Games like Bio Inc. Total Defense

75%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, music

75% User Score Based on 478 reviews

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy. If you enjoyed this game, see our list of games similar to Defend Your Life: TD.

61%Game Brain Score

Most mentioned positive aspects:music, story

100% User Score Based on 12 reviews

Listeria Wars is a tactical strategy where we protect the hero’s body from various infections and viruses by controlling the troops of the immune system. We can observe his personal life and even influence it with side effects. If you enjoyed this game, see our list of games similar to Listeria Wars.

86%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, replayability

86% User Score Based on 2,612 reviews

Sir, We Have an Orc Problem is a short tower defense game with incremental-style meta-progression. A bazillion orcs Defend your base against an overwhelming number of orcs. They're coming with tens of thousands of troops to overrun you. Greet them with even more bullets, bombs and lasers! Massive upgrade tree Use resources earned from every run, won or lost, to unlock and upgrade powerful turrets.… If you enjoyed this game, see our list of games similar to Sir, We Have an Orc Problem.

90%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, stability

91% User Score Based on 9,743 reviews

Critic Score 88%Based on 1 reviews

The Riftbreaker Gold Edition contains the core game and all available addons If you enjoyed this game, see our list of games similar to The Riftbreaker.

95%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:music, stability

95% User Score Based on 1,207 reviews

WHAT IS INCLUDED IN THE PROLOGUE?The Riftbreaker Prologue allows you to experience the events taking place before the story campaign of the main game. Explore an entirely new world. Gather resources. Build up a base. Defend yourself from thousands of alien creatures. Or just take the scenic route and do whatever you want - the choice is yours.STORYYou play the role of captain Ashley S. Nowak - you… If you enjoyed this game, see our list of games similar to The Riftbreaker: Prologue.

87%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

90% User Score Based on 1,732 reviews

Critic Score 70%Based on 1 reviews

Take command of your mercenary forces in Atom Zombie Smasher. The zombie apocalypse is upon us and it's up to you to evacuate everyone before they fall prey to the undead. If you enjoyed this game, see our list of games similar to Atom Zombie Smasher.

77%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:optimization, stability

77% User Score Based on 2,424 reviews

Find patient zero before an alien virus takes over San Francisco and the cepheus protocol is enacted. Command your squad, save civilians, and stop the Pangu virus. Kill patient zero and save the world. If you enjoyed this game, see our list of games similar to Cepheus Protocol.

77%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

84% User Score Based on 5,530 reviews

Critic Score 66%Based on 5 reviews

In the RTS-game “Diplomacy is Not an Option” you will become a medieval feudal lord in a midlife crisis. Due to your position you must constantly make hundreds of decisions a day related with city management and economic development. You are tired of this monotonous and, so it seems, meaningless existence. But things are about to change: hordes of bloodlusted enemies, swarms of scary monsters and … If you enjoyed this game, see our list of games similar to Diplomacy is Not an Option.

74%Game Brain Score

Most mentioned positive aspects:story, graphics

Most mentioned negative aspects:stability, monetization

80% User Score Based on 510 reviews

Critic Score 65%Based on 7 reviews

From the team that brought you 8-Bit Armies comes a new fantasy RTS as fast-paced and friendly as the original! 8-BIT HORDES is a colorful strategy-arcade game that is easy to learn for players of all skill levels. Collect resources, build up and defend your base, amass your army of orcs or humans and ultimately crush your opponents! 8-Bit Hordes features offline single-player missions, two-player… If you enjoyed this game, see our list of games similar to 8-Bit Hordes.

Cell Defense is an incremental tower defense set inside the body. You command a single antibody at the center of the cell while viruses, bacteria, and mutating swarms pour in from every side. Survive, bank what you earn, and pour it into weapons, cards, and upgrades that shape your build and push the next run further than the last. Survive, earn, repeatPlan a build, start a run, and collect the… If you enjoyed this game, see our list of games similar to Cell Defense.

41%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, optimization

67% User Score Based on 12 reviews

Welcome to the Dark Ages, now in color! Medievaly is a real-time strategy game for everyone feeling a little bit Medievaly - or just wanting their own colorful kingdom to enjoy (while fending off relentless attacks from encroaching enemies).  Come for the Middle Ages, stay for dynamic battle simulations where everything can happen, RTS mechanics, and a whole lot of tactical gameplay! Re… If you enjoyed this game, see our list of games similar to Medievaly: Battle Simulator.

95%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:grinding, music

95% User Score Based on 577 reviews

The wait is over! The full version of "There Are No Orcs" is OUT NOW! Join the Horde... (of Players)! Find the Discord invite link in the game's main menu or in the sidebar of this Steam page. We're Not Done Yet! We'll keep rolling out new content, squashing bugs, and generally trying to make this game even more awesome for you. Thanks for the incredible support! "There A… If you enjoyed this game, see our list of games similar to There Are No Orcs.

64%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

71% User Score Based on 1,268 reviews

Critic Score 57%Based on 13 reviews

"From the Star Wars: Empire at War and Command & Conquer veterans at Petroglyph comes the first-ever strategy game set in the barbaric world of Conan the Barbarian. Conan Unconquered is a strategy game set in the barbaric world of Conan the Barbarian where you must build your stronghold and assemble an unconquerable army to survive the savage hordes of Hyboria. Wave after wave of increasingly mor… If you enjoyed this game, see our list of games similar to Conan Unconquered.

85%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:stability, grinding

85% User Score Based on 955 reviews

Unleash voxel warfare in 9-Bit Armies: A Bit Too Far. Lead a modern military, build bases, unlock units, and attack in all-out war. Engage on land, sea and air in over 30 missions, online skirmishes, or co-op. Easy to learn, a challenge to master. If you enjoyed this game, see our list of games similar to 9-Bit Armies: A Bit Too Far.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, replayability

91% User Score Based on 211 reviews

Experience the brutality and randomness of war as an Allied tactical commander in the Pacific Theater during World War 2. Train, equip, and command a squad of soldiers as you fight against the fanatical Imperial Japanese Empire. If you enjoyed this game, see our list of games similar to Skirmish Line.

70%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:graphics, stability

66% User Score Based on 833 reviews

Critic Score 80%Based on 3 reviews

Kingdom Wars II: Battles brings a fresh perspective on the fantasy real-time Strategy genre, combining the best of Zombie survival and long term crafting with complex fast-paced city-building and skirmish siege combat. All in a beautifully, yet gory game world where players fight across the epic battlefields in multiplayer skirmish and coop with thousands of other players. And with an episodic sin… If you enjoyed this game, see our list of games similar to Kingdom Wars 2: Battles.

93%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:stability, grinding

93% User Score Based on 1,384 reviews

Relive Your Childhood Toys comes to life! Build your Army Toys, make battle scenario, watch the Toys battling each other, and customize your play with Attack on Toys Toy Box. Command your Army Toys to fight against another toys strategically and keep them alive during battle! Attack on Toys is a 3rd-person shooter mixed with combination of Real-time strategy as Toy Army Soldiers. Pick your favour… If you enjoyed this game, see our list of games similar to Attack on Toys.

74%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, stability

77% User Score Based on 900 reviews

Critic Score 66%Based on 3 reviews

Who needs backstory? Who needs resource-gathering? Diplomacy is so last year. Gratuitous Space Battles cuts right to the chase of sci-fi strategy games, and deals with large, completely unjustified space battles between huge opposing space fleets. If you enjoyed this game, see our list of games similar to Gratuitous Space Battles.

95%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

95% User Score Based on 3,795 reviews

The fourth installment of the real-time strategy series again tasks the player with containing the creeper, a destructive fluidlike substance, slowly overtaking the map's surface. Creeper World 4 continues the series' gameplay and favors 3D environments with a focus on fluid dynamics over traditional 2D graphics. If you enjoyed this game, see our list of games similar to Creeper World 4.

65%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

66% User Score Based on 110 reviews

Critic Score 60%Based on 1 reviews

In a near future, the world has been devastated by a virus turning humanity into zombies. You are Iron Corps, the last defense of civilization traveling the world to find resources, help people and find answers. Will you survive long enough? If you enjoyed this game, see our list of games similar to Zombie City Defense 2.

95%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

95% User Score Based on 3,588 reviews

Command a team of 5 elite soldiers against an alien horde of 100,000. Surrounded on all sides, you must outmaneuver and outsmart the enemy. If you enjoyed this game, see our list of games similar to Infested Planet.

93%Game Brain Score

Most mentioned positive aspects:graphics, replayability

Most mentioned negative aspects:gameplay, story

93% User Score Based on 337 reviews

★ Attack on Toys: LOCAL & ONLINE SPLIT-SCREEN - 2025 UPDATE! NOW AVAILABLE!★ Remembering playing Split Screen with family or goes to friend house and bringing your own controller & memory card? You could do exactly that with Attack on Toys! Fully Dynamic Offline / Online Split Screen and Multi Profile - Save Data Memory System! Please see below for more details & features about the S… If you enjoyed this game, see our list of games similar to Attack on Toys.

79%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

90% User Score Based on 1,786 reviews

Critic Score 50%Based on 3 reviews

AI War II is a grand strategy/RTS hybrid against an overwhelming, inhuman enemy who has conquered the galaxy. The enemy has made only a single error: underestimating you. You must steal as much technology as you can, and take enough territory to fortify your bases and launch your attacks. If you enjoyed this game, see our list of games similar to AI War 2.

87%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

93% User Score Based on 6,499 reviews

Critic Score 67%Based on 2 reviews

A beautifully hand-crafted real-time micro strategy with Vikings. If you enjoyed this game, see our list of games similar to Bad North.

Idle Defense throws you into a hypnotic, minimalist arena where neon cubes of every color surge toward you. You can crush them yourself or build an automatic defense grid that grinds them down while you strategize. This isn't just another idle game. It's a deep, neon-soaked loop of progression, prestige, and pure destruction. KEY FEATURES: Dual-Mode Destruction – Play actively by smashing … If you enjoyed this game, see our list of games similar to Idle Defense.

https://store.steampowered.com/widget/2244400/ Ready yourself to Pop that Button!Craft a powerful defense and drive back the waves of evil buttons! With an array of turrets, utilities and traps, fight your way through a variety of lush environments - Earn coins and parts with every victory and design your very own button! Be the Button you've always wanted!Earn coins and expand your collection o… If you enjoyed this game, see our list of games similar to Button Pop.

68%Game Brain Score

Most mentioned positive aspects:story, music

Most mentioned negative aspects:gameplay, grinding

81% User Score Based on 36 reviews

IDUN: Prologue is a single-player action RTS with a story campaign. The prologue lets you try a portion of the main game with only a limited number of turrets, tools, and heroes. Step into the arena with IDUN: Prologue, a thrilling slice of our full-length defense RTS where real-time strategy meets rogue-lite chaos. Get a sneak peek at the intense arena mode, where you’ll face overwhelming enemy … If you enjoyed this game, see our list of games similar to IDUN Prologue - Frontline Survival.

44%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:monetization, stability

73% User Score Based on 11 reviews

In the dark ages, when ancient kingdoms fell under the onslaught of ruthless enemies, the last surviving castle became a symbol of hope for humanity. This castle is not just a fortress made of stone, but a magical stronghold capable of summoning brave soldiers to the battlefield, ready to fight until their last breath. You are the guardian of this stronghold, chosen by fate to lead the resistance … If you enjoyed this game, see our list of games similar to Winning Tactics.

Command your virus to invade cells, wage an all-out war against the immune system, and conquer the world. Cell Battlefield Cells are the primary battlegrounds of the game. You need to command your virus to enter host cells and utilize the replication mechanisms within the cell nucleus to rapidly reproduce. As the virus multiplies, the host cell's apoptosis signaling pathway will gradually be act… If you enjoyed this game, see our list of games similar to Propa..

Create Chaos: Pattern Survivors – Unleash creativity in a unique bullet hell roguelite Pattern Survivors: Bullet Hell (Roguelike) is a dynamic action game where you take control of your cosmic tower and design attack patterns yourself to stop hordes of enemies! This is not another Vampire Survivors clone – this is a bullet hell where YOU create the chaos. The Patterns appeared sudd… If you enjoyed this game, see our list of games similar to Pattern Survivors: Bullet Hell (Create Chaos).

49%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, music

48% User Score Based on 336 reviews

Critic Score 50%Based on 2 reviews

Oil Rush is a naval strategy game that takes place in a world where nuclear war has melted the ice caps, changing the face of the planet forever. Oil Rush offers unique gameplay, avoiding micromanagement of every single unit, while still providing full control over all important aspects of strategy and economy. If you enjoyed this game, see our list of games similar to Oil Rush.

62%Game Brain Score

Most mentioned positive aspects:humor

Most mentioned negative aspects:gameplay, graphics

100% User Score Based on 13 reviews

Make yourself comfortable, put on your headphones, and get ready to conquer cyberspace! HexaScape: Cyber Defense is an addictive mix of hex grid puzzler and tower defense mechanics, creating a compelling turn-based strategy game. - Board game-like mechanics - If you know the board game classic Carcassonne, you’ll instantly feel at home in HexaScape. Players determine the course of the game by pla… If you enjoyed this game, see our list of games similar to HexaScape: Cyber Defense.

80%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, monetization

80% User Score Based on 293 reviews

Explosive singleplayer action RTS with a story campaign. Hold the line against massive swarms on a fully simulated battlefield. If you enjoyed this game, see our list of games similar to IDUN.

55%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

87% User Score Based on 15 reviews

Gelluloid Domination is a fast-paced strategy game of fantasy biology. Start with a single fragile cell and expand across the network, assimilating rivals to grow your gel-powered army. Evolve mutations, unlock new abilities, and outmaneuver deadly pathogens. Adapt and conquer, expand or be consumed. Every decision shapes the network — will you achieve total domination? If you enjoyed this game, see our list of games similar to Gelluloid Domination.

87%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:monetization, grinding

87% User Score Based on 9,997 reviews

Lead legions of soldiers to defend your empire! If you enjoyed this game, see our list of games similar to Grow Empire: Rome.

84%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, replayability

84% User Score Based on 120 reviews

Commander, your strike team is to dive deep into the contaminated city of Sun Stone and get some answers before the mysterious deadly plague spreads . Good luck Commander! If you enjoyed this game, see our list of games similar to Welcome Back, Commander.

88%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:music, optimization

88% User Score Based on 172 reviews

Build epic bases, lead troops, and defend against enemy hordes! If you enjoyed this game, see our list of games similar to Block Fortress 2.

77%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

93% User Score Based on 2,799 reviews

The Cataclismo left us broken. Construct fortresses and defend against waves of Horrors in this mix of tower defense and real-time strategy. Lead an expedition beyond the gates of the last city, and reclaim mist-shrouded ruins as you rebuild humanity—stone by stone. If you enjoyed this game, see our list of games similar to Cataclismo.

92%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

92% User Score Based on 51 reviews

Repterra is a base-building survival RTS set in a world overrun by dinosaurs. Manage your colony while battling massive dino hordes. Breed and ride your own dinos, unlock permanent upgrades, and fight to reclaim the world for humanity. Massive ColoniesBuilding a massive colony is essential. Construct sprawling defences, set up vast production lines, and establish powerful grids to fuel your outpos… If you enjoyed this game, see our list of games similar to Repterra.

97%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

97% User Score Based on 1,378 reviews

From Glory To Goo is a Sci-Fi Survival RTS set on an alien world. Serve as humanity's bulwark by establishing a colony and supporting your colonists still in orbit. But beware, for The Goo, a relentless and shape-shifting force approaches from all sides, even above and below. Expand Your ColonyExpand your colony in a hostile alien environment and ensure you can supply enough shelter, water and pow… If you enjoyed this game, see our list of games similar to From Glory To Goo.

80%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:stability, story

80% User Score Based on 213 reviews

Versus is a fast action twin-stick shooter from the creator of Nation Red. Create your own sandbox defense before doing battle with thousands of enemies in fast-paced top down combat. Face up to a dozen bosses. Simultaneously. Play in single player, on-line or local coop with up to 4 players. If you enjoyed this game, see our list of games similar to VERSUS SQUAD.

57%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, stability

56% User Score Based on 108 reviews

Critic Score 60%Based on 1 reviews

A Medieval Real-Time Strategy game combining classic RTS elements with modern fast-paced, epic scale single and multiplayer battles across beautifully rendered 3D maps. If you enjoyed this game, see our list of games similar to Avalon Lords: Dawn Rises.

53%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, story

76% User Score Based on 21 reviews

Ifectra is a strategy game set in 2124 on the distant planet Emevera III, ruled by the Maxploit Corporation, where an epidemic of a yet unknown virus broke out. The corporation was during advanced level of colonizing a new planet, the perfect source of strategic metarials. The group of engineers, miners, technicians and their families meant to be the seed of a new civilization. And then one day a … If you enjoyed this game, see our list of games similar to Infectra.

Build your own cardboard fort and defend it against swarms of enemies. Gather resources, craft weapons and set traps. Be creative, improvise and experiment to win. If you enjoyed this game, see our list of games similar to Cartonfall: Fortress.

81%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

84% User Score Based on 3,600 reviews

Critic Score 61%Based on 1 reviews

A necromancer simulator. Assemble the dead using different body parts while upgrading your tower, combine the abilities of the different fantastic races to fight your way through the hordes of enemies and overrun the ’chosen ones’. To tell the truth, the dead are pretty, uhm, dumb. If you enjoyed this game, see our list of games similar to Necrosmith.

53%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:grinding, story

100% User Score Based on 4 reviews

Free layout 3D tower defense war game. There are tanks and Titans on land, battleships and swarms in the sky, and missiles in space. In the face of the enemy, your weapons are not only machine guns, cannons, rockets, but also lasers, cruise missiles and interceptor satellites. If you enjoyed this game, see our list of games similar to War Beasts.

93%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:music, replayability

93% User Score Based on 183 reviews

Build your base. Construct towers, traps, mechs, and other defenses. Command your units in battle. Can you survive the enemy onslaught? If you enjoyed this game, see our list of games similar to Colony Siege.

84%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

84% User Score Based on 1,214 reviews

Critic Score 85%Based on 2 reviews

"You are outgunned. You are massively outnumbered. You must win." These are your orders. Humanity has already fought its war against the machines -- and lost. AI death squads stand watch over every planet and every wormhole, the few remaining human settlements are held captive in orbiting bubbles, and the AIs have turned their attention outward, away from the galaxy, to alien threats or opportuni… If you enjoyed this game, see our list of games similar to AI War: Fleet Command.

68%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:music, story

68% User Score Based on 82 reviews

Seize power and build an empire of fuzzy cellular automata monsters! Herd hundreds of mindless subjects to smash your rivals' castles and steal their territory in this RTS inspired by Conway's Game of Life. If you enjoyed this game, see our list of games similar to Automata Empire.

80%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:replayability, grinding

80% User Score Based on 523 reviews

Join the wonderful and amazing world of microorganisms. If you enjoyed this game, see our list of games similar to Microcosmum: survival of cells.