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Games like MUTARIUM: Mutant Aquarium Defense

Games like MUTARIUM: Mutant Aquarium Defense

Games like MUTARIUM: Mutant Aquarium Defense

Looking for games like MUTARIUM: Mutant Aquarium Defense? Here are top casual management recommendations with a science fiction focus, selected from player-similarity data — start with Heart of Bone, Bug Alliance or Star Purr.

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  1. 51%Game Brain Score
    51% User Score Based on 2 reviews

    You wake up again—your bones soaked in blood. Demo Available NOW! Play the free demo and get a SMALL BLOODY SLICE of the gameplay! Full Release – December 15 The FULL roguelike experience, with constant and explosive progression: including TONS of enemy types, abilities, weapons, and rooms. Prepare to dive into the full story—an intertwined experie… If you enjoyed this game, see our list of games similar to Heart of Bone.

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  2. 52%Game Brain Score
    52% User Score Based on 3 reviews

    Bug Alliance is a top-down Action Roguelite where every run is a new experiment—and every level-up is a real decision. Fight through escalating waves, shape your build through upgrades and Synergies, and earn your progress across a story-driven campaign that rewards mastery. Earth didn’t just fall—it turned desperate. As forests vanished and survival collapsed, humans engineered bugs to last longe… If you enjoyed this game, see our list of games similar to Bug Alliance.

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  3. A little catnip. A galaxy's worth of trouble. One melancholic cat. One bad batch of catnip. Behind its eyes, mouse fleets are massing, rainbow portals are tearing open, and a whole universe is waking up. There's only one way out of this trip: survive it. Star Purr is a single-player roguelite space shooter about auto-firing weapons, razor-sharp dodging, and an arsenal you rebuild from scratc… If you enjoyed this game, see our list of games similar to Star Purr.

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  4. View Game
    87%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:replayability, grinding
    87% User Score Based on 164 reviews

    Duncrush is a clicker RPG where you attack monsters by clicking and conquer challenging dungeons!Click on monsters to defeat waves of enemies, collect gold, and find powerful weapons, shields, and accessories.Strengthen your character through a deep skill tree and customize your build with unique equipment. Explore a variety of dungeons, each with different challenges and rewards.With simple contr… If you enjoyed this game, see our list of games similar to Duncrush.

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  5. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:stability, grinding
    85% User Score Based on 9,352 reviews

    Dungeon of the Endless is a roguelike-like tower defense game. The player takes the role of survivors in a prison spaceship after its escape pods crash landed on a planet on their way to the Auriga system, which they were supposed to colonize as slaves. If you enjoyed this game, see our list of games similar to Dungeon of the Endless.

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  7. A jumping spider is not a houseplantFeed them. Mist them. Notice when one stops eating, because that is what a spider does in the days before a moult -- and a moult is when it is most fragile. Bring it through, and it comes out a size larger, one instar further along, sometimes down a leg it will spend the next few moults regrowing. Your first spiders are Phidippus imaginarius -- a fictional ju… If you enjoyed this game, see our list of games similar to Salticidae Story.

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  8. Hold It In is a hardcore sci-fi tower defense roguelite, focussed on deep strategic combat and sandbox play. You play as a commander who must use at everything at your disposal to hold closed a rift, from which interdimensional horrors are staring out, ready to end our world if the shields are breached.  The game all takes place in a 360 degree battlefield, with the rift at the center, and a… If you enjoyed this game, see our list of games similar to Hold It In.

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  9. ABOUT THIS GAMEBullet Meltdown is best described as Brotato meets Tower Defense, a bullet heaven arena shooter with base building, AI companions, and permanent progression. Get overpowered every run. BECOME OVERPOWEREDEvery run is a hunt for power. Tear through waves of enemies, grab coins mid-chaos, and spend them in the shop on weapons and upgrades that stack into insane combinations. Pick up… If you enjoyed this game, see our list of games similar to Bullet Meltdown.

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  10. Thousands of slimes march on your base, and each one is simulated individually, with its own weight and collisions. There's no path painted on the ground: the horde looks for the shortest route and squeezes through wherever it narrows. When it hits a wall, it piles up, slimes climb on top of each other, and if the wall is low, the mass pours right over it. And they're not all the same. The small… If you enjoyed this game, see our list of games similar to Slime Break.

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    The map is never the same twice.Every VOLTWOOD map is procedurally generated. The checkpoints, the resources, the blockers, the enemy types and amounts are a unique combination every time you play. If you want to replay or share a map, use its map ID.You compete to maximize kills, not just kill the wave.VOLTWOOD is a maze-building tower defense built to be competitive. Kill as many enemies as you … If you enjoyed this game, see our list of games similar to Voltwood.

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  12. 77%Game Brain Score
    Most mentioned positive aspects:gameplay, emotional
    Most mentioned negative aspects:graphics, replayability
    77% User Score Based on 132 reviews

    Game Description: Become the hero of a fantasy world and stop the monster invasion! Legacy of Defense combines innovative side-scrolling action with deck-building elements. Embark on an adventure, recruit allies, and defend yourself from dangerous foes! Key Features: Side-Scrolling Action: Experience intense battles with stunning 2D graphics and intuitive controls. Feel the thrill of defen… If you enjoyed this game, see our list of games similar to Legacy of Defense.

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  13. 84%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, optimization
    84% User Score Based on 2,330 reviews

    Prepare to die, humans!A group of people wake up in a strange post-apocalyptic labyrinth — naked, with no memories and with a bunch of weapons. Is this a joke, a crazy experiment, or... a game? You'll find out soon enough, just try not to die first! Get your pretzels readyYour puny squad is capable of much more. Choose your loot and transform the squishy humans into wizards, cultists, ninjas … If you enjoyed this game, see our list of games similar to Despot's Game: Dystopian Battle Simulator.

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  14. 72%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:graphics, story
    72% User Score Based on 83 reviews

    Words Can Kill is a fusion of roguelike deckbuilders and word games. Travel through the world trying to find the perfect combination of letters, weapons and armor. And remember, here your decisions matter, not your vocabulary! If you enjoyed this game, see our list of games similar to Words Can Kill.

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  15. 49%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:music, stability
    49% User Score Based on 277 reviews

    Steam Marines is a squad based Roguelike set on a steampunk spaceship. It features tactical play focused on positioning and careful use of resources. Built to keep you on your toes as you progress through the decks of your besieged ship while clearing enemies and trying to reach each level's elevator. If you enjoyed this game, see our list of games similar to Steam Marines.

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  17. 88%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:story, grinding
    88% User Score Based on 132 reviews

    These Doomed Isles: The First God is a prologue chapter of the main game, These Doomed Isles. Play as Cernunnos, the Celtic god of nature, and lead the Celtic civilisation to victory against waves of invaders, curses and more! Raise land from the sea, build a settlement for your followers and provide them with the means to gather the resources they need to prosper. Expand from humble beginnings t… If you enjoyed this game, see our list of games similar to These Doomed Isles: The First God.

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  18. The board is a toy box. The horde is climbing. Every throw counts.PachiRogue blends pachinko physics with roguelike drafting and horde-survival pressure—without having to kite or dodge. You stand at the top of a handcrafted papercraft diorama, load balls from your hopper, and fire into climbing waves of enemies. Enemies stay still while your shots bounce and cascade; once your throws are spent, t… If you enjoyed this game, see our list of games similar to PachiRogue.

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    Welcome to OreiaThe cave is rich, unstable, and on the clock. Drop in with a pick and a contract, build a mining operation worth defending, and be gone before the cave collapses - everything you can't ship out stays buried. Swing the pick, read the wallEvery tile can pay out or blow up. Iron, silver and gold sit next to gas pockets that vent creeping clouds, buried traps on a half-second fuse, … If you enjoyed this game, see our list of games similar to Oreia.

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  20. [h1]NINJA SURVIVOR[/h1] [b]Survive the impossible. Forge your legend.[/b] A fast-paced roguelike survival action game where you fight endless waves of enemies with an ever-growing arsenal of mystical ninja weapons. Master the way of the blade across 5 brutal stages, each filled with demons, dragons, and shadow beasts. [h2]⚔ FEATURES ⚔[/h2] [list] [*][b]6 Unique Weapons[/b] — Shuriken, Kunai, … If you enjoyed this game, see our list of games similar to Ninja Survivor.

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  21. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:graphics, music
    90% User Score Based on 83 reviews

    Cursed Forest A vast forest teeming with life, Noctful, has flourished for ages under the protection of mushroom magic-wielding elves. However, a deeply resentful oak has cursed and corrupted the forest. As a guardian elf, rally animal allies and use mushroom skills to defend your base and purify the forest! Defend Your Base and Defeat the Boss To purify the cursed forest and summon allies, you’ll… If you enjoyed this game, see our list of games similar to Forest Heroes.

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  22. View Game
    85%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:replayability, story
    85% User Score Based on 484 reviews

    Sipho is an action survival game with an intricate building system. Grow your own creature and take over the local ecosystem. Fight, grow, survive, dominate. If you enjoyed this game, see our list of games similar to Sipho.

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  23. View Game
    69%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:replayability, optimization
    69% User Score Based on 97 reviews

    Congratulations, Operator #8 You have been randomly selected for the ITER Corporation’s exciting vertical ventures department. Drill the pillars that encircle our homeworld, extract essential resources, and try not to get obliterated in the process. If you fail, don’t worry, your replacement will be along shortly - probably with a better attitude. > Mining 101 Crack open the Pillars like a big hap… If you enjoyed this game, see our list of games similar to ITER-8.

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  24. 91%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:graphics, music
    91% User Score Based on 365 reviews

    Bioprototype, a Roguelike & Skill Customizing Rhapsody! This is an auto-bomber with programming elements. Customize your character skills with visual programming, utilize enemy organs to finish the mutation, and construct the ultimate prototype, one can survive in the endless wave of flesh. • Set your own skill trigger logics • More builds: Bullet Master, Flesh Army, Virus Master, and more • 24 u… If you enjoyed this game, see our list of games similar to Bioprototype.

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  25. 67%Game Brain Score
    Most mentioned positive aspects:music, graphics
    Most mentioned negative aspects:gameplay, grinding
    86% User Score Based on 29 reviews

    Fishing Mega-Game is a fishing creature collector that's all about fighting fish to catch fish! You play as an angler who uses the fish they catch as bait for the next big one. Collect dozens of vibrant fish and unlock unique ability combinations to challenge the hordes of fish wishing to take the bait themselves. Fishing and SurvivingWhile fishing, send your bait into a fishing hole full of hu… If you enjoyed this game, see our list of games similar to Fishing Mega-Game.

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  26. View Game
    83%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    83% User Score Based on 266 reviews

    You! the most outstanding pioneer who graduated from this kingdom, are finally about to embark on your legendary journey. Construct towns across various levels to fend off waves of attacks from diverse enemies until you establish a firm footing and complete your exploration! Build your own mini town Expand progressively on the barren map, construct a complete town, and uncover rarer buildings an… If you enjoyed this game, see our list of games similar to Border Pioneer.

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  27. 87%Game Brain Score
    Most mentioned positive aspects:story, graphics
    Most mentioned negative aspects:gameplay, monetization
    93% User Score Based on 110 reviews
    Critic Score 81%Based on 11 reviews

    The Last Friend is a tower-defense game beefed up with strategic Beat 'em-up elements, where players must balance their attack and defense tactics to defend their mobile dog shelter. If you enjoyed this game, see our list of games similar to The Last Friend.

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  28. Mine. Haul. Survive.You keep a lonely research station anchored above the ocean floor. Swim down, vacuum your way through sand and rock with your suction hose and fill your cargo with ore. When the clock runs out, the creatures of the deep come for your station, and you had better be back at the cannon. Dig your own way downThe seabed is destructible pixel by pixel. Deeper layers hold rarer ore… If you enjoyed this game, see our list of games similar to Coral Outpost.

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  29. One siege. Twenty minutes. Zero mercy. MAZEHOLD is a tower defense roguelite without waves. The horde keeps pouring in while you build, adapt and fight – and when the clock hits zero, the Demon Lord marches on your castle himself. If he gets through, the run is over. Instantly. No matter how many lives you have left. Every tower is a wall. Every wall is a weapon. You don't just defend the p… If you enjoyed this game, see our list of games similar to Mazehold.

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  30. An RPG that keeps you company while you work The Seven Beacons lives in a 110-pixel strip resting on top of your Windows taskbar. Your party fights there, in plain sight and out of your way, while you write, study or code. It doesn't ask you to watch: it moves on its own, and when you have a minute you open the panel and make the calls. The Realm of Asteria broke when the Demon King snuffed out t… If you enjoyed this game, see our list of games similar to The Seven Beacons.

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  31. GRIDNOVA is a top-down bullet heaven roguelike set on a neon digital grid. The player controls the Core, which fires automatically while the player moves through growing swarms of enemies, mini-bosses and bosses. Each level-up offers a choice of weapons and upgrades; pairs of weapons unlock synergies, and fully upgraded weapons can evolve into stronger forms. A standard run lasts twenty minutes, … If you enjoyed this game, see our list of games similar to GRIDNOVA.

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  32. A Neon-Soaked Fusion of Action and Strategy Welcome to Command-Ω 2, the ultimate synthwave tower defense shooter. Plunge into a retro-futuristic battlefield where quick reflexes and sharp tactical decisions are your only lifelines. Take direct control of your base's firepower while deploying and awakening automated towers to hold back the relentless cyber-horde. Adapt and Overcome with Roguelite … If you enjoyed this game, see our list of games similar to Command-Ω Omega 2.

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  33. The jungle's Membrane has torn open, and the hordes pouring out of it don't stop coming. You begin as a loinclothed servant with nothing but flimsy bow and a rusty sword and by the end of a run, you're an unstoppable Amazon king holding the encircling trenches against everything the jungle can throw at you.  Every run is a new experience. Adapt to whatever boons, weapons, and companions the run… If you enjoyed this game, see our list of games similar to The Membrane.

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  34. Defend your base in this Roguelite survival shooter TD! Mix random skills + evolve gems to craft your Build. 5-min fast rounds, intense zombie & ghost hordes. Triple progression: Spirits, guns, heroes. Easy to learn, hard to put down. Low barrier, high ceiling. Every run is fresh! If you enjoyed this game, see our list of games similar to Ghosts Keep Out.

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  35. A sci-fi space station defense auto-shooter where you repel enemy fleets with missiles, mass drivers, phase weapons, and railguns. Upgrade your arsenal, adapt your build, and hold the line against overwhelming odds. If you enjoyed this game, see our list of games similar to STELLAR BASTION.

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  36. 87%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, replayability
    87% User Score Based on 760 reviews

    A short relaxing incremental game disguised as a tower defense, but enemies can’t reach your walls. Thanks to lava. If you enjoyed this game, see our list of games similar to Zero Stress King: Idle Defense.

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  37. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    95% User Score Based on 87 reviews

    Hyperspace Dogfights is a juicy jet-combat roguelike in which you blast, dodge and slice your way through masses of technologically inferior enemies. During the mission your craft will evolve into something stronger and weirder by gathering some of the 200+ items available ingame. If you enjoyed this game, see our list of games similar to Hyperspace Dogfights.

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  38. 68%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:grinding, graphics
    68% User Score Based on 123 reviews

    Defend. Upgrade. Dominate. A relaxing incremental base-defense game, packed with powerful skills and a deep skill tree. If you enjoyed this game, see our list of games similar to Incrempire.

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  39. View Game
    87%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, replayability
    87% User Score Based on 370 reviews

    Legionbound is a retro party-based RPG where fights play out in modern autobattler style, where the choices you make when selecting your heroes makes the difference between huge runs and getting wiped. Recruit a ridiculous number of heroes, stack synergies, and see if your legion holds together when the enemies pour in wave after wave. Build up your party to up to 50 heroes at the same time. A far… If you enjoyed this game, see our list of games similar to Legionbound.

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  40. View Game
    90%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, replayability
    90% User Score Based on 1,088 reviews

    Tangy TD: Hero Tower Defense, Class Based, Roguelite, Item CombiningStrategic tower defense where you play a witch, place class-based towers, equip them with items that grant powerful abilities, combine them, create unique builds & deal ridiculous amounts of damage! Customize your builds with a deep stat system and giant skill tree! Move around Towers, Fight Big Bosses! Spend Skillpoints earn… If you enjoyed this game, see our list of games similar to Tangy TD.

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  41. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:graphics, story
    90% User Score Based on 293 reviews

    Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun! Have fun surviving Spartan! Spartan Survivors includes 10 playable levels 5 difficulty modes 21 weapons for a total of 105 evolutions // 14 perks with 56 upgrades 8 playable characters with their unique weapons, perks & stats Unlock Custom Game to tailor the game th… If you enjoyed this game, see our list of games similar to Spartan Survivors.

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  42. View Game
    59%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    100% User Score Based on 10 reviews

    STORY:​​ 2060: An ancient nano-disaster erupts in Antarctica! Leaked doomsday weapons mutate creatures into killing machines, pushing human defenses to the brink. YOU—one of the finest frontline commanders—are urgently tasked with leading the experimental Gen-3 ​​Humanoid Mech Units​​ in a last stand, buying time for civilian evacuation to near-Earth orbit! ​​GAMEPLAY:​​ ​​CUSTOM UNIT DEPLOYMENT​… If you enjoyed this game, see our list of games similar to Maid Mech.

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  43. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding
    95% User Score Based on 1,455 reviews

    Astro Prospector is an incremental bullet heaven about mining cofferoids and fighting SpaceCorp. Collect resources, upgrade your ship and become unstoppable. Return AstroCoffee to humanity! If you enjoyed this game, see our list of games similar to Astro Prospector.

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  44. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    85% User Score Based on 520 reviews

    Welcome to Ocean Keeper, a mining roguelike shooter with a top-down view. Play as a Miner whose spaceship has crashed on a planet, filled with underwater monsters. Find resources and artifacts for purchasing valuable upgrades. Use the time between each attack to power up your diver, mech, weapon or explore a new dungeon. Build automatic turrets, use drones to collect loot and improve your skill… If you enjoyed this game, see our list of games similar to Ocean Keeper: Dome Survival.

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  45. 96%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:replayability, stability
    96% User Score Based on 108 reviews

    Space Raiders in Space is a wave defense roguelike mixing squad management and tower defence mechanics. Command your almost competent crew to loot weapons and supplies, build defenses, and fight their way through the Bugpocalypse. If you enjoyed this game, see our list of games similar to Space Raiders in Space.

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  46. 79%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    81% User Score Based on 169 reviews
    Critic Score 73%Based on 3 reviews

    A dieselpunk real-time tactics roguelite set in an alt-history World War 2. Grit and Valor – 1949 puts you in command of an elite Mech Squadron. Think fast and battle the Evil Axis forces to liberate Europe. Upgrade your Mechs and Pilots and develop new strategies to neutralise the enemy HQ! If you enjoyed this game, see our list of games similar to Grit and Valor - 1949.

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  47. View Game
    86%Game Brain Score
    Most mentioned positive aspects:graphics, replayability
    Most mentioned negative aspects:gameplay, story
    86% User Score Based on 130 reviews

    “Crawling Lab,” a secret laboratory built by Selen Industry deep in the mountains. Here, a new product using the newly developed artificial life form "Biodoll" was being researched. But one day, a web-crawling AI hijacks a new Biodoll and An incident occurs in which she calls herself the "Crawl Queen" and takes control of all the facilities in the laboratory. The protag… If you enjoyed this game, see our list of games similar to Crawling Lab.

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  48. 83%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:grinding, stability
    88% User Score Based on 4,481 reviews
    Critic Score 78%Based on 27 reviews

    Have a Nice Death is a 2D action roguelite where you play as an overworked Death, whose employees have run rampant, completely throwing off the balance of souls - and his vacation plans. In order to restore order, you'll have to grab your trusty scythe and show your employees who's boss. If you enjoyed this game, see our list of games similar to Have a Nice Death.

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  49. 71%Game Brain Score
    Most mentioned positive aspects:gameplay, humor
    Most mentioned negative aspects:story, grinding
    71% User Score Based on 340 reviews

    You’re being Bounty-Hunted! Run, Build your ship piece-by-piece and make it work with the parts you find, Destroy outposts and waves of fleets, and Pick your battles carefully to overcome your hunters in this Fast-Paced Top-Down Action Roguelite Shooter. If you enjoyed this game, see our list of games similar to Run Build Pew!.

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  50. View Game
    87%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, stability
    87% User Score Based on 1,142 reviews

    Buggos is an RTS Auto Battler where you direct a bug swarm to conquer the planet from the dirty resident humans! You unlock evolution points when defeating the humans in battle allowing you to customize your bug swarm. You are the bad guys! You are the evil bugs! You are here for blood! If you enjoyed this game, see our list of games similar to Buggos.

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