Games like Powerhouse of The Immune System

55%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

55% User Score Based on 102 reviews

Take control of a determined White Blood Cell on a quest for self discovery, vengeance, punishment and annihilation of all evil germs who would dare infiltrate an unsuspecting and innocent human body in this unique and organic experience. Battle evil germs by slamming into them, using your Powerbutt ability to further enhance the damage and pain inflicted. If you enjoyed this game, see our list of games similar to Germ Wars.

61%Game Brain Score

Most mentioned positive aspects:music, story

100% User Score Based on 12 reviews

Listeria Wars is a tactical strategy where we protect the hero’s body from various infections and viruses by controlling the troops of the immune system. We can observe his personal life and even influence it with side effects. If you enjoyed this game, see our list of games similar to Listeria Wars.

The Crafter’s Defense is an action-defense game, combining elements of both tower defense and action games. The player takes on the role of a dungeon core, a human reincarnated as a sentient dungeon, and must defend against waves of invaders. In place of towers, players place traps and dungeon monsters which can be placed directly on the invasion path, where they can attack the invaders, as well a… If you enjoyed this game, see our list of games similar to The Crafter's Defense.

If the game has piqued your interest, please don't hesitate to try the demo. You can also access the demo on Steam. You can take a look at our game's Steam page below and make me very happy by adding FarmTech to your WISHLIST. Thank you for your support Steam  https://store.steampowered.com/app/2361500/FarmTech/ FARMTECH In this world taken over by aliens, you have been given a special mis… If you enjoyed this game, see our list of games similar to FarmTech.

96%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:replayability, stability

96% User Score Based on 108 reviews

Space Raiders in Space is a wave defense roguelike mixing squad management and tower defence mechanics. Command your almost competent crew to loot weapons and supplies, build defenses, and fight their way through the Bugpocalypse. If you enjoyed this game, see our list of games similar to Space Raiders in Space.

75%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, music

75% User Score Based on 478 reviews

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy. If you enjoyed this game, see our list of games similar to Defend Your Life: TD.

51%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, music

56% User Score Based on 43 reviews

Prophour23 is a fast-paced, replayable real-time strategy. It's designed for short, quick plays. A single playthrough will take you about 15 minutes, if you're good. But the next one will be different. And another one as well. If you enjoyed this game, see our list of games similar to Prophour23.

Metacell: Genesis ARCADE is an arcade game inspired by old-school arcade games, with the match 3 mechanic. The basic gist of Arcade mode is a score attack mechanic where you want to survive to level 100 with the highest score. Fight back a never ending spawn of game pieces by making matches of 3 or more before the board fills up, or even worse, you are killed by one of the traps that could spawn a… If you enjoyed this game, see our list of games similar to Metacell: Genesis ARCADE.

What The Fortress!? is surprisingly a tower defense game, but with some twists! You can modify the layout of the map, plan the paths of the incoming enemies, and research dozens of upgrades and towers.Be a real road architectYou have complete control over the map. Carve the path of your enemies, set deadly traps like Ice, Water or Magma tiles. You won't only build towers, but construct the ways be… If you enjoyed this game, see our list of games similar to What The Fortress!?.

Stranded in another solar system on a confusing planet, you must source fuel for your ship. You'll learn how to research, build and defend in increasingly hostile scenarios across the planet. Hive tasks you with mastering three components of colonisation: - Agriculture: providing food to your structures to boost their productivity, - Industry: mining resources and refining them, - Defence: preve… If you enjoyed this game, see our list of games similar to Hive.

Defend the body in vaXinator, a fast-paced action roguelike! As the last white blood cell, unleash powerful abilities and antibodies to fight off waves of infections. Test your reflexes in this microscopic battle for survival. How long can you hold the line? If you enjoyed this game, see our list of games similar to vaXinator.

86%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, grinding

86% User Score Based on 219 reviews

Become the Guardian of the Abyss and lead the Great Migration to bring forth the next Crab God Use your growing knowledge and great power to command your loveable crab babies (Crablings) to restore your ocean domain and protect your successor’s egg as you venture into the watery depths. GROW YOUR CRABLING COLONY Raise your Crablings! Nurture their personalities and potential as they worship you,… If you enjoyed this game, see our list of games similar to Crab God.

94%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, monetization

97% User Score Based on 15,544 reviews

Critic Score 90%Based on 5 reviews

A minimalist game about building and defending a little kingdom. Thronefall is a classic strategy game without unnecessary complexity, just some healthy hack-and-slay. Build up your base during the day, and defend it ‘til your last breath at night. If you enjoyed this game, see our list of games similar to Thronefall.

80%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

88% User Score Based on 9,193 reviews

Critic Score 60%Based on 3 reviews

Kingdom is a 2D side-scrolling strategy/resource management hybrid with a minimalist feel wrapped in a beautiful, modern pixel art aesthetic. If you enjoyed this game, see our list of games similar to Kingdom: Classic.

Escape From The Red Planet is a tower defence game that puts you in the shoes of Commander Abigail Blackwell of The Orion III. After a crash landing that left you stranded on Mars, you must employ serious resource management to keep yourself safe from incoming Martian attacks. While you wait for rescue, keep your solar batteries charged to build up your attack and defence. KEY FEATURES - Three di… If you enjoyed this game, see our list of games similar to Escape From The Red Planet.

74%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:replayability, stability

74% User Score Based on 231 reviews

Risen Kingdom is a real-time strategy game with building and settlement management mechanics. The game is set in a medieval fantasy world years after a great Kingdom has been overrun by hordes of the undead. Now, the bravest warriors are going on a campaign to claim back the land once lost by their ancestors and bring the Kingdom back to its former glory. If you enjoyed this game, see our list of games similar to Risen Kingdom.

87%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

87% User Score Based on 337 reviews

In Castle of Alchemists, a tower defense/top-down action hybrid game with amazing pixel art graphics, play as the Bellator, alchemically enhanced defender, to fight against invaders from other worlds. Delve into the castle, set your traps, equip powerful weapons and gears, and reclaim the castle piece by piece. If you enjoyed this game, see our list of games similar to Castle Of Alchemists.

86%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:stability, grinding

91% User Score Based on 7,467 reviews

Critic Score 81%Based on 11 reviews

BUILD, EXPLORE, DEFEND, CONQUER If you enjoyed this game, see our list of games similar to Kingdom: Classic.

79%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

79% User Score Based on 926 reviews

Dwarfs!?' offers an addictive, fast paced arcade-like experience, with plenty of difficulties and game modes to play around in. As the new overseer for your underground Dwarf base, your job is to manage the small colony and make it as rich as possible, before they meet their inevitable doom! To survive as long as possible, you’ll have to steer and guide your greedy little fellows to the richest p… If you enjoyed this game, see our list of games similar to Dwarfs!?.

97%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, music

97% User Score Based on 226 reviews

Check out the updated version on Steam here! The world is under siege from an unknown enemy. Gates are appearing, spawning demonic entities. Major cities have been destroyed with overwhelming force. Most of the population has been decimated, but the dead rise again to feast on the living. There was no warning, no signs, no dark omen... Just death and destruction. This is the apocalypse. There are… If you enjoyed this game, see our list of games similar to Endgame: Road To Salvation.

Mitosis Mercenary - Cell Wars Jam Game Jam Entry for Trijam #354 You are a white blood cell warrior. Defend the body against an endless onslaught of viruses, bacteria, and other pathogens. Grow stronger through mitosis, collect powerful upgrades, and survive the final wave to achieve victory! Can you grow strong enough to survive the final wave? About the Game Mitosis Mercenary is a top-dow… If you enjoyed this game, see our list of games similar to Mitosis Mercenary.

59%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:graphics

93% User Score Based on 14 reviews

Homeless Life Simulator throws you into the brutal reality of street life. You start with nothing, no home, no money, no safety, and must fight to survive each day. Hunger, debt, and danger are everywhere, but so are the chances to rise again. Every choice matters, and the streets will test your will to endure. From begging, recycling, and stealing to studying, working, and even taking risks in c… If you enjoyed this game, see our list of games similar to Homeless Life Simulator.

69%Game Brain Score

Most mentioned positive aspects:gameplay, music

100% User Score Based on 20 reviews

Can you build and fight through endless levels to bring life and color to your world? Customize towers and troops to ward off enemies in this fast-paced and colorful tower defense. If you enjoyed this game, see our list of games similar to HexeD.

The Road to Gelendzhik Palace - don't let your enemies enter the domain! If you enjoyed this game, see our list of games similar to The Road to Gelendzhik Palace.

52%Game Brain Score

Most mentioned positive aspects:music, optimization

Most mentioned negative aspects:gameplay, replayability

71% User Score Based on 24 reviews

Build, manage and defend your fantasy tavern. If you enjoyed this game, see our list of games similar to TavernHold.

41%Game Brain Score

Most mentioned positive aspects:humor, graphics

Most mentioned negative aspects:gameplay, story

70% User Score Based on 10 reviews

Space Bross is a thrilling blend of action 2.5D roguelite, and Tower Defense genres. You’re a retired astronaut. You had one job: chill. But then they came for your chicken. Now it’s personal. Set off on a chaotic journey across deep space in Space Bross, a roguelite tower defense action game where survival means lasers, loot, and a whole lot of clucking vengeance. Explore dangerous, ev… If you enjoyed this game, see our list of games similar to Space Bross.

70%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

70% User Score Based on 281 reviews

Survival Machine is a 4 player co-op, 3rd person, survival-adventure game set in vibrant, diverse landscapes. Navigate the ever-changing world aboard the colossal Machine that doubles as your fortress, homestead, and transport. Whether braving the game solo or with friends, explore biomes full of random challenges to gather resources, craft new upgrades, and build structures that will help you sur… If you enjoyed this game, see our list of games similar to Survival Machine.

81%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

Most mentioned negative aspects:graphics, story

92% User Score Based on 39 reviews

Become the dungeon master in virtual reality!Take on the role of a powerful demon tasked with building and managing your own underground lair. Unleash your evil genius by designing complex dungeons, summoning a wide range of demonic servants, placing traps, and casting powerful spells to defend your domain against adventurers who dare to enter. Build your own dungeonCommand your imps to dig tunne… If you enjoyed this game, see our list of games similar to Underworld Overseer.

93%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

Most mentioned negative aspects:grinding, story

93% User Score Based on 581 reviews

Protect the oldest tree on Earth from Humanity Tear through hordes of enemies Sow trees to help you Active Tower Defense rogue-like gameplay Personalize your creature with new attacks Huge amount of upgrades Various of starting situation with unique skins A never seen before character with 10/10 procedural animation Play as an invincible mass destruction weapon If you enjoyed this game, see our list of games similar to FROM ASHES, BLOOM.

70%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

70% User Score Based on 166 reviews

Roadmap About the GameKingdom's Deck is a game about survival and growing your kingdom. As the ruler of the land, you must navigate the challenges of staying alive, taking care of your people's requirements, building a powerful army, and protecting your fort from approaching threats Step into the role of the king, entrusted with the fate of an entire realm. Your journey is guided by your co… If you enjoyed this game, see our list of games similar to Kingdom's Deck.

78%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

78% User Score Based on 301 reviews

Black Forest is a single-player, real-time strategy city builder like no other. Where other games focus on expansion and development, Black Forest is all about defending what's yours. Strategically assign villagers, gather resources, reinforce defenses, and above all, maintain the delicate balance until the king's knights arrive. If you enjoyed this game, see our list of games similar to Black Forest.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:optimization, story

91% User Score Based on 1,172 reviews

Thrive is a free, open-source game about the evolution of life. From the lowly tidepools of your home planet, you will rise to cosmic dominance. At every step, powerful creation tools and deep simulation mechanics will aid your species' development. If you enjoyed this game, see our list of games similar to Thrive.

71%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:stability, story

71% User Score Based on 410 reviews

This Goblin Tribe Simulator brings a challenging blend of chaos and creativity to the city-building genre. Build dwellings, manage your resources, defend your goblins, and grow your tribe to face other races and even the Gods! Do you have what it takes to control the chaos and rule the unruly? If you enjoyed this game, see our list of games similar to Goblins of Elderstone.

75%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

75% User Score Based on 606 reviews

Your community was taken down by a heavy storm which caused an apocalypse and unleashed the living dead. Together with the other survivors, it is your task to rebuild and to allow that sustainable life can still be assured. Cultivate your farm and manage your restaurant to provide food and deal with all the zombies. It’s a strange Time Management Game. The lightheartedness of a casual game collid… If you enjoyed this game, see our list of games similar to Farm for your Life.

61%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, optimization

61% User Score Based on 190 reviews

‘Alien Marauder’ is a real-time strategy game with survival and confrontation theme.In this game, you will be the leader to a treacherous alien planet, get all kinds of supplies to build your outpost, and deploy troops to resist the incoming vexans strategically! If you enjoyed this game, see our list of games similar to Alien Marauder.

83%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

86% User Score Based on 7,734 reviews

Critic Score 78%Based on 5 reviews

Mystery to discover, darkness to conquer. A noio and Raw Fury game. If you enjoyed this game, see our list of games similar to Kingdom: New Lands.

80%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:replayability, grinding

80% User Score Based on 523 reviews

Join the wonderful and amazing world of microorganisms. If you enjoyed this game, see our list of games similar to Microcosmum: survival of cells.

87%Game Brain Score

Most mentioned positive aspects:gameplay

Most mentioned negative aspects:graphics, optimization

87% User Score Based on 54 reviews

DISCLAIMER: Hey there! Welcome to the first version of 'Towers Together' - we're so excited to have you here! We want to be upfront with you - this version may have some bugs and balance issues, but don't worry, we're working on improving the game every day. We'd love to hear from you too! If you run into any issues or have any feedback to share, join our social medias and help us create the best … If you enjoyed this game, see our list of games similar to Towers Together: Beginnings.

73%Game Brain Score

Most mentioned positive aspects:graphics, music

Most mentioned negative aspects:gameplay

73% User Score Based on 51 reviews

Plant your strategy! Defend mystical trees in this captivating strategy game If you enjoyed this game, see our list of games similar to Nanuleu.

69%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

69% User Score Based on 127 reviews

An action-farming-roguelite, full of whimsical flora and mischievous creatures that really want to ruin your dark and mysterious plans of… Going vegan! If you enjoyed this game, see our list of games similar to Voltaire The Vegan Vampire.

59%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:stability, grinding

53% User Score Based on 385 reviews

Critic Score 66%Based on 7 reviews

Machiavillain is an evil mansion management and strategy game, inspired by Dungeon Keeper, Prison Architect and all the horror movie clichés! Build your own manor, raise your monsters, set up your traps, and exterminate your victims. But to gain reputation you'll have to slay by the horror movie rules! If you enjoyed this game, see our list of games similar to MachiaVillain.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story

91% User Score Based on 70 reviews

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time! If you enjoyed this game, see our list of games similar to Life on the Edge.

94%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:stability, optimization

94% User Score Based on 1,203 reviews

What is Vectorio Classic?Vectorio Classic is a simple survival base-building game where the objective is to claim resources you find around the map and use them to research new powerful weapons and technology. Use your new tech to survive, expand, and defeat all four guardians and put an end to the onslaught of enemy shapes! There's more to your base then just the defensive side though. You'll n… If you enjoyed this game, see our list of games similar to Vectorio Classic.

83%Game Brain Score

Most mentioned positive aspects:gameplay, optimization

Most mentioned negative aspects:graphics, stability

83% User Score Based on 263 reviews

Castle Craft is a game where players can build huge castles in an ancient wartorn world and must defend them against hordes of enemies in siege battles of epic proportions. Castle Craft is a unique blend of the voxel sandbox genre, action, and tower defense. If you enjoyed this game, see our list of games similar to Castle Craft.

76%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, story

83% User Score Based on 590 reviews

Critic Score 40%Based on 1 reviews

Over 9000 Zombies! is top-down arcade action blown out of all reasonable proportions. An endless horde of zombies is coming your way, how long can you survive? If you enjoyed this game, see our list of games similar to Over 9000 Zombies!.

66%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:optimization, stability

66% User Score Based on 293 reviews

Beneath the Mountain is a dwarven city-builder and real-time-strategy game. Mine your way into the mountain, discover gold and silver, construct buildings, recruit an army, build traps, and defeat the vile creatures that lurk in the dark caves of the mountain. Most importantly, find the heart of the mountain before the orcs destroy your kingdom. Beneath the Mountain is a top-down, isometric, 3D … If you enjoyed this game, see our list of games similar to Beneath the Mountain.

93%Game Brain Score

Most mentioned positive aspects:graphics, replayability

Most mentioned negative aspects:gameplay, story

93% User Score Based on 337 reviews

★ Attack on Toys: LOCAL & ONLINE SPLIT-SCREEN - 2025 UPDATE! NOW AVAILABLE!★ Remembering playing Split Screen with family or goes to friend house and bringing your own controller & memory card? You could do exactly that with Attack on Toys! Fully Dynamic Offline / Online Split Screen and Multi Profile - Save Data Memory System! Please see below for more details & features about the S… If you enjoyed this game, see our list of games similar to Attack on Toys.

63%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:gameplay, story

63% User Score Based on 98 reviews

Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. If you enjoyed this game, see our list of games similar to Infectious.

69%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

68% User Score Based on 235 reviews

Critic Score 73%Based on 2 reviews

The quiet hamlets of the Vale stand defenseless... No walls, no moats, not even a presentable fence. You'll have to use your resources wisely to transform each village from farm-town to fortress. Build defenses, train troops, and hold the line with powerful heroes in ValeGuard, a Defensive Strategy game. If you enjoyed this game, see our list of games similar to ValeGuard.

86%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, stability

86% User Score Based on 579 reviews

Protolife is an unique tower-based strategy game which gives you a direct control over the builder robot in a struggle against the hungry proto-life organism. If you enjoyed this game, see our list of games similar to Protolife.