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Symptoms of Infection Game Cover

About Symptoms of Infection

Symptoms of Infection is a single player simulation game with a horror theme. It was developed by ORB Research & Broadcasting and was released on June 28, 2026. It received positive reviews from players.

THE ADVANCED PROGRAMNEW IN SYMPTOMS OF INFECTION: THE ADVANCED PROGRAM Diagnosis and treatment; revisit patients at your discretion New diseases and unique patients A mystery hidden in the PSYCHIATRIC WARD Ability to use different IV medications and treatments; M.D.T. (experimental treatment) Improved CELLULAR INTERVENTION soft-ware module Psychotherapy, clinical trials, tests, audit, …

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Looking for games like Symptoms of Infection? Here are top simulation recommendations with a horror focus, selected from player-similarity data — start with No I'm not a Human, Last Report or The Mortuary Assistant.

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Reviews

90%Audience ScoreBased on 58 reviews
atmosphere8 positive mentions

  • Exceptional atmosphere and presentation with pixel art and creepy music creating a nostalgic yet eerie feeling.
  • Engaging medical simulation gameplay with accurate procedures and a compelling diagnosis system that introduces interesting illnesses and ethical dilemmas.
  • Intriguing story and mystery elements that encourage replaying and exploring hidden scenarios, supported by developer responsiveness and community interest.
  • Currently very short with limited content, leading to repetitive patient cases and a lack of variety in symptoms and decisions.
  • Gameplay feels too linear and hand-holding, disallowing meaningful mistakes or player-driven diagnosis decisions, reducing the sense of agency.
  • Technical issues such as unclear save system, occasional crashes, and vague mini-games which can cause frustration and force restarts.
  • gameplay

    10 mentions Positive Neutral Negative
    30% positive mentions, 40% neutral mentions, 30% negative mentions

    The gameplay is praised for its accurate, medical training-inspired mechanics and nostalgic retro style, creating an eerie and immersive atmosphere. However, some find it overly linear and on-rails, with limited player agency and minimal room for error, leading to a somewhat scripted experience. Overall, the concept and core mechanics are well-received, though more depth and variability could enhance engagement.

    • “The procedures and gameplay are accurate, and the retro style combined with the chippy audio truly sells the nostalgic yet eerie feeling.”
    • “The story is good, still feels a bit incomplete but I have high hopes for this game. Gameplay-wise it was really good; I love that the game actually feels like a medical training program.”
    • “A good amount of mysteries, big fan of the way it looks (big mortis guy, y'know). My main/only gripe gameplay-wise is that I kinda wish I could get the diagnosis wrong or there was less handholding. But the time pressure and infection progression mechanic was so cool I didn't mind. Playing again and making different choices made the experience even better.”
    • “At this point, it doesn't even feel like a demo, and barely resembles the gameplay and atmosphere they're clearly going for.”
    • “Examination phase feels a little too 'on-rails'; some mechanics could use more explanation.”
    • “There is very little actual gameplay beyond tightly scripted events with almost the same outcome, and very little room for error, making the game feel like a 'click to see what happens next' experience.”
  • atmosphere

    10 mentions Positive Neutral Negative
    80% positive mentions, 10% neutral mentions, 10% negative mentions

    The game's atmosphere is widely praised for its strong immersion, intensified by 8-bit graphics and sound design, creating a simple yet terrifying ambience. Reviewers appreciate the concept and presentation, noting that the atmosphere significantly enhances the overall experience despite the game's brevity.

    • “Otherwise, I really enjoyed the atmosphere, which is intensified by 8-bit graphics and sound design.”
    • “A very short but enjoyable game that has atmosphere to the nines.”
    • “Very good idea, the game atmosphere is simple yet terrifying.”
    • “At this point, it doesn't even feel like a demo, and barely resembles the gameplay and atmosphere they're clearly going for.”
  • story

    9 mentions Positive Neutral Negative
    33% positive mentions, 34% neutral mentions, 33% negative mentions

    The story is praised for its intriguing mystery and choice-driven narrative, though some users feel it currently feels incomplete and hope for expanded endings. Players appreciate the immersive medical training aspect and are curious about deeper connections and underlying stories, especially related to an ARG element. Overall, the story captivates players and leaves them eager for further development and explanation.

    • “I love the mystery in the story, the ability to make choices and 'wrongfully diagnose' patients adds depth. Maybe different endings will be implemented later?”
    • “The story is good, still feels a bit incomplete but I have high hopes for this game. Gameplay-wise it was really good; I love that the game actually feels like a medical training program.”
    • “This is a brief game connected to a ghost of an ARG story, and one that had my friends and me enraptured until the very end of the game.”
    • “There's some kind of story in this game involving a patient, but it lacks depth and clarity.”
    • “The story feels brief and incomplete, leaving many questions unanswered.”
    • “While the mystery is intriguing, the plot progression is unnerving and underdeveloped.”
  • graphics

    7 mentions Positive Neutral Negative
    43% positive mentions, 57% neutral mentions, 0% negative mentions

    The game's 8-bit, low-fidelity graphics effectively enhance its eerie atmosphere and body horror theme, striking a balance between detail and imagination. The art style is praised for its creativity and strong aesthetic appeal, though some users note the need for sound options alongside the visuals. Overall, the graphics are a highlight that significantly contribute to the game's immersive experience.

    • “Otherwise, I really enjoyed the atmosphere which is intensified by 8-bit graphics and sound design.”
    • “You really nailed the aesthetics.”
    • “The low-fidelity graphics give you just enough to be scary while also letting your imagination fill in the gaps for things that you can't see too clearly.”
  • music

    2 mentions Positive Neutral Negative
    50% positive mentions, 0% neutral mentions, 50% negative mentions

    The music effectively enhances the game's eerie atmosphere, complementing the pixel art to create a creepy and unsettling ambiance. Its simplicity and occasional absence contribute to a sense of discomfort and mystery surrounding the players and the unknown.

    • “It has a wonderful ambiance: the pixel art does an excellent job at conveying the setting and what the game is about, as does the music; even in its simplicity, it grants a general creepiness to everything.”
    • “Lack of music, focus on patients and the unknown made it pretty uncomfortable.”
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Frequently Asked Questions

Symptoms of Infection is a simulation game with horror theme. Common tags for Symptoms of Infection include surreal, psychological, life sim, pixel graphics, psychological horror and others.

Symptoms of Infection is available on PC, Windows and Linux.

Symptoms of Infection was released on June 28, 2026.

Symptoms of Infection was developed by ORB Research & Broadcasting.

Symptoms of Infection has received positive reviews from players. Most players liked Symptoms of Infection for its atmosphere but disliked it for its gameplay.

Symptoms of Infection is a single player game.

Similar games include No I'm not a Human, Last Report, The Mortuary Assistant, DEAD LETTER DEPT., TELEFORUM and others.