Games like Powerhouse of The Immune System

61%Game Brain Score

Most mentioned positive aspects:music, story

100% User Score Based on 12 reviews

Listeria Wars is a tactical strategy where we protect the hero’s body from various infections and viruses by controlling the troops of the immune system. We can observe his personal life and even influence it with side effects. If you enjoyed this game, see our list of games similar to Listeria Wars.

Game Play SummaryThe Crafter’s Defense is an action-defense game, combining elements of both tower defense and action games. The player takes on the role of a dungeon core, a human reincarnated as a sentient dungeon, and must defend against waves of invaders. In place of towers, players place traps and dungeon monsters which can be placed directly on the invasion path, where they can attack the in… If you enjoyed this game, see our list of games similar to The Crafter's Defense.

Defend the body in vaXinator, a fast-paced action roguelike! As the last white blood cell, unleash powerful abilities and antibodies to fight off waves of infections. Test your reflexes in this microscopic battle for survival. How long can you hold the line? If you enjoyed this game, see our list of games similar to vaXinator.

51%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, music

56% User Score Based on 43 reviews

Prophour23 is a fast-paced, replayable real-time strategy. It's designed for short, quick plays. A single playthrough will take you about 15 minutes, if you're good. But the next one will be different. And another one as well. If you enjoyed this game, see our list of games similar to Prophour23.

Metacell: Genesis ARCADE is an arcade game inspired by old-school arcade games, with the match 3 mechanic. The basic gist of Arcade mode is a score attack mechanic where you want to survive to level 100 with the highest score. Fight back a never ending spawn of game pieces by making matches of 3 or more before the board fills up, or even worse, you are killed by one of the traps that could spawn a… If you enjoyed this game, see our list of games similar to Metacell: Genesis ARCADE.

What The Fortress!? is surprisingly a tower defense game, but with some twists! You can modify the layout of the map, plan the paths of the incoming enemies, and research dozens of upgrades and towers.Be a real road architectYou have complete control over the map. Carve the path of your enemies, set deadly traps like Ice, Water or Magma tiles. You won't only build towers, but construct the ways be… If you enjoyed this game, see our list of games similar to What The Fortress!?.

97%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, monetization

97% User Score Based on 15,544 reviews

A minimalist game about building and defending a little kingdom. Thronefall is a classic strategy game without unnecessary complexity, just some healthy hack-and-slay. Build up your base during the day, and defend it ‘til your last breath at night. If you enjoyed this game, see our list of games similar to Thronefall.

Escape From The Red Planet is a tower defence game that puts you in the shoes of Commander Abigail Blackwell of The Orion III. After a crash landing that left you stranded on Mars, you must employ serious resource management to keep yourself safe from incoming Martian attacks. While you wait for rescue, keep your solar batteries charged to build up your attack and defence. KEY FEATURES - Three di… If you enjoyed this game, see our list of games similar to Escape From The Red Planet.

74%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:replayability, stability

74% User Score Based on 231 reviews

Risen Kingdom is a real-time strategy game with building and settlement management mechanics. The game is set in a medieval fantasy world years after a great Kingdom has been overrun by hordes of the undead. Now, the bravest warriors are going on a campaign to claim back the land once lost by their ancestors and bring the Kingdom back to its former glory. If you enjoyed this game, see our list of games similar to Risen Kingdom.

86%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:stability, grinding

91% User Score Based on 7,467 reviews

Critic Score 81%Based on 11 reviews

BUILD, EXPLORE, DEFEND, CONQUER If you enjoyed this game, see our list of games similar to Kingdom: Classic.

97%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, music

97% User Score Based on 226 reviews

Check out the updated version on Steam here! The world is under siege from an unknown enemy. Gates are appearing, spawning demonic entities. Major cities have been destroyed with overwhelming force. Most of the population has been decimated, but the dead rise again to feast on the living. There was no warning, no signs, no dark omen... Just death and destruction. This is the apocalypse. There are… If you enjoyed this game, see our list of games similar to Endgame: Road To Salvation.

"Reverse tower defense" game, or maybe "snake with enemies". Lead small groups of creatures through guard towers defense.  Control using keyboards. This is a demo of Protolife: Other Side game released on Steam. This demo includes a tutorial and the first zone only. If you enjoyed this game, see our list of games similar to Protolife: Other Side.

Mitosis Mercenary - Cell Wars Jam Game Jam Entry for Trijam #354 You are a white blood cell warrior. Defend the body against an endless onslaught of viruses, bacteria, and other pathogens. Grow stronger through mitosis, collect powerful upgrades, and survive the final wave to achieve victory! Can you grow strong enough to survive the final wave? About the Game Mitosis Mercenary is a top-dow… If you enjoyed this game, see our list of games similar to Mitosis Mercenary.

If the game has piqued your interest, please don't hesitate to try the demo. You can also access the demo on Steam. You can take a look at our game's Steam page below and make me very happy by adding FarmTech to your WISHLIST. Thank you for your support Steam  https://store.steampowered.com/app/2361500/FarmTech/ FARMTECH In this world taken over by aliens, you have been given a special mis… If you enjoyed this game, see our list of games similar to FarmTech.

69%Game Brain Score

Most mentioned positive aspects:gameplay, music

100% User Score Based on 20 reviews

Can you build and fight through endless levels to bring life and color to your world? Customize towers and troops to ward off enemies in this fast-paced and colorful tower defense. If you enjoyed this game, see our list of games similar to HexeD.

Lead survivors out of 20 different complex mazes while quarantining or curing the infected in this fun puzzle game that's sure to test every ounce of your mental skills. Get close and personal by playing not only from above in 2D but also in 3D as you scour every inch of the maze for the best possible route. If you enjoyed this game, see our list of games similar to Zombie Quarantine.

Stranded in another solar system on a confusing planet, you must source fuel for your ship. You'll learn how to research, build and defend in increasingly hostile scenarios across the planet. Hive tasks you with mastering three components of colonisation: - Agriculture: providing food to your structures to boost their productivity, - Industry: mining resources and refining them, - Defence: preve… If you enjoyed this game, see our list of games similar to Hive.

85%Game Brain Score

Most mentioned positive aspects:music, gameplay

85% User Score Based on 82 reviews

The greatest gameshow on earth is here with breakneck speed, bullet dodging action and lots of guns. Put it all on the line for the (rogue)likes. And remember, the run is all that matters. If you enjoyed this game, see our list of games similar to DEATHRUN TV.

70%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

70% User Score Based on 166 reviews

Roadmap About the GameKingdom's Deck is a game about survival and growing your kingdom. As the ruler of the land, you must navigate the challenges of staying alive, taking care of your people's requirements, building a powerful army, and protecting your fort from approaching threats Step into the role of the king, entrusted with the fate of an entire realm. Your journey is guided by your co… If you enjoyed this game, see our list of games similar to Kingdom's Deck.

78%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

78% User Score Based on 301 reviews

Black Forest is a single-player, real-time strategy city builder like no other. Where other games focus on expansion and development, Black Forest is all about defending what's yours. Strategically assign villagers, gather resources, reinforce defenses, and above all, maintain the delicate balance until the king's knights arrive. If you enjoyed this game, see our list of games similar to Black Forest.

52%Game Brain Score

Most mentioned positive aspects:gameplay

Most mentioned negative aspects:graphics, music

100% User Score Based on 3 reviews

Previously $5.00, the price has been reduced 80% to $0.99! The anti-strategy game for unconventional humans. Grand Attrition is an RTS/tower defense survival game with RPG elements that boasts innovative game mechanics where you can take control of everything in battles, from map terrain to enemy units. Combine a wide variety of playable units, side grades, and talents to ensure no battle is th… If you enjoyed this game, see our list of games similar to Grand Attrition.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:optimization, story

91% User Score Based on 1,015 reviews

Thrive is a free, open-source game about the evolution of life. From the lowly tidepools of your home planet, you will rise to cosmic dominance. At every step, powerful creation tools and deep simulation mechanics will aid your species' development. If you enjoyed this game, see our list of games similar to Thrive.

75%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, music

75% User Score Based on 478 reviews

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy. If you enjoyed this game, see our list of games similar to Defend Your Life: TD.

61%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

61% User Score Based on 190 reviews

‘Alien Marauder’ is a real-time strategy game with survival and confrontation theme.In this game, you will be the leader to a treacherous alien planet, get all kinds of supplies to build your outpost, and deploy troops to resist the incoming vexans strategically! If you enjoyed this game, see our list of games similar to Alien Marauder.

83%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

86% User Score Based on 7,734 reviews

Critic Score 83%Based on 5 reviews

Mystery to discover, darkness to conquer. A noio and Raw Fury game. If you enjoyed this game, see our list of games similar to Kingdom: New Lands.

82%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

88% User Score Based on 9,193 reviews

Critic Score 60%Based on 14 reviews

BUILD, EXPLORE, DEFEND, CONQUER If you enjoyed this game, see our list of games similar to Kingdom: Classic.

67%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

69% User Score Based on 127 reviews

Critic Score 60%Based on 1 reviews

An action-farming-roguelite, full of whimsical flora and mischievous creatures that really want to ruin your dark and mysterious plans of… Going vegan! If you enjoyed this game, see our list of games similar to Voltaire The Vegan Vampire.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story

91% User Score Based on 70 reviews

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time! If you enjoyed this game, see our list of games similar to Life on the Edge.

83%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

Most mentioned negative aspects:graphics, stability

83% User Score Based on 263 reviews

Castle Craft is a game where players can build huge castles in an ancient wartorn world and must defend them against hordes of enemies in siege battles of epic proportions. Castle Craft is a unique blend of the voxel sandbox genre, action, and tower defense. If you enjoyed this game, see our list of games similar to Castle Craft.

29%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:optimization, gameplay

46% User Score Based on 13 reviews

AVAILABLE NOW IN EARLY ACCESS Final Stand: Ragnarök pits you and up to seven players against the forces of Hel, teaming up in a Co-Op Hero Action-Slasher against wave after wave of thousands of the goddess of death's devious minions, in large-scale, real-time battles powered by the proprietary and revolutionary Unchained Engine. As the game progresses through Early Access we will be gradually ad… If you enjoyed this game, see our list of games similar to Final Stand: Ragnarök.

76%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, story

83% User Score Based on 590 reviews

Critic Score 40%Based on 1 reviews

Over 9000 Zombies! is top-down arcade action blown out of all reasonable proportions. An endless horde of zombies is coming your way, how long can you survive? If you enjoyed this game, see our list of games similar to Over 9000 Zombies!.

66%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:optimization, stability

66% User Score Based on 293 reviews

Beneath the Mountain is a dwarven city-builder and real-time-strategy game. Mine your way into the mountain, discover gold and silver, construct buildings, recruit an army, build traps, and defeat the vile creatures that lurk in the dark caves of the mountain. Most importantly, find the heart of the mountain before the orcs destroy your kingdom. Beneath the Mountain is a top-down, isometric, 3D … If you enjoyed this game, see our list of games similar to Beneath the Mountain.

63%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:gameplay, story

63% User Score Based on 98 reviews

Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. If you enjoyed this game, see our list of games similar to Infectious.

69%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

68% User Score Based on 235 reviews

Critic Score 58%Based on 2 reviews

The quiet hamlets of the Vale stand defenseless... No walls, no moats, not even a presentable fence. You'll have to use your resources wisely to transform each village from farm-town to fortress. Build defenses, train troops, and hold the line with powerful heroes in ValeGuard, a Defensive Strategy game. If you enjoyed this game, see our list of games similar to ValeGuard.

38%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

Most mentioned negative aspects:stability, graphics

38% User Score Based on 85 reviews

Vendor Chronicles puts you in the shoes of a Vendor in post-apocalyptia! Manage your trade, set your defences, deal with locals and fight hordes of mutants in this new perspective on post-apocalyptic survival! If you enjoyed this game, see our list of games similar to Desolate Wastes: Vendor Chronicles.

30%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:story, graphics

32% User Score Based on 44 reviews

Test your mind with this twist on a Tower Defense genre, wrapped up in a deep, dark story! Play as a scientist punishing ignorant peasants with burning balls of lava! If you enjoyed this game, see our list of games similar to Fiery Disaster.

53%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:stability, optimization

53% User Score Based on 5,053 reviews

An epic adventure awaits you in Castle Story, a strategy game where you command friendly creatures called Bricktrons. Have them explore, carve, dig and gather resources from vast, spectacular floating islands, reshaping the voxel-based world to your desire! Design and build any structure you can imagine! From mighty and legendary castles to sprawling Bricktron villages. Beware, your Bricktrons w… If you enjoyed this game, see our list of games similar to Castle Story.

30%Game Brain Score

Most mentioned negative aspects:graphics, gameplay

30% User Score Based on 1 reviews

Step into the world of Siege Island, a tribute to the classic arcade game "Rampart" by Atari. Prepare yourself for an immersive 3D action-puzzle game that will test your strategic skills and reflexes. As the Orcish fleet draws near, the duty to safeguard your island from their assaults is yours. If you enjoyed this game, see our list of games similar to Siege Island.

Epic offline war strategy game - build your city, train your army, conquer If you enjoyed this game, see our list of games similar to Parabellum: Siege of Legends.

Kings of Cratia offers an experience that mixes real-time strategy and first-person shooter mechanics. Build your new village and manage your resources efficiently. Watch out for changing weather conditions. Be ready to defend your villages every day when night falls! RTS or FPS, you are free to protect your village the way you want it. You can also command your troops in FPS mode. Every … If you enjoyed this game, see our list of games similar to Kings of Cratia.

58%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

93% User Score Based on 14 reviews

Tower Knight is a deck-building & tower defense strategy game. Make different plans for each challenge's starting deck. Build your deck and adapt your strategy. The map grows as you play your cards. Victory and Defeat Win by surrounding all enemy towers with walls. Your knight can defend themselves, but has limited health. Deck-Building & Tower Defense Build you… If you enjoyed this game, see our list of games similar to Tower Knight.

Spore Valley Spore Valley is a bite-sized resource management puzzle in which you grow an alien slime mold over a hex-based grid while carefully managing a turn-based metabolic resource system. Will you starve and dry out, or will you complete your slime's life cycle, casting off spores into the wind to give rise to the next generation? Your home planet is an arid, sun-blasted planet… If you enjoyed this game, see our list of games similar to Spore Valley.

Discord This land was originally a world full of peace. One day, the devil broke through the boundary. As a soldier, you need to guard the purest and kindest people in the land, so you have to do something. "I am a Viking soldier. I want to protect the entire ethnic group and the purest people in the land!" The young man of that year said similar words, and he was the wisest among hi… If you enjoyed this game, see our list of games similar to ChaosWorld.

Ostracized from society, you join a roman gladiator school to escape justice.       Prepare to entertain the masses by participating in epic arena fights to win your freedom, all the while earning respect, glory and recognition. Up your game by collecting over 200 unique cards and build your deck with authentic roman weaponry and equipment. Explore a secret colony in the southern Mediterranean wit… If you enjoyed this game, see our list of games similar to Blood & Sand: Cards of Salvation.

51%Game Brain Score

Most mentioned positive aspects:music

Most mentioned negative aspects:gameplay

63% User Score Based on 32 reviews

Fight an endless horde of evil minions and survive as long as you can. Collect loot and purchase new upgrades and magic abilities. Summon allies to stand along side you and survive the horde! If you enjoyed this game, see our list of games similar to Tower Survivors.

79%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:stability, grinding

82% User Score Based on 5,587 reviews

Critic Score 69%Based on 2 reviews

"Papers, Please" meets zombie apocalypse. Command the last blockade, inspect survivors, and decide their fate: trust, quarantine, or liquidate. Expand your base, upgrade defenses, and fend off hordes. Every step shapes humanity’s survival. Your choice matters and every mistake costs a life... If you enjoyed this game, see our list of games similar to Quarantine Zone: The Last Check.

Mutant Survivors - Survive the Biological CorruptionAn ancient alien threat. A corrupted world. Your mutation is humanity's last hope. A World Rewritten by Alien EvolutionThree hundred thousand years ago, an alien biotechnological ship crashed into Earth’s polar ice caps. Inside slept Voltris the Luminous Reaper, a Biological Corruption Judge sent to erase civilizations on the brink of collaps… If you enjoyed this game, see our list of games similar to Mutant Survivors.

When the dead rise, only spirits can save us! Description Spiritfall is a strategic tower defense game for the Game Boy Classic where you command an army of mystical spirits to defend against waves of undead invaders! In this supernatural showdown, deploy six unique spirit types across three lanes to stop skeletons, wizards, pumpkin monsters, and floating skulls from reaching your sacred g… If you enjoyed this game, see our list of games similar to Spiritfall.

76%Game Brain Score

Most mentioned positive aspects:gameplay, atmosphere

Most mentioned negative aspects:story, graphics

76% User Score Based on 233 reviews

Survival Machine is a 4 player co-op, 3rd person, survival-adventure game set in vibrant, diverse landscapes. Navigate the ever-changing world aboard the colossal Machine that doubles as your fortress, homestead, and transport. Whether braving the game solo or with friends, explore biomes full of random challenges to gather resources, craft new upgrades, and build structures that will help you sur… If you enjoyed this game, see our list of games similar to Survival Machine.

Genre: Strategy / Tower Defense / Historical Simulation Build, Defend, and Reign Supreme in Feudal Japan!Step into the role of a legendary daimyo in Japanese Castle Strategy Zundamon Castle, a unique blend of tactical warfare, historical simulation, and castle-building strategy. Command your armies, design your perfect fortress, and repel waves of invading forces using traditional Japanese buildi… If you enjoyed this game, see our list of games similar to Voxel Zundamon Castle.