Games like Tower defense for virus

93%Game Brain Score

Most mentioned positive aspects:monetization, graphics

Most mentioned negative aspects:grinding

93% User Score Based on 2,599 reviews

Build, upgrade and defend in this action-packed offline tower defence If you enjoyed this game, see our list of games similar to 2112TD: Tower Defense Survival.

83%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, grinding

83% User Score Based on 861 reviews

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core! When the aliens swarm your maze and everything seems lost, use active abilities like Air Strike and Freeze to tilt the battlefield to your advantage. If you enjoyed this game, see our list of games similar to Super Sanctum TD.

77%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:music, story

77% User Score Based on 233 reviews

A roguelike tower defense game with a dash of deckbuilding. If you enjoyed this game, see our list of games similar to Core Defense.

95%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, grinding

95% User Score Based on 980 reviews

Defend your dungeon with powerful traps against the greedy adventurers! If you enjoyed this game, see our list of games similar to Dungeon Warfare.

76%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

83% User Score Based on 1,472 reviews

Critic Score 55%Based on 3 reviews

Space Run is a PC game that mixes strategy and space ship construction in real time, borrowing certain mechanics from the “tower defense” system with numerous twists and hyper dynamic gameplay. Space Run is a nod to ‘80s science fiction and pays homage to many of its tropes and references. If you enjoyed this game, see our list of games similar to Space Run.

77%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story

84% User Score Based on 43 reviews

Keep Defending is a first-person VR tower defense archery game where you build up your defenses during the enemy onslaught. Target enemies before they reach your gate and earn gold to set up ever more capable defenses including crossbows, wizards, knights, cannons, and more. Additional Ambush and Advance scenarios present alternative challenges in this growing VR experience. If you enjoyed this game, see our list of games similar to Keep Defending.

Introducing Crystal Guard TD, a dynamic twist on tower defense! Make strategic choices in a shop where you're presented with three randomly selected tower options. Spend wisely and combine three identical towers to level them up. Features 20 different towers to try 25+ different Power ups Pixel graphics In-game tutorial slides 6 Levels to complete Your mission? Defend your crystal shri… If you enjoyed this game, see our list of games similar to Crystal Guard TD.

82%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:music, grinding

82% User Score Based on 149 reviews

All Aboard! The Train Defense Express is out now! 8/07/2025 Update: v1.1.1Patch notes: itch.io | Steam Now available on mobile!Google Play (Android)Apple App Store (iOS) All Aboard! is a mix between auto-battler, survivor, tower defense, and idle/clicker games. The goal is to protect the central objective, the Infinite Power Generator, from endlessly spawning hordes of enemies, and to see how l… If you enjoyed this game, see our list of games similar to All Aboard! The Train Defense Express.

66%Game Brain Score

Most mentioned positive aspects:gameplay

Most mentioned negative aspects:music, story

76% User Score Based on 38 reviews

Stronghold Defenders is a Tower Defense game with a twist. Unlike normal Tower Defense games, you have gathering units and resources to manage as well as your defending units that are used to attack enemies.  This adds another strategy layer to the game where you have to make decisions every turn on what resources you want to gather and if you want to recruit a defender or a gatherer.  You also ne… If you enjoyed this game, see our list of games similar to Stronghold Defenders.

95%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, grinding

95% User Score Based on 1,107 reviews

Utopia Must Fall is a vector-flavored base-defending arcade shooter with rapid progression, procedurally generated attack waves and enough upgrade variety to suit both the defensive or aggressive player.It incorporates elements from tower defense, roguelites and beyond, all neatly packaged into a laser-sharp bullet-purgatory arcade frenzy! Features Easy To Learn: firing happens automatically, just… If you enjoyed this game, see our list of games similar to Utopia Must Fall.

97%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:stability, grinding

97% User Score Based on 2,360 reviews

Emberward is a unique tower defense game that focuses on maze building and interesting tower mechanics. Construct mazes with blocks of different shapes and set up defense towers on them to withstand the onslaught of monsters! If you enjoyed this game, see our list of games similar to Emberward.

87%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:story, optimization

87% User Score Based on 76 reviews

Acid Planet is a Tower-Defense game with elements of Horde-Survival, Action Roguelike, and RTS. It's a game for people who like building, strategy, tactics and epic automated sci-fi battles. Drop to the surface, lure in the horde and bag the biggest kaiju you can handle. BUILD YOUR BASEConstruct towers and drone factories to defend your ship from the horde. Make use of the environment - strategic … If you enjoyed this game, see our list of games similar to Acid Planet.

88%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, story

88% User Score Based on 586 reviews

Tower Factory is a game where you have to build a factory that allows you to create enough towers to defend yourself from enemies. You'll need to find and destroy the enemy castle before it becomes too powerful and its monsters overwhelm you! Features: Constantly build, expand, and upgrade your factory. Acquire resources to build more and better towers. Explore the map to locate the enemy castle, … If you enjoyed this game, see our list of games similar to Tower Factory.

87%Game Brain Score

Most mentioned positive aspects:graphics, story

Most mentioned negative aspects:monetization, stability

87% User Score Based on 9,987 reviews

Human tactics vs. zombie hordes. If you enjoyed this game, see our list of games similar to Zombie Defense.

41%Game Brain Score

Most mentioned positive aspects:story, music

Most mentioned negative aspects:gameplay, graphics

70% User Score Based on 10 reviews

Starlight: Defence Command is a Tower Defence game designed for the PC that is tough and more in-depth than those gone before. With the ability to configure towers in billions of possible combinations, unlockable perks and fine tuning through target priorities, players are given powerful tools to complete the galaxy-spanning, story-driven campaign. If you enjoyed this game, see our list of games similar to Starlight: Defence Command.

76%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, story

83% User Score Based on 590 reviews

Critic Score 40%Based on 1 reviews

Over 9000 Zombies! is top-down arcade action blown out of all reasonable proportions. An endless horde of zombies is coming your way, how long can you survive? If you enjoyed this game, see our list of games similar to Over 9000 Zombies!.

84%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:optimization, grinding

84% User Score Based on 578 reviews

Fend off hordes of enemies in this arcade tower defense roguelite with autobattler elements. Build up a team of powerful synergies and become unstoppable. If you enjoyed this game, see our list of games similar to FLERP.

80%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:grinding, stability

81% User Score Based on 877 reviews

Critic Score 78%Based on 2 reviews

Tower defense game with a 50-level campaign across 5 worlds. If you enjoyed this game, see our list of games similar to Revenge of the Titans.

90%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding, stability

90% User Score Based on 831 reviews

Tower Tactics: Liberation fuses deck-building games and roguelikes to modernize the tower defense genre like never before - make your way through procedurally generated maps, collect valuable trinkets and manage your arsenal to defend yourself against the Salkoth! If you enjoyed this game, see our list of games similar to Tower Tactics: Liberation.

58%Game Brain Score

Most mentioned positive aspects:gameplay

93% User Score Based on 14 reviews

Defense of the Dauntless is an endless horde mode tower defense game with roguelite progression. Build your Defenses, your Way Let your creativity and ingenuity guide where you place your towers and walls. Anything goes! Defend and Reinforce your Stronghold As you defeat the hordes you'll earn reinforcements. These timely bonuses could give you some much needed gold, stun enemies, unlock new … If you enjoyed this game, see our list of games similar to Defense of the Dauntless.

61%Game Brain Score

Most mentioned positive aspects:music

Most mentioned negative aspects:graphics

100% User Score Based on 12 reviews

Embark on a strategic adventure in the mystical medieval world of Beyond The Walls, a 3D tower defense game that challenges you to master elemental warfare and town management. Unique Elemental Defense System At the core of Beyond The Walls, lies a distinctive elemental tower system featuring six core elements. Start with a single element and strategically integrate others as you upgrade your tow… If you enjoyed this game, see our list of games similar to Beyond The Walls.

45%Game Brain Score

Most mentioned positive aspects:graphics, story

Most mentioned negative aspects:gameplay, replayability

64% User Score Based on 22 reviews

Stonehold is a 2D rogue-lite tower defense. Survive waves of enemies, upgrade your power in real time, and grow stronger after every run. If you enjoyed this game, see our list of games similar to Stonehold.

98%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

98% User Score Based on 122 reviews

Dear Magical Girls is a story-driven defense game about an overworked magical girl protecting the Mana Stone that keeps the city running. Move the vertices to reshape your magical field. Unlock modules and enchants, and build your own strategy to survive against waves of monsters. If you enjoyed this game, see our list of games similar to Dear Magical Girls.

69%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, replayability

69% User Score Based on 404 reviews

Critic Score 71%Based on 2 reviews

Necronator: Dead Wrong is a comedic micro RTS game with a deck-building twist. Collect and deploy undead units and build an army to conquer the insufferable goody-two-shoes of the Livmor Alliance. Raise the dead, drop the mic. Those instructors at the Undead Academy don't understand your talent. Why trudge your way through years of training... when you could just make a deal with an evil ancient … If you enjoyed this game, see our list of games similar to Necronator: Dead Wrong.

70%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:story, graphics

100% User Score Based on 21 reviews

Dawnhold is a top-down action base-defense game where you gather resources, build up your defenses, and survive relentless enemy waves. Strike back by assaulting enemy strongholds and defeating powerful bosses in a fight to protect the Sunstone. If you enjoyed this game, see our list of games similar to Dawnhold.

86%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

86% User Score Based on 865 reviews

Welcome to Drill Core, where corporate greed meets strategic planet-mining! By day, lead an elite crew of miners, carriers, and guards as they carve a path through hostile alien worlds. Build advanced facilities, upgrade deadly turrets, and prepare for relentless nightly assaults from alien lifeforms. Will you chase maximum efficiency at any cost, or play it safe and fight to survive? Drill Core i… If you enjoyed this game, see our list of games similar to Drill Core.

85%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:replayability, story

85% User Score Based on 170 reviews

Repel the Rifts is a roguelite tower defense game set on an alien world. As a Commander of a mining expedition gone awry, you must defend against relentless waves of inter-dimensional creatures emerging from mysterious rifts. Progress your expedition, survey further into the unknown and track down the source of the rifts. Key Features Survey the UnknownEvery other day, survey the unknown to ex… If you enjoyed this game, see our list of games similar to Repel the Rifts.

88%Game Brain Score

Most mentioned positive aspects:graphics, story

Most mentioned negative aspects:monetization, grinding

88% User Score Based on 4,980 reviews

A unique TD RPG game with customizable heroes wielding powerful skills and gear! If you enjoyed this game, see our list of games similar to Last Hope TD - Tower Defense.

89%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

89% User Score Based on 154 reviews

A roguelike royalelike about warriors from across space and time, fighting to claim a wish from the Star of Aestheta. Strategize your tactics, enhance your troops, and outwit your opponents to rise to the top! If you enjoyed this game, see our list of games similar to Aestheta.

80%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, monetization

80% User Score Based on 293 reviews

Explosive singleplayer action RTS with a story campaign. Hold the line against massive swarms on a fully simulated battlefield. If you enjoyed this game, see our list of games similar to IDUN.

74%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:stability, story

74% User Score Based on 462 reviews

Live real time battle, micromanagement and survive the battle with your army of your chosen, Live with mayhem and explosions. If you enjoyed this game, see our list of games similar to Northend Tower Defense.

92%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, stability

92% User Score Based on 142 reviews

Defend humanity's last hope, pilot a powerful mech, in Frontlines Crisis! A battlefield swarming with insects makes strategic and combat decisions crucial. Each decision will determine your fate. Defend humanity's last sanctuary, fight fiercely, and uphold human honor with wits and courage! If you enjoyed this game, see our list of games similar to Frontline Crisis.

62%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

79% User Score Based on 29 reviews

The Zombees are coming, and there's only one way to protect the hive:  Build towers of massive BEE-listic power reinforced by upgrades that make them even more threatening. Unlock different queen bees with unique abilities from seasonal spells to advanced technology. Burn, explode, and electrocute hordes of zombie bees until you eradicate them or until your hive succumbs to the inevitable zumbe… If you enjoyed this game, see our list of games similar to Bees vs Zombees.

83%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

83% User Score Based on 266 reviews

You! the most outstanding pioneer who graduated from this kingdom, are finally about to embark on your legendary journey. Construct towns across various levels to fend off waves of attacks from diverse enemies until you establish a firm footing and complete your exploration! Build your own mini town Expand progressively on the barren map, construct a complete town, and uncover rarer buildings an… If you enjoyed this game, see our list of games similar to Border Pioneer.

81%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

84% User Score Based on 3,600 reviews

Critic Score 61%Based on 1 reviews

A necromancer simulator. Assemble the dead using different body parts while upgrading your tower, combine the abilities of the different fantastic races to fight your way through the hordes of enemies and overrun the ’chosen ones’. To tell the truth, the dead are pretty, uhm, dumb. If you enjoyed this game, see our list of games similar to Necrosmith.

93%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:grinding, story

93% User Score Based on 1,168 reviews

Create an army and use spells while it fights for you. Mage & Monsters is a strategic battler, where you must choose wisely between upgrading the might of your army, or increasing the power of your spells. If you enjoyed this game, see our list of games similar to Mage and Monsters.

83%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

83% User Score Based on 1,748 reviews

Critic Score 83%Based on 5 reviews

Anomaly Warzone Earth is an extraordinary mixture of action and strategy in a reversed tower defense formula. The game tasks you with saving a near-future Earth from an alien onslaught. The invaders have captured several of the world’s major cities, building huge turrets that destroy everything in their path. It’s up to you to lead an armor squad through the streets of cities like Baghdad and Toky… If you enjoyed this game, see our list of games similar to Anomaly: Warzone Earth.

62%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

62% User Score Based on 678 reviews

"Infectonator : Survivors" is a Randomized Permadeath Survival Simulator that combines RTS, Tower Defense, Roguelike, and Management-Simulation gameplay. The goal is to lead a group of survivors in a struggle to stay alive and find rescue in a zombie apocalyptic world. You must scavenge resources, build defenses, and find a way to survive in a game where death is permanent and levels are randomly … If you enjoyed this game, see our list of games similar to Infectonator: Survivors.

88%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:atmosphere, grinding

91% User Score Based on 574 reviews

Critic Score 80%Based on 4 reviews

Cannon Brawl is a 2D action strategy game with big explosions and destructible terrain. Command the action from your airship to build cannons, capture mines, expand your territory and more. Choose from a multitude of buildings, cannons and towers to assemble a force that will rain destruction from the sky and defeat your enemy! Advance your military campaign across the map in single player mode, o… If you enjoyed this game, see our list of games similar to Cannon Brawl.

87%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, optimization

87% User Score Based on 248 reviews

Clean a galaxies from thousands of invaders! Nebula is an action, space shooter where your choices are making you progressively stronger against the endless waves of space enemies. If you enjoyed this game, see our list of games similar to Nebula.

77%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:story, stability

77% User Score Based on 254 reviews

A space station builder simulation roguelite. Fight off enemy ships, fleets and rival stations, build and upgrade your station, hire and manage your crew. Survive as long as you can. If you enjoyed this game, see our list of games similar to Rogue Station.

95%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, story

95% User Score Based on 93 reviews

Bullet Hell Insanity + Tower Defense Strategy. Rogue Star Rescue is a quirky new type of rogue-like shooter. Blast your way through diverse planets while rescuing your teammates and gathering traps for your defense strategy. If you enjoyed this game, see our list of games similar to Rogue Star Rescue.

89%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:graphics, story

89% User Score Based on 124 reviews

Chess Survivors is a grid based, quick-turn, roguelike where you outmaneuver and destroy an ever growing horde of chess enemies. Combine abilities and upgrades to create game-breaking builds. Unlock cosmetics, characters, and powerful relics. Think fast, die, learn, repeat. If you enjoyed this game, see our list of games similar to Chess Survivors.

83%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:optimization, grinding

83% User Score Based on 1,103 reviews

Rocked by an explosive soundtrack, choose your band, place your equipments and defend the Rock 'N' Roll from everyone and everything who try to pull it down, on a totally hardcore tower defense! If you enjoyed this game, see our list of games similar to Rock 'N' Roll Defense.

74%Game Brain Score

Most mentioned positive aspects:graphics, story

Most mentioned negative aspects:stability, grinding

83% User Score Based on 9,278 reviews

Critic Score 30%Based on 1 reviews

MILLIONS OF ALIENS WILL DIE If you enjoyed this game, see our list of games similar to Radiant Defense.

Overview: Brace yourself for an epic battle of brains and firepower in Doomsday Tower Defense, a fast-paced and strategic top-down game blending action, simulation, and strategy. With colorful 2D visuals and a dark, thrilling atmosphere, players must defend humanity's last stronghold against endless waves of zombies. Build, strategize, and manage resources to outwit and outlast the zombie apocalyp… If you enjoyed this game, see our list of games similar to Doomsday Tower Defense.

Pullstation is an incremental tower defence about saving your space station from the ever-growing horde of UNKNOWN origin. If you enjoyed this game, see our list of games similar to Pullstation.

94%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:character development, monetization

94% User Score Based on 69 reviews

Antivirus Girl is a defense shooter game where you become an inspector for the anti-malware Sentinel to protect computers from malware. Inspect files coming in from the network, let safe files pass through, and immediately eliminate malware. If you enjoyed this game, see our list of games similar to Antivirus Girl.

65%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:music, story

85% User Score Based on 27 reviews

Cosmic Raze is a sci-fi tower defense strategy game set in the near future, at the dawn of an alien invasion. Take control of advanced weapon systems, build powerful synergies, and then blast away as aliens attempt to conquer Earth. Between rounds you'll earn unique augmentations, purchase and upgrade a huge variety of weapons, make scientific breakthroughs, and unlock powerful synergy bonuses. … If you enjoyed this game, see our list of games similar to Cosmic Raze.

83%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, replayability

83% User Score Based on 113 reviews

castle idler is a short, relaxing incremental tower defense game with no waves. upgrade towers, collect coins, and unlock powerful prestige upgrades to defend your castle. If you enjoyed this game, see our list of games similar to castle idler.