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Games like Genome Guardian: Prologue

Games like Genome Guardian: Prologue

Games like Genome Guardian: Prologue

Looking for games like Genome Guardian: Prologue? Here are top survival role playing shooter recommendations with a horror and science fiction focus, selected from player-similarity data — start with Genome Guardian, X Invader or Cell Command.

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  1. 92%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, grinding
    92% User Score Based on 684 reviews

    Dive into a microscopic alien world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive 8 game modes, each with multiple ascension levels ("depths"). Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to dis… If you enjoyed this game, see our list of games similar to Genome Guardian.

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    86%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, stability
    86% User Score Based on 182 reviews

    Become a master hacker 'X' and hack into the digital world of a corrupt conglomerate. Use a variety of weapons and hacking add-ons to create your own combat build and wipe out disturbing enemies. Please enjoy the hack and slash action! If you enjoyed this game, see our list of games similar to X Invader.

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  3. 98%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:story, graphics
    98% User Score Based on 144 reviews

    A turn-based roguelite unlike anything you've played beforeDive into the microscopic world - cure the virus ravaging the planet. In Cell Command, units grow when they move, and attacks shrink them. A "tank" could be a long, winding python that clogs up the battlefield & encircles its prey!     Mix DNA nucleotides A C G T to discover unique, unicellular combatantsCommand c… If you enjoyed this game, see our list of games similar to Cell Command.

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  4. 80%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:monetization, graphics
    97% User Score Based on 33 reviews

    Tears of Vanfell - Chapter 1 is an action-packed dungeon crawler with roguelike and hack-'n-slash elements. Choose between a wide cast of characters and climb the Mountain as you swap weapons and grow stronger as a team of up to four player in online Co-op. Explore and climb the procedurally-generated Mountain to find and defeat Bosses, and continue on your journey. During your adventure, you'… If you enjoyed this game, see our list of games similar to Legacy: Tears of Vanfell - Chapter 1.

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  5. 47%Game Brain Score
    Most mentioned positive aspects:graphics
    Most mentioned negative aspects:monetization, music
    64% User Score Based on 25 reviews

    WARNING: This is a demo version of Hell Survivors, make sure to check out the main game page! Face an onslaught of demonic hordes and survive through inferno in Hell Survivors. Create powerful builds from a variety of heroes, weapons, and special abilities in order to survive for 20 minutes. Are you strong enough to come back from purgatory, or will you allow the nightmare creatures to consume… If you enjoyed this game, see our list of games similar to Hell Survivors: Prologue.

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  6. 95%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:story, grinding
    95% User Score Based on 1,107 reviews

    Utopia Must Fall is a vector-flavored base-defending arcade shooter with rapid progression, procedurally generated attack waves and enough upgrade variety to suit both the defensive or aggressive player.It incorporates elements from tower defense, roguelites and beyond, all neatly packaged into a laser-sharp bullet-purgatory arcade frenzy! Features Easy To Learn: firing happens automatically, just… If you enjoyed this game, see our list of games similar to Utopia Must Fall.

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  7. 60%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:monetization, graphics
    89% User Score Based on 18 reviews

    Get the full game About the Game This prologue features the beginnings of Blacken Slash – a tactical RPG fusing the best of roguelikes, turn-based tactics and hack and slash games – made by a solo developer with a penchant for minimalist designs. Fight through bite-sized tactical puzzles Create powerful builds from a plethora of items which grant you skills and can change gameplay mechanic… If you enjoyed this game, see our list of games similar to Blacken Slash: Prologue.

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  8. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding
    95% User Score Based on 1,455 reviews

    Astro Prospector is an incremental bullet heaven about mining cofferoids and fighting SpaceCorp. Collect resources, upgrade your ship and become unstoppable. Return AstroCoffee to humanity! If you enjoyed this game, see our list of games similar to Astro Prospector.

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  9. 94%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    97% User Score Based on 10,045 reviews
    Critic Score 80%Based on 1 reviews

    Nova Drift distills the mechanical depth of an action RPG into classic arcade space combat. Control an endlessly evolving bio-mechanical ship, face legions of strange and deadly foes, and ride the wake of a dying star across the void. If you enjoyed this game, see our list of games similar to Nova Drift.

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  10. 95%Game Brain Score
    Most mentioned positive aspects:humor, emotional
    Most mentioned negative aspects:monetization, gameplay
    95% User Score Based on 59 reviews

    Synopsis Your ducks have worked tirelessly to amass a fortune in gold and diamonds, but their hard-earned treasure has caught the eye of a ruthless chicken gang. These feathered fiends are on a mission to plunder your wealth and decimate your duck army. With addictive gameplay, endless challenges, and a touch of feathered fun, Quacker Bros offers hours of entertainment for strategy enthusiasts a… If you enjoyed this game, see our list of games similar to Quacker Bros : First Heist.

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  11. 76%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization
    85% User Score Based on 40 reviews

    Prologue and the official version of the difference between Levels: one in the prologue, four in the official version Follow-up Program: The game will continue to update content after release, which includes: More bosses: different fighting styles and types of boss fights. More tech: weird and wacky tech combinations. More weapons: more basic weapons and weapon variants. More game modes: In additi… If you enjoyed this game, see our list of games similar to Godrop:Prologue.

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  12. 97%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:optimization, story
    97% User Score Based on 354 reviews

    Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian. Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves! Make stationary turrets, psychic water sprinkler motorbikes, or maybe … If you enjoyed this game, see our list of games similar to Genome Guardian 2.

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    90%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, monetization
    90% User Score Based on 1,080 reviews

    Gear up for a battle through hell in this roguelite Bullet Heaven Arena Autoshooter with Doom-inspired gore vibes, metal music, and a satisfying combat feel. Wield five weapons at once, upgrade and merge them to forge indestructible builds, and bring divine justice to a world on the brink of chaos. If you enjoyed this game, see our list of games similar to Arms of God.

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  14. View Game
    97%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:stability, grinding
    97% User Score Based on 2,360 reviews

    Emberward is a unique tower defense game that focuses on maze building and interesting tower mechanics. Construct mazes with blocks of different shapes and set up defense towers on them to withstand the onslaught of monsters! If you enjoyed this game, see our list of games similar to Emberward.

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  15. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, story
    85% User Score Based on 182 reviews

    Against Great Darkness Prologue is a brick-breaker, bullet hell, roguelite. Choose your pagan deity and break free from the clutches of Lucifer. Juggle your disks to defeat your enemies as you progress through the waves of minions and confront relentless demonic bosses. In each run, acquire powerful relics that will assist you in your escape. Juggle the disks to unleash the power they hold and … If you enjoyed this game, see our list of games similar to Against Great Darkness.

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  17. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, story
    91% User Score Based on 454 reviews
    Critic Score 84%Based on 2 reviews

    Blast hordes of alien ships into junk. Collect the scrap to upgrade your ship into an unstoppable force of destruction. Unlock new characters and weapons and upgrade your stats between runs. If you enjoyed this game, see our list of games similar to Void Scrappers.

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  19. 62%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization, story
    90% User Score Based on 20 reviews

    Dive into a world of surprises, where every card flip could be your ticket to victory or trouble. The prologue showcases a part of the mysterious forest that changes with every game. Can you master the art of strategic card flipping and uncover the first plot mysteries? Get a taste of a larger adventure that combines tactical thinking, luck, and exploration in this captivating roguelike experienc… If you enjoyed this game, see our list of games similar to Forest Dump: Prologue.

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  21. 54%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization, story
    86% User Score Based on 14 reviews

    Take up the role of the Hell Governor and embrace the challenge of welcoming souls who perished in major, historically real human disaster. Build your city, manage your resources while defending the chaos from demons who steal and kill your folks....and also that GIANT TITAN lurking around. If you enjoyed this game, see our list of games similar to The HELL Prologue.

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  22. View Game
    81%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:monetization, story
    95% User Score Based on 37 reviews

    Enter a world of colorful wacky characters. You the player are an entity that has entered their world and control the main character without her knowledge. As you progress she will slowly start to realize the decisions she's making aren't her own. It's possible you can be of aid or you can choose to be an enemy. Your presence has caught the attention of something sinister and it's up to you to dec… If you enjoyed this game, see our list of games similar to Home.

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  23. 98%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, story
    98% User Score Based on 274 reviews

    A fast-paced paint 'em up roguelike where each level you beat becomes a masterpiece to add to your colorful collection. If you enjoyed this game, see our list of games similar to Antipaint.

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  24. 52%Game Brain Score
    Most mentioned positive aspects:atmosphere
    Most mentioned negative aspects:monetization, gameplay
    78% User Score Based on 18 reviews

    Monster Showdown: Prologue includes the first 3 out of 10 maps of this action packed VR Shooter. WEAPONS: Buy your favorite weapons from a choice of over 60 from a dispenser at the wall or try your luck at the enigmatic box for a chance to get a really powerful gun. You can also attack enemies with melee weapons by swinging your VR controller. The more skillful your swings are the more damage you… If you enjoyed this game, see our list of games similar to Monster Showdown: Prologue.

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  25. 86%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding, stability
    86% User Score Based on 579 reviews

    Protolife is an unique tower-based strategy game which gives you a direct control over the builder robot in a struggle against the hungry proto-life organism. If you enjoyed this game, see our list of games similar to Protolife.

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  26. 94%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, stability
    96% User Score Based on 6,430 reviews
    Critic Score 80%Based on 1 reviews

    A tower defense game where you have to defend Power Cores from being stolen. Tower construction is limited to specified platforms on where you can place 1 out of 10 diffrent upgradeable towers. Towers can not be destroyed by the enemies. Tower placement is key to progress in this game as they each have pros and cons. During the game you battle a variety of 15 diffrent "Insectoid" enemies with vari… If you enjoyed this game, see our list of games similar to Defense Grid: The Awakening.

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  27. 92%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, optimization
    92% User Score Based on 847 reviews

    Rocket Rats is a survivors-like game where you defeat cheese-based astral bodies in space – as a rat! Clear waves of enemies, collect cheese, upgrade your gear, and conquer the moon! If you enjoyed this game, see our list of games similar to Rocket Rats.

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  28. 87%Game Brain Score
    Most mentioned positive aspects:music, graphics
    Most mentioned negative aspects:monetization
    87% User Score Based on 60 reviews

    CONCEIT: Neongarten is a minimalist cyberpunk citybuilder where you build from the ground up! Find synergies between buildings to maximize their taxes, pit mega-corps against idealistic hackers, and place toxic waste dumps on top of coffee shops. Chill out to lo-fi tunes while you grow your city block one cube at a time. This full game has been released! More buildings, new factions, Creative mo… If you enjoyed this game, see our list of games similar to Neongarten.

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  29. 83%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:story, grinding
    83% User Score Based on 861 reviews

    Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core! When the aliens swarm your maze and everything seems lost, use active abilities like Air Strike and Freeze to tilt the battlefield to your advantage. If you enjoyed this game, see our list of games similar to Super Sanctum TD.

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  30. 94%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, monetization
    94% User Score Based on 4,682 reviews

    The Horde is coming, but you're ready to fight it! Arm your team to your liking and discover which synergies work best against thousands of the undead. Survive, evolve, and break the limits in this casual yet heart-pumping rogue-lite reverse bullet hell. If you enjoyed this game, see our list of games similar to Yet Another Zombie Survivors.

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  31. 97%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization, replayability
    97% User Score Based on 109 reviews

    Galactic Glitch is a space-roguelike with fast and physical combat. You fight in bubbles of glitched spacetime, hurling rocks, bouncing foes off walls and destroying your multi-part enemies piece-by-piece in tough-but-fair, souls-inspired combat. Explore, destroy, die, repeat. If you enjoyed this game, see our list of games similar to Galactic Glitch.

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  32. 72%Game Brain Score
    Most mentioned positive aspects:atmosphere, humor
    Most mentioned negative aspects:gameplay, story
    77% User Score Based on 44 reviews

    Enter the core of craftsmanship with Medieval Crafter: Blacksmith Prologue. Discover the intriguing realm of a blacksmith, extract precious ores, create legendary weapons, and master forging in a vibrant fantasy world! If you enjoyed this game, see our list of games similar to Medieval Crafter: Blacksmith Prologue.

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  33. View Game
    96%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, optimization
    96% User Score Based on 1,303 reviews

    Gnomes is a turn-based tower defense with deep roguelike progression, set in ever-expanding, procedurally generated biomes. Build, farm and defend your village as you push deeper into goblin-infested territory. Unlock powerful upgrades and craft your environment to survive the endless goblin horde If you enjoyed this game, see our list of games similar to Gnomes.

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  34. 97%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, stability
    97% User Score Based on 1,378 reviews

    From Glory To Goo is a Sci-Fi Survival RTS set on an alien world. Serve as humanity's bulwark by establishing a colony and supporting your colonists still in orbit. But beware, for The Goo, a relentless and shape-shifting force approaches from all sides, even above and below. Expand Your ColonyExpand your colony in a hostile alien environment and ensure you can supply enough shelter, water and pow… If you enjoyed this game, see our list of games similar to From Glory To Goo.

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  35. 94%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, monetization
    97% User Score Based on 15,544 reviews
    Critic Score 90%Based on 5 reviews

    A minimalist game about building and defending a little kingdom. Thronefall is a classic strategy game without unnecessary complexity, just some healthy hack-and-slay. Build up your base during the day, and defend it ‘til your last breath at night. If you enjoyed this game, see our list of games similar to Thronefall.

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  36. 89%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:monetization, optimization
    89% User Score Based on 70 reviews

    Play Abathor Atlantis Landing and relive the glory of arcades in this action platformer for up to 4 players. If you enjoyed this game, see our list of games similar to Abathor: Atlantis Landing.

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  37. 83%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, stability
    85% User Score Based on 1,092 reviews
    Critic Score 75%Based on 1 reviews

    Let Them Come is a fast paced pixel art shoot ‘em up. Twitchy trigger fingers and focused battle tactics are the order of the day as wave after wave of alien-like creatures try to take you down. If you enjoyed this game, see our list of games similar to Let Them Come.

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  38. 90%Game Brain Score
    Most mentioned positive aspects:story, graphics
    Most mentioned negative aspects:stability, grinding
    93% User Score Based on 1,918 reviews
    Critic Score 80%Based on 3 reviews

    X-Morph: Defense Complete Edition includes: X-Morph: Defense core game, European Assault DLC, Survival Of The Fittest DLC, Last Bastion DLC If you enjoyed this game, see our list of games similar to X-Morph: Defense.

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  39. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    85% User Score Based on 990 reviews

    Planets are falling. Build something that can take them back. A swarm of AI bots is tearing across the galaxy, assimilating everything in its path. As a maverick Tech jockey with nerves of steel, it's on you to clean up the carnage. Build something fast enough, mean enough or heavy enough to push back, then smash it all into scrap. TerraTech Legion is a bullet heaven from Payload Studios, the te… If you enjoyed this game, see our list of games similar to TerraTech Legion.

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  40. 96%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, stability
    96% User Score Based on 1,665 reviews

    You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions. If you enjoyed this game, see our list of games similar to Pathogenic.

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  41. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:optimization, grinding
    98% User Score Based on 2,233 reviews
    Critic Score 89%Based on 5 reviews

    Defend the Earth from an alien invasion in the ULTIMATE fusion of deckbuilding and grid-based tactics. Pilot a mech, discover game-breaking combos, and protect the future of humanity in this endlessly replayable roguelike. If you enjoyed this game, see our list of games similar to StarVaders.

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  42. 57%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, optimization
    57% User Score Based on 97 reviews

    Astro Looter is an combination of roguelike, survival and tower defense with mining element. Follow armored heroes like the domineering Storm Striker, Air Colonel, or Trauma Specialist across various planets to plunder regional minerals. Utilize weapons, orbital bombardments, airdropped defense towers, and lucky airdrops to eliminate the ever-emerging alien bugs and retreat successfully. Upgrade y… If you enjoyed this game, see our list of games similar to Astro Looter.

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  43. 80%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization, grinding
    80% User Score Based on 54 reviews

    Chapter 0 for Time Survivors, the Most Historically Inaccurate Roguelike ever. Slay hordes of minions as Lincoln, Tesla, Cleopatra and other historic heroes with new unique abilities! Collect resources, unlock and enhance gameplay through our tree-based metaprogression. Forge your own epic journey If you enjoyed this game, see our list of games similar to Time Survivors: Chapter 0.

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  44. 50%Game Brain Score
    Most mentioned positive aspects:graphics, music
    Most mentioned negative aspects:monetization, gameplay
    68% User Score Based on 25 reviews

    A first-person horror maze game. Hiding & Standing still is Death. Run or you are DEAD. Trapped in a realm of nightmarish mazes with your only hope of survival is to find all of the pages to the mysterious book and ESCAPE! This is the first chapter in The Paper Trials. survive the first maze. You are not alone. The doctors in there and they are looking for you. Will you survive? … If you enjoyed this game, see our list of games similar to The Paper Trials.

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  45. 82%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:monetization, music
    82% User Score Based on 76 reviews

    Nadir is a roguelike deck-builder with a twist: the cost to play a card is an enemy reaction you can predict. Craft your own cards to slay powerful demons. Gather resources, expand your city, grow in power and conquer the underworld. If you enjoyed this game, see our list of games similar to Nadir: A Grimdark Deckbuilder.

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  46. 69%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:optimization, story
    69% User Score Based on 646 reviews

    The last ship against the endless. Exterminate as many as you can, and gather points to upgrade your ship from a crafted deck of equipment and power-ups. Will your choices be enough to overcome the thousands hunting you? Survive the swarm in this rogue-lite + survivors + asteroids mashup. If you enjoyed this game, see our list of games similar to Star Survivor.

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  47. 97%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:story, grinding
    97% User Score Based on 296 reviews

    Beat Invaders is a cool space Shoot-Em-Up. Blast your way through enemy fleets! Upgrade your ship with rockets & armor! Defeat the final boss! All to flashy neon musically charged visuals! If you enjoyed this game, see our list of games similar to Beat Invaders.

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  48. 97%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, story
    97% User Score Based on 4,316 reviews

    Amass an army of deamonic undead to fight endless waves of heroes intent to end your boneraising ways! In this gothic-horror auto-battle roguelite, use the bones of slain heroes to raise your minions, collect powerful relics and spells, and unlock meta upgrades, all to survive King Gigald's crusade! If you enjoyed this game, see our list of games similar to Boneraiser Minions.

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  49. 96%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, optimization
    96% User Score Based on 2,422 reviews

    Defender’s Quest is a tower defense and RPG hybrid that features classic tower defense gameplay intermingled with RPG mechanics. Recruit your troops and pick the ones that best fit your needs as you’ll have a wide variety to choose from: berserkers, archers, healers, mages, and many more. Upgrade their skills, items, and abilities and watch your party grow in power. If you enjoyed this game, see our list of games similar to Defender's Quest: Valley of the Forgotten.

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  50. 89%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:stability, story
    89% User Score Based on 125 reviews

    WELCOME TO PROLOGUE OF NONE SHALL INTRUDE!In this free version, you are able to conquer the first Act of Herelon. Will you be able to defeat the Dragon Slayer and secure the first part of the map? None Shall Intrude invites you to embrace the unparalleled power of a Raid Boss in a unique and immersive gaming experience. Prepare to traverse vibrant realms, engage in intense battles, and conquer … If you enjoyed this game, see our list of games similar to None Shall Intrude: Descent.

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