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Games like Immune Response

Games like Immune Response

Games like Immune Response

Looking for games like Immune Response? Here are top casual shooter recommendations with a science fiction focus, selected from player-similarity data — start with Galaxy Highways, BloodDome99 or EON Trooper.

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  1. 96%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:replayability
    96% User Score Based on 55 reviews

    Galaxy Highways is a sci-fi space shooter where you're doing pirate raids into star systems inhabited by aliens. You destroy enemy ships, space stations, mother ships or bosses and complete all missions as soon as possible before enemy defense system destroys you with its powerful waves of attacks. If you enjoyed this game, see our list of games similar to Galaxy Highways.

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  2. 100%Game Brain Score
    Most mentioned positive aspects:graphics, music
    Most mentioned negative aspects:optimization
    100% User Score Based on 102 reviews

    80s/90s arcade cabinet meets modern horde-survival roguelike. Create unique builds, master 20+ weapons, and kill ever-growing hordes of contestants in the retro-futuristic gladiator gameshow BloodDome99. If you enjoyed this game, see our list of games similar to BloodDome99.

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  3. View Game
    63%Game Brain Score
    Most mentioned positive aspects:graphics, music
    Most mentioned negative aspects:gameplay, story
    100% User Score Based on 14 reviews

    EON Trooper on Steam! In EON Trooper, you join a galaxy at war, assuming the role of an elite soldier on missions behind enemy lines. Each mission is a unique challenge requiring careful planning and swift execution. Whether you are sabotaging enemy bases, stealing vital information, or simply surviving, you will need to utilize all tools and tactics at your disposal.EON Trooper combines intense … If you enjoyed this game, see our list of games similar to EON Trooper.

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  4. 87%Game Brain Score
    Most mentioned positive aspects:graphics, gameplay
    Most mentioned negative aspects:story, replayability
    92% User Score Based on 763 reviews
    Critic Score 72%Based on 2 reviews

    As the last surviving tank commander on Earth, single-handedly turn back the evil invading alien army, drive back the Titans across the Solar System, and defeat them on their homeworld... Titan Attacks has the same easy-to-learn and addictive gameplay of the classic arcade shoot 'em up If you enjoyed this game, see our list of games similar to Titan Attacks!.

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  5. 73%Game Brain Score
    Most mentioned positive aspects:story, graphics
    Most mentioned negative aspects:gameplay
    100% User Score Based on 24 reviews
    Critic Score 72%Based on 3 reviews

    As a threat from beyond looms over the solar system, Project Aether is ready to deploy! Take control of the Aether prototype in a variety of environments to combat this alien threat. If you enjoyed this game, see our list of games similar to Project AETHER: First Contact.

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  6. 68%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:grinding, replayability
    68% User Score Based on 174 reviews

    You are a friendly-but-deadly Mech on a journey searching for your missing pilot in this action-packed roguelite shooter. Choose your missions and rewards, research skills, equip expansions, mod your weapons, install plugins, customize your looks and stylishly cut your way through hordes of evil AI. If you enjoyed this game, see our list of games similar to Uragun.

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  7. 86%Game Brain Score
    Most mentioned positive aspects:story, music
    Most mentioned negative aspects:replayability, grinding
    93% User Score Based on 43 reviews

    You are Hadley Orah, the pilot of a mining craft from a South African space colony. Going through a portal with an untested piece of tech leaves you stranded and alone in a distant alien galaxy. An unlikely hero, you must portal jump your way home, with Nia as your guide, to defeat the DraadMek and save the universe. This game balances electrifying action with heart and soul. You’ll fight over… If you enjoyed this game, see our list of games similar to Hadley's Run: A Starship Saga.

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  8. 97%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:story, grinding
    97% User Score Based on 296 reviews

    Beat Invaders is a cool space Shoot-Em-Up. Blast your way through enemy fleets! Upgrade your ship with rockets & armor! Defeat the final boss! All to flashy neon musically charged visuals! If you enjoyed this game, see our list of games similar to Beat Invaders.

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  9. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, humor
    Most mentioned negative aspects:story, graphics
    95% User Score Based on 40 reviews

    Shoot, blast and slash through hordes of enemies in Rocking Pilot - a twin-stick shooter extravaganza inspired by arcade classics. If you enjoyed this game, see our list of games similar to Rocking Pilot.

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  10. Orbital Overdrive is a high-octane roguelite twin-stick arena shooter where you are pitted against hordes of relentless enemies on an orbit of a planet. Choose from hundreds of different abilities and weapons to create the deadliest build and smash the resistance! If you enjoyed this game, see our list of games similar to Orbital Overdrive.

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  11. It is the year 2197. Humanity has never been closer to immortality - there is no disease that can't be cured, no virus that can't be defeated. Until now. You will use cutting-edge technology to shrink yourself down and hunt down a new and mysterious virus that can't be defeated by any other means If you enjoyed this game, see our list of games similar to Herodes.

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  12. Defend the body in vaXinator, a fast-paced action roguelike! As the last white blood cell, unleash powerful abilities and antibodies to fight off waves of infections. Test your reflexes in this microscopic battle for survival. How long can you hold the line? If you enjoyed this game, see our list of games similar to vaXinator.

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  13. View Game
    96%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:replayability
    96% User Score Based on 57 reviews

    The machine world of Molybdion has fallen into disarray. As Nidhogg eats the root of the planet, unending wars rage on the surface, and machines fight endlessly in the sky above. Slice your way through hordes of metallic foes in five frantic levels, defeat fearsome bosses, and dodge countless bullets in this vintage vertical shoot 'em up. Key features: 2 playable characters for different pla… If you enjoyed this game, see our list of games similar to Lilac 0.

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  14. 95%Game Brain Score
    Most mentioned positive aspects:story, gameplay
    Most mentioned negative aspects:grinding, optimization
    95% User Score Based on 91 reviews

    Fast paced Top-down shooter! Smartly use IRCM to evade the constant barrage of bullets and missiles and destroy everything that stands in your way. If you enjoyed this game, see our list of games similar to Gigantes Ex Machina.

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  15. View Game
    64%Game Brain Score
    Most mentioned positive aspects:graphics, story
    Most mentioned negative aspects:gameplay, music
    64% User Score Based on 50 reviews

    A retro-inspired twin-stick shooter like they made back in the day. Guns, blood, and gore all in one nostalgia-looking package.Son of a Gun is an intense action packed top down shooter full of bullets, blood and explosions. Collect and manage your guns and grenades to fight swarming bugs, gigantic robots, slimy monsters and even space ghosts. Select one of 6 characters and upgrade them while progr… If you enjoyed this game, see our list of games similar to Son of a Gun.

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  16. 62%Game Brain Score
    Most mentioned positive aspects:graphics
    Most mentioned negative aspects:gameplay, story
    84% User Score Based on 25 reviews

    PhaigeX is a fast-paced "survivor-style" space shooter that tasks the player to contain a growing incursion of rogue AI-controlled units. Pilot a variety of ships, use a myriad of upgrades and lay down heavy firepower against the growing menace. If you enjoyed this game, see our list of games similar to PhaigeX: Hyperspace Survivors.

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  17. 92%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, monetization
    94% User Score Based on 1,294 reviews
    Critic Score 86%Based on 4 reviews

    Once a loyal knight, betrayed, and banished to the Abyss. A desecrated corpse inside reanimated armor. You rise to an eternal death. Branded KILL KNIGHT, you have one purpose - KILL THE LAST ANGEL.FIVE ELDRITCH LAYERSKILL, OR BE KILLEDDance with death in the Abyss, and unveil intricate layers of gameplay lurking beneath the surface. Exploit enemy weaknesses, enact brutal executions, weave through … If you enjoyed this game, see our list of games similar to KILL KNIGHT.

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  18. 89%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, monetization
    89% User Score Based on 2,570 reviews

    Time Wasters is a space shooter bullet heaven roguelite. Equip and upgrade weapons, destroy swarms of enemies, and collect Time & Space Cubes to bend the timeline to your advantage. If you enjoyed this game, see our list of games similar to Time Wasters.

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  19. View Game
    94%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, monetization
    94% User Score Based on 5,056 reviews

    Experience your music collection as never before with this intense music driven arcade shooter. Each of your songs will have its own unique ebb and flow based on the music. Power up your spaceship and watch as the music boosts your firepower. Unleash hell on the enemy ships when you max out with weapon pickups! Beat Hazard seamlessly mixes the love of gaming and music. Together they become great… If you enjoyed this game, see our list of games similar to Beat Hazard.

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  20. View Game
    61%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:graphics, replayability
    100% User Score Based on 12 reviews

    Fight to survive in this intense twin-stick shooter! Collect sentries, items, and drones as you unleash mayhem to defend a mining outpost from waves of goopy monsters that emerge from below. If you enjoyed this game, see our list of games similar to Minigunner.

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  21. 87%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:stability, grinding
    87% User Score Based on 1,254 reviews

    Experience your music collection as never before with this intense music driven arcade shooter. Each of your songs will have its own unique ebb and flow based on the music. If you enjoyed this game, see our list of games similar to Beat Hazard 2.

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  22. 71%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, replayability
    85% User Score Based on 40 reviews
    Critic Score 50%Based on 1 reviews

    An old robot named H-34-RT wakes up in a derelict space station orbiting his home planet. His civilization was destroyed long ago by evil O'Xelg, but he has yet to figure that out. After an initial shock, he decides to follow his old defense routines: that means fighting the invaders, even if he is alone now. Lazy Galaxy: Rebel Story is a challenging, squad-based shoot-em-up/bullet hell roguelite… If you enjoyed this game, see our list of games similar to Lazy Galaxy: Rebel Story.

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  23. View Game
    87%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, optimization
    87% User Score Based on 248 reviews

    Clean a galaxies from thousands of invaders! Nebula is an action, space shooter where your choices are making you progressively stronger against the endless waves of space enemies. If you enjoyed this game, see our list of games similar to Nebula.

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  24. 85%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story
    100% User Score Based on 42 reviews
    Critic Score 77%Based on 6 reviews

    A vertical arcade shoot'em up with an inventive teleport system, lots of fast-blazing action and explosions, tons of boss fights, a risk/reward based score system and a proper challenge for both veteran and new players of the genre. If you enjoyed this game, see our list of games similar to Sophstar.

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  25. 90%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:grinding, story
    91% User Score Based on 454 reviews
    Critic Score 84%Based on 2 reviews

    Blast hordes of alien ships into junk. Collect the scrap to upgrade your ship into an unstoppable force of destruction. Unlock new characters and weapons and upgrade your stats between runs. If you enjoyed this game, see our list of games similar to Void Scrappers.

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  26. 57%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:graphics
    87% User Score Based on 16 reviews
    Critic Score 58%Based on 1 reviews

    ShapeNeon Chaos is an old school style space-shooter. You are a ship facing off waves of deadly enemies. This game was made to give you a shot of adrenaline in a couple of minutes. Lots of bullets and neon in an arcade psychedelic shooter! If you enjoyed this game, see our list of games similar to ShapeNeon Chaos.

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  27. View Game
    95%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, optimization
    98% User Score Based on 691 reviews
    Critic Score 80%Based on 1 reviews

    BLUE REVOLVER is a fresh new shoot-em-up built for newcomers and psychos alike. An adaptive difficulty system tailors the game to your skill level as you fight and flourish to evade the maniac environmental force, "Blue Revolver"! If you enjoyed this game, see our list of games similar to BLUE REVOLVER.

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  28. View Game
    94%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:story, optimization
    97% User Score Based on 1,282 reviews
    Critic Score 80%Based on 1 reviews

    Waves is a twin stick shooter that can be played by anyone, but with a high enough skill threshold to keep even the most hardened shooter fan entertained. Clear the arena of enemies while racking up a big fat Combo with swift kills and well timed Bombs. If it all gets a bit too much you can use your Time Buffer to slow down the action and turn defeat into victory. Players can compete across seven… If you enjoyed this game, see our list of games similar to Waves.

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  29. 61%Game Brain Score
    Most mentioned positive aspects:graphics, music
    Most mentioned negative aspects:gameplay
    100% User Score Based on 12 reviews

    ⚡ Circuit OverloadCircuit Overload is a fast-paced arcade bullet-hell shooter built around precision, escalation, and pure action. You control a combat unit inside a hostile digital environment, facing endless waves of enemies and increasingly complex attack patterns. The longer you survive, the faster and more chaotic the screen becomes — pushing your reflexes, positioning, and decision-making t… If you enjoyed this game, see our list of games similar to Circuit Overload.

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  30. Never Immortal Never Immortal is a 2D multiplayer topdown shooter featuring two different exciting gamemodes: Wave Survival and Zombie Mystery Wave Survival (PvE) Can be played alone or with friends In the Wave Survival gamemode, you need to survive waves of zombies to avoid being eaten alive. You can try to survive as many waves as you can or you can also try to beat the map. You can also bu… If you enjoyed this game, see our list of games similar to Never Immortal.

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  31. The Merlian Empire has seized control of the Five Worlds. With the galaxy under threat, hope lies in the hands of the Starlight Squad—a fearless team of heroines ready to fight back. Starlight Squad is a fast-paced vertical shoot 'em up featuring handcrafted pixel art, epic boss battles, and explosive arcade action. Choose one of three playable pilots—each with a unique ship, playstyle, and speci… If you enjoyed this game, see our list of games similar to Starlight Squad.

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  32. Enter a neon-charged battleground where survival meets explosive energy in this retro, space-themed twin-stick shooter! As you dance through waves of geometric adversaries, each defeated enemy leaves behind a deadly debris field—lure other enemies into these hazard zones to trigger devastating chain reactions and score multipliers. Snag powerful upgrades that temporarily boost your ship's offens… If you enjoyed this game, see our list of games similar to Electro Havoc.

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  33. Defeat the Virus with Your Wig!!! ~ About the Game ~Zurarararush!!! is a fast, funny, and deeply satisfying twin-stick shooter where you fight viruses using your ultimate weapon — a wig (ZURA)! Play as a microscopic doctor wearing a Micro Suit, equipping all kinds of ZURAs (wigs) to battle countless mutating viruses inside the human body. The endless barrage of enemies and bullets will stimulate… If you enjoyed this game, see our list of games similar to Zurarararush!!!.

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  34. Earth: 9000 a new indie Bullet Hell, Twin Stick, Rogue-Lite mashup. You command Earth and all her defenses. Your mission; stop a never ending onslaught of alien invaders and try to keep your mind intact while your senses are brutally overwhelmed. Unlock dozens of weapons and even more upgrades as you gain research from defeating enemies and special events. You will be defeated, but that isn't the … If you enjoyed this game, see our list of games similar to Earth: 9000.

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  35. 69%Game Brain Score
    Most mentioned positive aspects:story, music
    100% User Score Based on 20 reviews

    B.O.T.S. and the Robofriends is a twin-stick arcade style action game set in the year 2083. Play by yourself or with friends, picking from one of four robot characters with unique attributes and attacks. Play as BRI, RED, TOM, and STU, fighting back the hoard of enemies attacking your home. If you enjoyed this game, see our list of games similar to B.O.T.S. and the Robofriends.

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  36. Circus Interstellar is a brutal arcade shooter featuring high-octane action, and killer music! Earth voyagers encounter a sadistic alien race with a terrifying clownish appearance and a nasty appetite. Will the survivors escape the gory circus? Or will they be assimilated like all the rest? If you enjoyed this game, see our list of games similar to Circus Interstellar.

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  37. 93%Game Brain Score
    Most mentioned positive aspects:music, graphics
    Most mentioned negative aspects:grinding, optimization
    93% User Score Based on 75 reviews

    Rhythm Storm is a roguelike bullet heaven with stunning vector graphics, rhythmic action, and overwhelming swarms of enemies. Your vehicle aims and fires automatically while everything else dances and moves to the beat in this spectacular audio-visual experience. If you enjoyed this game, see our list of games similar to Rhythm Storm.

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  38. 95%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, grinding
    95% User Score Based on 133 reviews

    Welcome to Breakpoint, a twin-stick slasher that provides all the hectic action of a bullet hell with the crunchy satisfaction of melee combat. Unlike other twin stick games, there are zero ranged attacks in Breakpoint. You have to control the battlefield with a variety of physical attacks. Slice, smash, and crush your way through waves of enemies to defeat the swarm. Move and groove your way thro… If you enjoyed this game, see our list of games similar to Breakpoint.

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  39. 94%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    97% User Score Based on 10,045 reviews
    Critic Score 80%Based on 1 reviews

    Nova Drift distills the mechanical depth of an action RPG into classic arcade space combat. Control an endlessly evolving bio-mechanical ship, face legions of strange and deadly foes, and ride the wake of a dying star across the void. If you enjoyed this game, see our list of games similar to Nova Drift.

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  40. Old School Arcade Space Shooting Combat Play it old school like being back in the arcade in a fluid top-down space shooter which feels as smooth as buttery popcorn! Have fun blasting away old school style as you jam out to some rockin' 8-bit, 16-bit, and orchestral tunes just like playing arcade games at the movie theater! Unleash The Flavors of Your Popcorn Arsenal! Blast away the evil Nebula Em… If you enjoyed this game, see our list of games similar to Popcorn Rocket.

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  41. View Game
    77%Game Brain Score
    Most mentioned positive aspects:gameplay, emotional
    Most mentioned negative aspects:graphics, music
    82% User Score Based on 45 reviews

    Develop the ultimate vaccine in Metavaxx, the world's first minesweeper shooter! Train your own new vaccine in body samples, either by shooting down the virus agents hidden in infected cells, or by isolating those cells, only clearing the healthy cells around them. You win when there are only healthy cells OR only infected cells remaining. Your vaccine's progress depends on how many remaining cel… If you enjoyed this game, see our list of games similar to Metavaxx.

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  42. View Game
    91%Game Brain Score
    Most mentioned positive aspects:story, graphics
    Most mentioned negative aspects:optimization, stability
    91% User Score Based on 526 reviews

    Get injected into the microscopic world of BioGun. Face viral threats and winding corridors on your mission to save man’s best friend from the inside. Will you be the vaccine to save dog-kind from extinction or will DocX have to return to the drawing board? If you enjoyed this game, see our list of games similar to BioGun.

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  43. 98%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, story
    98% User Score Based on 274 reviews

    A fast-paced paint 'em up roguelike where each level you beat becomes a masterpiece to add to your colorful collection. If you enjoyed this game, see our list of games similar to Antipaint.

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  44. 71%Game Brain Score
    Most mentioned positive aspects:replayability, gameplay
    Most mentioned negative aspects:graphics, music
    100% User Score Based on 22 reviews

    Embark on an exciting journey in this thrilling bug blasting adventure! Choose one of four playable characters and join the battle to free your fellow elves from the grasp of a wicked spider army. Each playable character comes with their own set of unique abilities and strengths, giving you the freedom to tackle obstacles in your own way. But beware, your foes won't make your mission easy. In addi… If you enjoyed this game, see our list of games similar to Little Elf Tanks.

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  45. 88%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    88% User Score Based on 678 reviews

    A twin stick shooter without the twin stick, Gunlocked is a sci-fi action roguelike about careful positioning and upgrade selection. Manage unique targeting systems across multiple weapons and upgrades, as you battle legions of alien ships, and then do it all over again! If you enjoyed this game, see our list of games similar to Gunlocked.

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  46. 95%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:grinding, optimization
    95% User Score Based on 2,626 reviews

    2121 A.D, with no escape options, Akane prepares for her final battle in the rain-soaked neon streets of Mega-Tokyo. Akane is an arena arcade slasher. Take out as many yakuza as possible, slashing and shooting in a one-hit-one-kill fight to the death. If you enjoyed this game, see our list of games similar to Akane.

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  47. View Game
    93%Game Brain Score
    Most mentioned positive aspects:music, gameplay
    Most mentioned negative aspects:story
    94% User Score Based on 51 reviews
    Critic Score 86%Based on 1 reviews

    SCORCHING TECHBEAT ACTION! A frantic combo-based score attack shooter with roguelite elements. Make combos to earn more time. Master all weapons and defeat a raving mad machine. 100% arcade action. Online ranking. Lots of achievements. A Dual Gunstrike spin off. If you enjoyed this game, see our list of games similar to TechBeat Heart.

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  48. 54%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:music, story
    54% User Score Based on 78 reviews
    Critic Score 55%Based on 6 reviews

    Circuit Breakers is an action racing game. Use a mighty array of devastating weaponry and rack up combos and upgrades to inflict maximum mayhem on the robot army, fighting your way through its massive manufacturing plant. If you enjoyed this game, see our list of games similar to Circuit Breakers.

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  49. 76%Game Brain Score
    Most mentioned positive aspects:gameplay, music
    Most mentioned negative aspects:story, grinding
    76% User Score Based on 127 reviews
    Critic Score 75%Based on 2 reviews

    FIGHT IN EVER CHANGING SPACE BATTLES! Run through the universe, discover the numerous perks/consumables and their synergistic effects. Explore the randomly-generated galaxy to find merchants,... If you enjoyed this game, see our list of games similar to Stellar Interface.

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  50. View Game
    62%Game Brain Score
    Most mentioned positive aspects:gameplay, story
    Most mentioned negative aspects:stability, grinding
    63% User Score Based on 329 reviews
    Critic Score 61%Based on 7 reviews

    Tower 57 is a fast-paced neo-retro shooter where cooperation is as important as your ammo capacity. As a member of an extraordinary task force fight your way through a dieselpunk megatower and uncover its hidden secrets. If you enjoyed this game, see our list of games similar to Tower 57.

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