Stop the spread of the Covid-19 pandemic and restart the economy, participate in the US elections or engage in lightning wars with new 2020 scenarios. If you enjoyed this game, see our list of games similar to Power & Revolution 2020 Edition.

    View Game
  19. 87%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, stability
    87% User Score Based on 2,140 reviews

    A toxic waste spill finds its way into the water supply causing the recently deceased rise from their graves. Now you have to shoot your way through the hordes of undead to reach your only hope for survival. On the way to your rescue you will have to search stores and houses for supplies, and trade with other survivors. With three game modes, hundreds of items, weapons and grenades, and a city tha… If you enjoyed this game, see our list of games similar to Dead Pixels.

    View Game
  20. View Game
  21. 92%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, stability
    93% User Score Based on 6,164 reviews
    Critic Score 85%Based on 1 reviews

    Defend the last bastion of humanity with your squad of heroes! Exterminate fiendish monsters with magic and brute force by night and re-build your battered city defenses by day in this tactical RPG with rogue-lite mechanics. If you enjoyed this game, see our list of games similar to The Last Spell.

    View Game
  22. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:stability, grinding
    85% User Score Based on 9,352 reviews

    Dungeon of the Endless is a roguelike-like tower defense game. The player takes the role of survivors in a prison spaceship after its escape pods crash landed on a planet on their way to the Auriga system, which they were supposed to colonize as slaves. If you enjoyed this game, see our list of games similar to Dungeon of the Endless.

    View Game
  23. View Game
    84%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:optimization, grinding
    84% User Score Based on 578 reviews

    Fend off hordes of enemies in this arcade tower defense roguelite with autobattler elements. Build up a team of powerful synergies and become unstoppable. If you enjoyed this game, see our list of games similar to FLERP.

    View Game
  24. 96%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding, optimization
    96% User Score Based on 229 reviews

    Far Mining is a short and relaxing incremental game about mining asteroids. Mine resources, upgrade your ship, unlock new tools, and find your way out of deep space. If you enjoyed this game, see our list of games similar to Far Mining.

    View Game
  25. Explore, farm, and fight in Tales of Bloomrise! Enjoy a relaxing village life with fishing and crafting, and test your skills in procedural dungeons. A pixel art world that grows with every update, blending cozy vibes with intense action combat. If you enjoyed this game, see our list of games similar to Tales of Bloomrise.

    View Game
  26. 41%Game Brain Score
    Most mentioned positive aspects:graphics, replayability
    Most mentioned negative aspects:gameplay
    70% User Score Based on 10 reviews

    Hopeless Sea begins in the late stages of a climatic apocalypse—triggered by the domino effect of global warming, which caused a sudden and drastic rise in global temperatures, leading to the massive melting of polar ice caps. By the mid-21st century, nearly all polar ice had vanished, resulting in a global sea level rise of over 50 meters. This rendered 90% of the world’s coastal megacities uninh… If you enjoyed this game, see our list of games similar to Hopeless Sea.

    View Game
  27. 74%Game Brain Score
    Most mentioned positive aspects:gameplay, humor
    Most mentioned negative aspects:optimization, graphics
    74% User Score Based on 233 reviews

    A rich paragraph of information which will try to charm and pique interest, trying to catch your eye in a sea of competition using a slew of buzzwords such as ‘bullet heaven’ and ‘in-depth meta-progression’, in a vain attempt to make you believe this game is any different from others in it’s genre. If you enjoyed this game, see our list of games similar to RICE: Repetitive Indie Combat Experience.

    View Game
  28. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:optimization, graphics
    90% User Score Based on 128 reviews

    An array of diverse cluckmechs, each with its unique style, team up in bizarre and wondrous waysOver hundreds of defensive facilities, and this is just one tower defense gameplay? With over 300 different upgrade paths, tailored to players' own factions. Tower by tower, enhance by enhance, a myriad of combinations will trigger marvelous chemical reactions, offering infinite lineup possibilities! Di… If you enjoyed this game, see our list of games similar to Cluckmech Oasis.

    View Game
  29. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding
    95% User Score Based on 1,455 reviews

    Astro Prospector is an incremental bullet heaven about mining cofferoids and fighting SpaceCorp. Collect resources, upgrade your ship and become unstoppable. Return AstroCoffee to humanity! If you enjoyed this game, see our list of games similar to Astro Prospector.

    View Game
  30. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, story
    90% User Score Based on 1,033 reviews

    Become a martial arts master in this survivor-like roguelite inspired by action movies of the ‘80s. Use your fists, feet, and the environment to fight off relentless thugs. Master powerful combos, enhance your skills, and remember: everything around you is a weapon! If you enjoyed this game, see our list of games similar to Karate Survivor.

    View Game
  31. View Game
    86%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:graphics, grinding
    86% User Score Based on 85 reviews

    Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible! If you enjoyed this game, see our list of games similar to Lifecraft.

    View Game
  32. 71%Game Brain Score
    Most mentioned positive aspects:gameplay, humor
    Most mentioned negative aspects:story, grinding
    71% User Score Based on 340 reviews

    You’re being Bounty-Hunted! Run, Build your ship piece-by-piece and make it work with the parts you find, Destroy outposts and waves of fleets, and Pick your battles carefully to overcome your hunters in this Fast-Paced Top-Down Action Roguelite Shooter. If you enjoyed this game, see our list of games similar to Run Build Pew!.

    View Game
  33. 54%Game Brain Score
    Most mentioned negative aspects:gameplay, monetization
    68% User Score Based on 31 reviews

    Covid: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins! If you enjoyed this game, see our list of games similar to COVID: The Outbreak.

    View Game
  34. View Game
    64%Game Brain Score
    Most mentioned positive aspects:graphics, story
    Most mentioned negative aspects:gameplay, music
    64% User Score Based on 85 reviews

    You awaken to the dawn of a new world. It's streams are clean, the forests lush and the local wildlife is hungry. You're cold and in need of shelter as you hear other voices on the wind. You are not alone. Your quest: Establish civilization and secure their safety in this new world. Your Quest is a casual 2D Strategy/RPG with progressive gameplay where you gather resources to construct a vill… If you enjoyed this game, see our list of games similar to Your Quest.

    View Game
  35. 81%Game Brain Score
    Most mentioned positive aspects:story, graphics
    Most mentioned negative aspects:gameplay, replayability
    81% User Score Based on 167 reviews

    If you were given another chance, would you take it? Or leave it in the hands of a little girl? Play as Roh, a young girl stuck in a bizarre nightmare of dark and eerie creatures. If you enjoyed this game, see our list of games similar to Red Bow.

    View Game
  36. View Game
    91%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, replayability
    91% User Score Based on 86 reviews

    Amaranthine - is a dynamic horizontal scrolling shooter with procedurally generated elements. Travel through warp to the distant frozen planet send a distress signal. If you enjoyed this game, see our list of games similar to Amaranthine.

    View Game
  37. 84%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:grinding, stability
    84% User Score Based on 1,269 reviews

    ADOM (Ancient Domains Of Mystery) is one of the most successful roguelike games ever created, boasting a brilliant mix of story, RPG, exploration, and intensely strategic and flexible combat. The Steam version adds various Deluxe features like achievements, difficulty level customization and various play modes (e.g. a story mode allowing to save and restore games, a weekly challenge game, an explo… If you enjoyed this game, see our list of games similar to ADOM (Ancient Domains Of Mystery).

    View Game
  38. 83%Game Brain Score
    Most mentioned positive aspects:replayability
    Most mentioned negative aspects:story, graphics
    83% User Score Based on 80 reviews

    Play on randomly generated worlds with a party of characters just the way you like it. You will not be bounded by classes or scripted story, only by your creativity. Make your own journey. Tell your own history. If you enjoyed this game, see our list of games similar to Endless RPG.

    View Game
  39. 58%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:grinding, replayability
    54% User Score Based on 90 reviews
    Critic Score 65%Based on 6 reviews

    FIGHT OR DIE! Cursed by the evil Wizard King, bounty hunters Lea and Leo are chased by every monster in the kingdom and the Grim Reaper himself! There's only one way to get rid of the curse; the legendary Elixir of Life! But how to get the ingredients? FIGHT MONSTERS! If you enjoyed this game, see our list of games similar to Curses 'N Chaos.

    View Game
  40. 88%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, stability
    88% User Score Based on 64 reviews

    Planetary Dustoff is a moddable roguelite shooter. Go on a death riddled journey to sprawling alien environments and fight your way through hordes of enemies and epic boss battles. Unearth the many secrets of THE SPACE FACTION and find a new home for humanity. If you enjoyed this game, see our list of games similar to Planetary Dustoff.

    View Game
  41. 86%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:replayability, story
    87% User Score Based on 112 reviews
    Critic Score 80%Based on 1 reviews

    Endhall is a byte-sized roguelike. Become an artificial intelligence and combine tactical actions to defeat your enemies and reach the end of the hallway. If you enjoyed this game, see our list of games similar to Endhall.

    View Game
  42. 76%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding
    76% User Score Based on 74 reviews

    Attempt to out-maneuver and out-gun waves of enemies with different stats, abilities, and behaviors Robot Resistors 1.0 has 17 playable characters, 5 complete levels and a vast array of unlockable weapons and upgrades. Confront challenging bosses with unique designs and movesets Explore strange and exotic locales and get a glimpse of the dark future that awaits robot-kind should you fail. Each pr… If you enjoyed this game, see our list of games similar to Robot Resistors.

    View Game
  43. 84%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:stability, grinding
    93% User Score Based on 21,246 reviews
    Critic Score 73%Based on 8 reviews

    Risk of Rain is an action platformer with roguelike elements. With permanent death as a primary feature, players will have to play their best to get as far as possible. Fight on a mysterious planet with randomly spawning enemies and bosses, either alone or with 3 friends in online co-op. If you enjoyed this game, see our list of games similar to Risk of Rain.

    View Game
  44. 94%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:stability, grinding
    94% User Score Based on 160 reviews

    Attention! The Overlord has enacted some new laws to keep the galaxies safe and peaceful. He's not a bad guy - he just doesn't want things to get out of hand. And some stupid rebels are already stirring things up, which isn't cool. Order has been restored, and revolutions are definitely not allowed. There are loads of weapons, items, skills and even potions out there for sure. But they're strictl… If you enjoyed this game, see our list of games similar to DIG - Deep In Galaxies.

    View Game
  45. View Game
  46. View Game
    87%Game Brain Score
    Most mentioned positive aspects:music, story
    Most mentioned negative aspects:stability, optimization
    87% User Score Based on 1,206 reviews

    Your music is under attack… You must liberate it! In Symphony, you fight through levels uniquely generated by your own song collection, discover items and vanquish bosses to defeat the evil within! With Symphony, we wanted to push the limits of user-music-based gameplay and focused on two concepts: Your music creates the game Every song has a unique emotion, sound and rhythm, and we wa… If you enjoyed this game, see our list of games similar to Symphony.

    View Game
  47. View Game
    69%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    68% User Score Based on 235 reviews
    Critic Score 73%Based on 2 reviews

    The quiet hamlets of the Vale stand defenseless... No walls, no moats, not even a presentable fence. You'll have to use your resources wisely to transform each village from farm-town to fortress. Build defenses, train troops, and hold the line with powerful heroes in ValeGuard, a Defensive Strategy game. If you enjoyed this game, see our list of games similar to ValeGuard.

    View Game
  48. 91%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, optimization
    91% User Score Based on 436 reviews

    A mini action rogue-lite with chaotic spell-slinging hack-n-slash combat. Collect spells and perks to become an unstoppable wizard and destroy hordes of monsters. If you enjoyed this game, see our list of games similar to Neophyte.

    View Game
  49. 69%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:optimization, stability
    69% User Score Based on 110 reviews

    Atomine is a twin stick procedural shooter rogue-lite set in a virtual world with minimalist design, where the player recounts on the screen the real events of Stuxnet, the first weapon ever created in the form of computer virus. In every run the player has to clear the level area from all the enemies in order to unlock the portal to the next level. During the run every killed enemy will leave on … If you enjoyed this game, see our list of games similar to ATOMINE.

    View Game
  50. 81%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, stability
    81% User Score Based on 211 reviews

    A single star fighter trying to save as many civilians as possible before they are overrun by a marauder armada. You'll need to gather new weapons, upgrade your ship, find resources, trade with other ships and more to overcome the challenge before you. If you enjoyed this game, see our list of games similar to Power of Ten.

    View Game