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Symptoms of Infection

Symptoms of Infection Game Cover
85%Game Brain Score
Most mentioned positive aspects:atmosphere, graphics
Most mentioned negative aspects:gameplay, music
89% User Score Based on 46 reviews

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Symptoms of Infection Game Cover

About Symptoms of Infection

Symptoms of Infection is a single player simulation game with a horror theme. It was developed by ORB Research & Broadcasting and was released on June 28, 2026. It received positive reviews from players.

Help discover novel and chimeric pathogens and treat the strange, sometimes horrifying, infectious diseases they produce. Examine and test patients for common and novel infections using sophisticated medical instrumentation and disinfection procedures. All infected patients must be sent to the isolation ward for further evaluation and treatment. Rumors of mysterious diseases and human experimenta…

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Symptoms of Infection screenshot
Symptoms of Infection screenshot
Symptoms of Infection screenshot
Symptoms of Infection screenshot
Symptoms of Infection screenshot
Symptoms of Infection screenshot
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Reviews

89%Audience ScoreBased on 46 reviews
atmosphere8 positive mentions
gameplay3 negative mentions
  • The game creates a highly engaging and unsettling horror atmosphere with 8-bit retro graphics and an effective sound design that evokes a lost early PC-era software vibe.
  • It offers a unique and intriguing concept reminiscent of classic DOS games, with a dark narrative that provokes curiosity and a sense of dread without relying on jump scares.
  • The game demonstrates strong potential with thoughtful direction and dedication from developers, including callbacks to similar retro games, and has players eager for additional content and expansions.
  • Gameplay is overly linear and restrictive, with little actual choice or freedom; players cannot make mistakes or experience consequences, which diminishes immersion and replayability.
  • The current content is very limited, resulting in a short playtime with repetitive patient scenarios and insufficient diversity in symptoms, infections, and narrative depth.
  • Technical issues include lack of reliable save system and occasional crashes, which frustrate progress since the experience must often be replayed from the start to see different outcomes.

  • atmosphere

    8 mentions Positive Neutral Negative
    100% positive mentions, 0% neutral mentions, 0% negative mentions

    The game's atmosphere is consistently praised for its intense, immersive quality, enhanced by 8-bit graphics and sound design. Reviewers find it both simple and terrifying, creating a strong ambience that greatly contributes to the overall experience despite the game's short length.

    • “Otherwise, I really enjoyed the atmosphere which is intensified by 8-bit graphics and sound design.”
    • “Aside from quality of life things like that, I like the atmosphere, the premise, the ambience, the art and the cold-start intro.”
    • “A very short but enjoyable game that has atmosphere to the nines.”

  • graphics

    7 mentions Positive Neutral Negative
    43% positive mentions, 57% neutral mentions, 0% negative mentions

    The game's 8-bit, low-fidelity graphics effectively enhance the atmosphere and body horror aesthetic, creating a unique and immersive experience. The art style is praised for its creativity, though some users note the need for sound options to complement the visuals. Overall, the graphics successfully balance scariness with imagination.

    • “Otherwise I really enjoyed the atmosphere which is intensified by 8-bit graphics and sound design.”
    • “The low-fidelity graphics give you just enough to be scary while also letting your imagination fill in the gaps for things that you can't see too clearly.”
    • “You really nailed the aesthetics.”

  • story

    6 mentions Positive Neutral Negative
    50% positive mentions, 50% neutral mentions, 0% negative mentions

    The story is intriguing and unsettling, involving a mysterious patient and connected elements that have piqued players' curiosity. It successfully captivates players, prompting interest in deeper explanations and potential expansions within the overarching narrative.

    • “I'm very curious now about the storyline and any connected projects, how it all may come together.”
    • “This is a brief game connected to a ghost of an ARG story, and one that had my friends and me enraptured until the very end of the game.”
    • “I'd love to hear a deeper explanation of the ARG story, if you'd be willing to share.”

  • gameplay

    5 mentions Positive Neutral Negative
    40% positive mentions, 0% neutral mentions, 60% negative mentions

    The gameplay features an intriguing concept with time pressure and infection progression adding tension, but it is criticized for being too linear and heavily scripted with limited player agency. Some mechanics lack clear explanation, and players desire less handholding and more meaningful choices, including the possibility of making wrong diagnoses. Overall, while conceptually strong, the gameplay feels more like a guided narrative with minimal interactivity.

    • “A good amount of mysteries, big fan of the way it looks (big mortis guy, you know). My main/only gripe gameplay-wise is that I kinda wish I could get the diagnosis wrong or there was less handholding, but the time pressure and infection progression mechanic was so cool I didn't mind. Played through again, taking my time, making different choices and letting some infections progress. This is sick, no pun intended. I'm still wondering if the 'choose room for the transfer' bit has any impact, as I was trying to consider that and remember who was where.”
    • “Cool concept and gameplay mechanics.”
    • “That being said, there is very little actual gameplay beyond tightly scripted events that almost universally have the same outcome, and very little room for error, as the game plays, to this point at least, as a 'click to see what happens next' kind of thing.”
    • “I like it conceptually but I really don't like how linear the gameplay is.”
    • “Examination phase feels a little too 'on-rails' however, and some mechanics could do with a bit more explanation.”

  • music

    1 mentions Positive Neutral Negative
    0% positive mentions, 0% neutral mentions, 100% negative mentions

    The game features minimal or absent music, which enhances the uneasy atmosphere by emphasizing the focus on patients and the unknown.

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Frequently Asked Questions

Symptoms of Infection is a simulation game with horror theme. Common tags for Symptoms of Infection include surreal, psychological, life sim, pixel graphics, psychological horror and others.

Symptoms of Infection is available on PC, Windows and Linux.

Symptoms of Infection was released on June 28, 2026.

Symptoms of Infection was developed by ORB Research & Broadcasting.

Symptoms of Infection has received positive reviews from players. Most players liked Symptoms of Infection for its atmosphere but disliked it for its gameplay.

Symptoms of Infection is a single player game.

Similar games include No I'm not a Human, The Complex: Expedition, Reminiscence, Last Report, DEAD LETTER DEPT. and others.