Games like Immune System Tower Defense

Send out your white blood cells to fight bacteria, viruses, parasites and cancer! A biologically accurate tower defense game about the immune system. If you enjoyed this game, see our list of games similar to Immune System Tower Defense.

91%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story

91% User Score Based on 70 reviews

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time! If you enjoyed this game, see our list of games similar to Life on the Edge.

Command your virus to invade cells, wage an all-out war against the immune system, and conquer the world. Cell Battlefield Cells are the primary battlegrounds of the game. You need to command your virus to enter host cells and utilize the replication mechanisms within the cell nucleus to rapidly reproduce. As the virus multiplies, the host cell's apoptosis signaling pathway will gradually be act… If you enjoyed this game, see our list of games similar to Propa..

55%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

87% User Score Based on 15 reviews

Gelluloid Domination is a fast-paced strategy game of fantasy biology. Start with a single fragile cell and expand across the network, assimilating rivals to grow your gel-powered army. Evolve mutations, unlock new abilities, and outmaneuver deadly pathogens. Adapt and conquer, expand or be consumed. Every decision shapes the network — will you achieve total domination? If you enjoyed this game, see our list of games similar to Gelluloid Domination.

75%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, music

75% User Score Based on 478 reviews

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy. If you enjoyed this game, see our list of games similar to Defend Your Life: TD.

Deep within a living biological organism, you are the last surviving cell of the system. Fight against corruption! The Last One Bullet is a real-time tower defense game with roguelite elements, combining minimalist aesthetics with deep strategic gameplay. ——— THINK, BUILD, SURVIVE ——— Starting from the Cellular Nexus, the core of your system, construct towers with a wide variety of unique p… If you enjoyed this game, see our list of games similar to thelastonebullet.

Just as the COVID-19 pandemic is starting to sweep through the world, Antidote Laboratories receives a strange package. You are assigned to study it and WHAM!, get thrown into the frontlines of medical science. Based on real events and loaded with useful facts about COVID-19, the Antidote COVID-19 takes you on a science adventure! • Defend the stem cell against viruses and bacteria • Build your o… If you enjoyed this game, see our list of games similar to Antidote COVID-19.

61%Game Brain Score

Most mentioned positive aspects:music, story

100% User Score Based on 12 reviews

Listeria Wars is a tactical strategy where we protect the hero’s body from various infections and viruses by controlling the troops of the immune system. We can observe his personal life and even influence it with side effects. If you enjoyed this game, see our list of games similar to Listeria Wars.

Cellula is a cell biology simulator disguised as a strategy game. Manage a colony of living cells. Build membranes from individual phospholipid bricks, place organelles, import nutrients, fight viruses, detect cancer, and divide your cells to grow. No tutorials. No lectures. Learn real biology by keeping your cells alive. WHAT YOU'LL DOStart with a single cell: a ring of phospholipid bricks tha… If you enjoyed this game, see our list of games similar to Cellula.

Leukocyte is an action-adventure game set inside the human body. You are a white blood cell and part of the immune system. Your mission is to protect the body from viruses, bacteria, and other dangerous threats. Explore different areas of the body, complete objectives, rescue allies, gather resources, and evolve your abilities through DNA mutations. Mutations can change the way you play and help… If you enjoyed this game, see our list of games similar to Leukocyte.

In A Hero and His Body, you take on the role of the immune system’s commander, leading a team of heroic immune cells against invading bacteria and viruses. Dive deep into the human body, fight intense turn-based battles, and protect vital organs from dangerous infections! This colorful and engaging strategy game is designed to be both fun and educational, teaching players about the immune system … If you enjoyed this game, see our list of games similar to A Hero And His Body.

Welcome to the Human Immunity Command Center~ As a new commander, you must command cells to attack, defeat invading bacteria and viruses, and defend body cells. Be careful! Some immune cells could be too powerful to kill everything, including our original cells! Here, you can produce different immune cells, deploy your resistant cell line of defense, learn how bacteria and viruses damage human cel… If you enjoyed this game, see our list of games similar to 战地细胞（Battlefield Cell）.

49%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, music

48% User Score Based on 336 reviews

Critic Score 50%Based on 2 reviews

Oil Rush is a naval strategy game that takes place in a world where nuclear war has melted the ice caps, changing the face of the planet forever. Oil Rush offers unique gameplay, avoiding micromanagement of every single unit, while still providing full control over all important aspects of strategy and economy. If you enjoyed this game, see our list of games similar to Oil Rush.

73%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, stability

73% User Score Based on 266 reviews

Critic Score 75%Based on 1 reviews

Revolutionary Tower DefenseDANGER! Earth is under attack from a vast armada of flying saucers. Only you can stop the invasion of these relentless alien monsters - don't let a single one through! Get ready for a revolution in tower defense that will send you spinning. Defend the solar system by sending satellites into orbit around planets, moons and space stations. Create the perfect defense by rot… If you enjoyed this game, see our list of games similar to Unstoppable Gorg.

87%Game Brain Score

Most mentioned positive aspects:story, graphics

Most mentioned negative aspects:gameplay

91% User Score Based on 46 reviews

Command cryptocurrencies to fight against blockchain threats in this stylish, high-action tower defense game. Prices influence the powers of your cryptos in real time. Features squad customization, skill trees, base building, mini-games, and Endless mode. Tip: Keep calm and "HODL" the line. If you enjoyed this game, see our list of games similar to Crypto Against All Odds.

Alien Bloom is a three-player turn-based strategy card game in which rival factions compete for control of Earth. Players expand across a world map, attack territories, resolve battles using card-game mechanics, deploy spaceships, and pursue multiple victory conditions. If you enjoyed this game, see our list of games similar to Alien Bloom.

Tired of “target dummy” enemies that just line up to die? Try Germ Swarm — pathogens mutate, coordinate, and fight back! In Germ Swarm, you command the human immune system from a microscopic perspective, battling waves of bacteria, viruses, and other pathogens as infection spreads throughout the host. ⚠️ Contains large numbers of bacteria, viruses, and microscopic biological imagery that may be … If you enjoyed this game, see our list of games similar to Germ Swarm: Evolution & Mutation.

Automate highly unstable and unreliable robots using microprograms installed along their paths. Design an automated system that is prepared to handle the challenges of a super weird environment, full of automated hazards left here long before your arrival. If you enjoyed this game, see our list of games similar to SuperWeird.

Immune Defense Control the body’s last line of defense in this microscopic tower defense game! About the Game Immune Defense is a colorful 2D tower defense game where you play as the body’s immune system, protecting it from waves of invading bacteria, viruses and parasites. You’ll place powerful immune cells like macrophages, neutrophils, and T-cells along the bloodstream to stop infections fr… If you enjoyed this game, see our list of games similar to ImmuneDefense.

Immune Rush Game! Get ready for Immune Rush, a fast-paced, action-packed top-down shooter set inside the human body! You’ll step into the shoes of a brave white blood cell, battling waves of nasty invaders like viruses, bacteria, and parasites. Core Features: ⚡ Non-Stop Action: Shoot enemies and level up your skills to become the ultimate immune defender! Adorable Doodle Art Style: The g… If you enjoyed this game, see our list of games similar to Immune Rush.

This is a game made for RPG Maker web 'No Travel' Game JamThe whole game was developped from march 29 to april 27 2020. See things from the other side by playing as a virus. Try to lead a successful infection without hindering too much your Host health.  Play as the virusQuantity of virus in Host blood is call Viral Load. As you infect more cells, your Viral Load will increase. But when the Host … If you enjoyed this game, see our list of games similar to Life of a virus.

Fly your Microbot through the bloodstream, into the connective tissue and then launch a nanobot and fly it around the surface of a white blood cell.  Plays on Windows machines.  (Not Surface, Mac or Linux.)  We are working on a new games...  follow Molecular Jig Games for updates!! ----- Immune Attack was designed, developed and evaluated for learning outcomes by the Learning Technologies Program… If you enjoyed this game, see our list of games similar to Immune Attack.

"Inoculation: Defend the Body" is an immersive tower defense game set within the intricate landscape of the human body. Players embark on a crucial mission to protect the body from relentless waves of invading pathogens seeking to cause chaos and illness. The game unfolds within the intricately designed environments representing vital organs, bloodstream passages, and cellular structures. Each … If you enjoyed this game, see our list of games similar to Inoculation.

Protect your organs (the source of life) with the versatile white blood cells as an invasion of bacteria try and attack the body. Be careful, a life is in your hands. Build towers, walls, and traps to fight back against the bacteria. Tutorial in game.Made in 7 days for Major Jam 6: Life. If you enjoyed this game, see our list of games similar to Powerhouse of The Immune System.

Fight the virus in this fast paced arcade shooter with a dash of tower defense! If you enjoyed this game, see our list of games similar to Super Virus Defense.

Nanocell Squad is an Real-time Adventure Strategy (RTAS) game where you control a group of nanobot-infused immune cells on your quest to defeat the evil and mysterious P.A.I.N and become a hero in a world that sees you as a villain. Tactics are the focus, it’s up to you to choose What units will you build? Each unit has its own strengths and weaknessesExplore to find upgrades and allies or focus o… If you enjoyed this game, see our list of games similar to Nanocell Squad.

Remission Possible is an educational 3D rail shooter about fighting cancer with microbubbles!  Steer your ship down winding blood vessels, collect bubbles of life-saving medicine, then use your ship's ultrasound to pop them and deliver their medicine wherever it's needed! Complete missions and pass your training quizzes to unlock new abilities for your ship to give you better control over the mic… If you enjoyed this game, see our list of games similar to Remission Possible.

Blood Sells is an early game prototype created over 3 days in my own personal Game Jam.The player takes on the role of the immune system of someones body, fighting against diseases and bacteria in order to keep unhealthy blood from entering the heart.The game gets progressively harder the longer you play it, starting with a slow blood rate, as if the host had only just woken up, and steadily incre… If you enjoyed this game, see our list of games similar to Blood Sells.

BackgroundOn a midnight in your thirties, you wake up surrounded by Lesser Demons closing in for the kill. Soaked in cold sweat. The mountains around you make no sense; the city walls pulse like a living heart. Your mind goes blank— This doesn't look anything like your world. You are Ren Xia. A medical doctor. A surgeon. And the vast continent before you is called Xiaoyao—a land worshipped b… If you enjoyed this game, see our list of games similar to 大侠博士.

96%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding, stability

96% User Score Based on 1,665 reviews

CELULLAR COMBAT EVOLVED In Pathogenic, you are the disease. Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and conquer your human host. To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell… If you enjoyed this game, see our list of games similar to Pathogenic.

An infection has struck the body! As the mighty T-Cell, it's your duty to eradicate the invading pathogens! Consume pathogens to earn mito energy, and use it to purchase upgrades and summon allies in your battle to protect the body. If all your body cells die, it's game over for you. Utilising squishy softbody physics and hand-drawn graphics, this game will take you on a journey through the body… If you enjoyed this game, see our list of games similar to Going Viral.

66%Game Brain Score

Most mentioned negative aspects:gameplay, grinding

81% User Score Based on 32 reviews

What if MOBAs and RTS games had a baby? Rover Wars combines resource management, farming, building and strategy into an intense tug of war. Fight in an interplanetary campaign and challenge your friends in the configurable Battle Mode. If you enjoyed this game, see our list of games similar to Rover Wars.

68%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, music

77% User Score Based on 39 reviews

Welcome to the dangerous micro world hidden inside the human body. Pilot a ship through the bloodstream. Mine resources, fight microbes, craft items and weapons. Build bases. Follow quests and find a cure for cancer. Don’t get eaten! If you enjoyed this game, see our list of games similar to Insiders.

73%Game Brain Score

Most mentioned positive aspects:story

Most mentioned negative aspects:gameplay, graphics

75% User Score Based on 80 reviews

Critic Score 65%Based on 1 reviews

Mars is under siege, and the colonists are fighting a losing battle. Assume the role of Blake, a private security operative who crash lands near the colony of Deadstone, following an outbreak on the Icarus space station. Care to guess who just landed the job of sheriff? If you enjoyed this game, see our list of games similar to Deadstone.

76%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:stability, grinding

76% User Score Based on 868 reviews

MarZ Rising is a tactical base defense game, which lets you discover a completely new gameplay experience of the tower defense genre! Build, manage and defend your martian base. Guide your crew safely through the thrilling campaign and solve the mystery of the undead. If you enjoyed this game, see our list of games similar to MarZ: Tactical Base Defense.

84%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

84% User Score Based on 1,214 reviews

Critic Score 85%Based on 2 reviews

"You are outgunned. You are massively outnumbered. You must win." These are your orders. Humanity has already fought its war against the machines -- and lost. AI death squads stand watch over every planet and every wormhole, the few remaining human settlements are held captive in orbiting bubbles, and the AIs have turned their attention outward, away from the galaxy, to alien threats or opportuni… If you enjoyed this game, see our list of games similar to AI War: Fleet Command.

74%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, stability

77% User Score Based on 900 reviews

Critic Score 66%Based on 3 reviews

Who needs backstory? Who needs resource-gathering? Diplomacy is so last year. Gratuitous Space Battles cuts right to the chase of sci-fi strategy games, and deals with large, completely unjustified space battles between huge opposing space fleets. If you enjoyed this game, see our list of games similar to Gratuitous Space Battles.

68%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding

87% User Score Based on 30 reviews

Rift Rangers is a sentai themed casual rogue-lite where you defend against an endless horde of dimensional creatures. Construct and upgrade your defensive turrets while dodging enemies! Find the right combination of turrets and upgrades to become an impenetrable fortress! If you enjoyed this game, see our list of games similar to Rift Rangers.

43%Game Brain Score

Most mentioned negative aspects:gameplay, story

65% User Score Based on 17 reviews

Become a young white blood cell in training and learn how they mature and fight against invading pathogens. Team up with other types of cells, with unique strengths and weaknesses, and overcome disease for good. To serve and protect the human body at all costs. If you enjoyed this game, see our list of games similar to Cells of Immunity.

86%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:monetization, stability

86% User Score Based on 7,560 reviews

Legion TD 2 is the first competitive tower defense for PC. It's the standalone successor to the popular Warcraft III mod, Legion TD, and brought to you by the same team. If you enjoyed this game, see our list of games similar to Legion TD 2.

51%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, music

56% User Score Based on 43 reviews

Prophour23 is a fast-paced, replayable real-time strategy. It's designed for short, quick plays. A single playthrough will take you about 15 minutes, if you're good. But the next one will be different. And another one as well. If you enjoyed this game, see our list of games similar to Prophour23.

78%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

78% User Score Based on 171 reviews

The White Laboratory is a sandbox style physics-based tower defense and RTS game in which you modularly build and command robotic structures. Use them to defend against or conquer other disobedient mechanical blocks on a facility floating in the atmosphere of a remote gas planet. If you enjoyed this game, see our list of games similar to The White Laboratory.

53%Game Brain Score

Most mentioned positive aspects:graphics, replayability

Most mentioned negative aspects:gameplay, story

53% User Score Based on 83 reviews

Gratuitous Tank Battles (GTB) is a unique hybrid of tower-defense, strategy, simulation and RTS. Set in an alternate history timeline where World War I never ends, you are the commander of allied forces fighting right up to the year 2114, where Mechs and lasers are used alongside tanks and rifles. The war continues across Europe, with the allied commanders still locked into the optimistic patrioti… If you enjoyed this game, see our list of games similar to Gratuitous Tank Battles.

73%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, stability

75% User Score Based on 759 reviews

Critic Score 65%Based on 1 reviews

Welcome to Soup Co., Astroworker! As an integral part of the Soup Co. family, your mission is to explore the remote planets in search of tasty ingredients to make the galaxies most delicious soups and then rocket them into the gullets of our hungry customers. But this isn't your typical soup kitchen - Astroworkers must battle against the planet's elements, alien plants and animals, and dastardly r… If you enjoyed this game, see our list of games similar to PixelJunk Nom Nom Galaxy.

AN ACTIVE INCREMENTAL TOWER DEFENSEHow to Turn Zombie combines incremental progression, tower defense pressure, and direct cursor-based combat. Attack cells directly with your cursor Defend your central Viral Core Harvest Biomass and unlock permanent mutations Build powerful upgrade synergies Adapt to new mechanics across different organs Face increasingly dangerous immune defenses and… If you enjoyed this game, see our list of games similar to How to Turn Zombie.

The peaceful takeover protocol is now active. The official report calls this a low-risk operation. The core device is charging, counterattack forces are closing in from every entrance, and the budget office still wants to know why you need another turret. Loop Defense is a single-player sci-fi tower defense game. Choose operations across a star map, build a defense for each site, and keep the co… If you enjoyed this game, see our list of games similar to Loop Defense: Acquisition Protocol.

Immunity is a fast-paced survival game where your body becomes the battlefield. Play as different immune cells, each with their own strengths, abilities, and playstyles, as you fight through waves of bacteria, viruses, and other threats. Every run pushes you to adapt, choose new mutations, and build a stronger defense before the infection overwhelms the organ you are trying to protect. As you su… If you enjoyed this game, see our list of games similar to Immunity.

The Horde has consumed humanity’s last line of defense. An unknown virus has swept across the globe. Cities have fallen, and civilization has collapsed. As a newly deployed operative, you are sent to the front lines of the infected zones, armed with weapons, tactical equipment, and defensive structures to protect humanity’s final hope against endless waves of the undead. Survive the Horde … If you enjoyed this game, see our list of games similar to Survive the Horde.

In Circuit Keep, your towers don't block anything. A wave spawns. Enemies pathfind straight across the grid toward your CORE. They walk over every module you placed. The only thing that makes them change direction is a wall. So you build the maze, line it with firepower, and force every wave down a path you chose. Then they start pushing back. INTRUSIONS THAT FIGHT BACKEach intrusion breaks you… If you enjoyed this game, see our list of games similar to Circuit Keep.

Build, upgrade and defend against an endless onslaught of cryptids being sent to destroy your tribe by the great Appalachian nightmare himself... the Rketari. If you enjoyed this game, see our list of games similar to Appalachian Onslaught.