Games like Immune Response

96%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:replayability

96% User Score Based on 55 reviews

Galaxy Highways is a sci-fi space shooter where you're doing pirate raids into star systems inhabited by aliens. You destroy enemy ships, space stations, mother ships or bosses and complete all missions as soon as possible before enemy defense system destroys you with its powerful waves of attacks. If you enjoyed this game, see our list of games similar to Galaxy Highways.

It is the year 2197. Humanity has never been closer to immortality - there is no disease that can't be cured, no virus that can't be defeated. Until now. You will use cutting-edge technology to shrink yourself down and hunt down a new and mysterious virus that can't be defeated by any other means If you enjoyed this game, see our list of games similar to Herodes.

100%Game Brain Score

Most mentioned positive aspects:graphics, music

Most mentioned negative aspects:optimization

100% User Score Based on 102 reviews

80s/90s arcade cabinet meets modern horde-survival roguelike. Create unique builds, master 20+ weapons, and kill ever-growing hordes of contestants in the retro-futuristic gladiator gameshow BloodDome99. If you enjoyed this game, see our list of games similar to BloodDome99.

96%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding, stability

96% User Score Based on 1,665 reviews

You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions. If you enjoyed this game, see our list of games similar to Pathogenic.

Defend the body in vaXinator, a fast-paced action roguelike! As the last white blood cell, unleash powerful abilities and antibodies to fight off waves of infections. Test your reflexes in this microscopic battle for survival. How long can you hold the line? If you enjoyed this game, see our list of games similar to vaXinator.

Survive the swarm. Lure drones into traps, upgrade your defenses, and hold out as long as you can. Just skill, strategy, and chaos as the horde grows deadlier every minute. Never stop. Buffs grant hope, debuffs take it away. How long can you survive? Features: Kite swarms Bait enemies into traps Upgrade your skills Find Repair Kits and Upgrade your defenses Explore to locate unique one time usable… If you enjoyed this game, see our list of games similar to Swarm Me.

Gunclone Arena is a top-down looter-shooter roguelite. Fight as a super-clone that can wield 6 weapons, a Beam and Shield in a dystopian TV show! Loot thousands of weapon variants with ricochet, detonate, shock, pierce and more. Stack build-changing Mods. Notice: Escape is grounds for perma-recycle. If you enjoyed this game, see our list of games similar to Gunclone Arena.

62%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:gameplay, story

84% User Score Based on 25 reviews

PhaigeX is a fast-paced "survivor-style" space shooter that tasks the player to contain a growing incursion of rogue AI-controlled units. Pilot a variety of ships, use a myriad of upgrades and lay down heavy firepower against the growing menace. If you enjoyed this game, see our list of games similar to PhaigeX: Hyperspace Survivors.

89%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, monetization

89% User Score Based on 2,570 reviews

Time Wasters is a space shooter bullet heaven roguelite. Equip and upgrade weapons, destroy swarms of enemies, and collect Time & Space Cubes to bend the timeline to your advantage. If you enjoyed this game, see our list of games similar to Time Wasters.

87%Game Brain Score

Most mentioned positive aspects:graphics, gameplay

Most mentioned negative aspects:story, replayability

92% User Score Based on 763 reviews

Critic Score 72%Based on 2 reviews

As the last surviving tank commander on Earth, single-handedly turn back the evil invading alien army, drive back the Titans across the Solar System, and defeat them on their homeworld... Titan Attacks has the same easy-to-learn and addictive gameplay of the classic arcade shoot 'em up If you enjoyed this game, see our list of games similar to Titan Attacks!.

91%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:story, replayability

93% User Score Based on 257 reviews

Critic Score 80%Based on 1 reviews

Ubermosh: Omega, the apex of Walter Machado's Cult Classic series Ubermosh. If you enjoyed this game, see our list of games similar to UBERMOSH:OMEGA.

90%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, grinding

100% User Score Based on 49 reviews

Critic Score 77%Based on 6 reviews

A vertical arcade shoot'em up with an inventive teleport system, lots of fast-blazing action and explosions, tons of boss fights, a risk/reward based score system and a proper challenge for both veteran and new players of the genre. If you enjoyed this game, see our list of games similar to Sophstar.

73%Game Brain Score

Most mentioned positive aspects:story, graphics

Most mentioned negative aspects:gameplay

100% User Score Based on 24 reviews

Critic Score 72%Based on 3 reviews

As a threat from beyond looms over the solar system, Project Aether is ready to deploy! Take control of the Aether prototype in a variety of environments to combat this alien threat. If you enjoyed this game, see our list of games similar to Project AETHER: First Contact.

Orbital Overdrive is a high-octane roguelite twin-stick arena shooter where you are pitted against hordes of relentless enemies on an orbit of a planet. Choose from hundreds of different abilities and weapons to create the deadliest build and smash the resistance! If you enjoyed this game, see our list of games similar to Orbital Overdrive.

95%Game Brain Score

Most mentioned positive aspects:music, graphics

Most mentioned negative aspects:replayability, grinding

98% User Score Based on 53 reviews

Critic Score 85%Based on 2 reviews

Take down hordes of alien invaders with your Power Shot, Truxton Beam, Thunder Laser, Homing Shot, Star‑mine Shot, and more! Don't forget to breathe as you face off against gigantic bosses in the ultimate battle for humanity’s survival! If you enjoyed this game, see our list of games similar to Truxton Extreme.

76%Game Brain Score

Most mentioned positive aspects:music, graphics

Most mentioned negative aspects:gameplay, replayability

97% User Score Based on 30 reviews

Forget bullets. In Cyberpulse, your weapon is physics. Grab viruses with cyberkinetic forces. Slam them into each other. Fling them into molten firewalls. Yank an incoming enemy and use its momentum against the next wave. Every enemy on screen is a projectile waiting to happen — if you're fast enough to see it. Cyberpulse is a twin-stick arcade shooter that inverts the genre's core rule: instead… If you enjoyed this game, see our list of games similar to Cyberpulse.

68%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, replayability

68% User Score Based on 174 reviews

You are a friendly-but-deadly Mech on a journey searching for your missing pilot in this action-packed roguelite shooter. Choose your missions and rewards, research skills, equip expansions, mod your weapons, install plugins, customize your looks and stylishly cut your way through hordes of evil AI. If you enjoyed this game, see our list of games similar to Uragun.

71%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:replayability, graphics

71% User Score Based on 58 reviews

Bullet heaven, deckbuilding, and strategy – Moon Watch is a wild new mix from the creators of Backpack Hero! Master your tactics, not reflexes: stop time at will, craft a killer deck, stop the horde in their tracks! If you enjoyed this game, see our list of games similar to Moon Watch.

63%Game Brain Score

Most mentioned positive aspects:graphics, music

Most mentioned negative aspects:gameplay, story

100% User Score Based on 14 reviews

EON Trooper on Steam! In EON Trooper, you join a galaxy at war, assuming the role of an elite soldier on missions behind enemy lines. Each mission is a unique challenge requiring careful planning and swift execution. Whether you are sabotaging enemy bases, stealing vital information, or simply surviving, you will need to utilize all tools and tactics at your disposal.EON Trooper combines intense … If you enjoyed this game, see our list of games similar to EON Trooper.

92%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, monetization

94% User Score Based on 1,294 reviews

Critic Score 86%Based on 4 reviews

Once a loyal knight, betrayed, and banished to the Abyss. A desecrated corpse inside reanimated armor. You rise to an eternal death. Branded KILL KNIGHT, you have one purpose - KILL THE LAST ANGEL.FIVE ELDRITCH LAYERSKILL, OR BE KILLEDDance with death in the Abyss, and unveil intricate layers of gameplay lurking beneath the surface. Exploit enemy weaknesses, enact brutal executions, weave through … If you enjoyed this game, see our list of games similar to KILL KNIGHT.

77%Game Brain Score

Most mentioned positive aspects:gameplay, emotional

Most mentioned negative aspects:graphics, music

82% User Score Based on 45 reviews

Develop the ultimate vaccine in Metavaxx, the world's first minesweeper shooter! Train your own new vaccine in body samples, either by shooting down the virus agents hidden in infected cells, or by isolating those cells, only clearing the healthy cells around them. You win when there are only healthy cells OR only infected cells remaining. Your vaccine's progress depends on how many remaining cel… If you enjoyed this game, see our list of games similar to Metavaxx.

86%Game Brain Score

Most mentioned positive aspects:story, music

Most mentioned negative aspects:replayability, grinding

93% User Score Based on 43 reviews

You are Hadley Orah, the pilot of a mining craft from a South African space colony. Going through a portal with an untested piece of tech leaves you stranded and alone in a distant alien galaxy. An unlikely hero, you must portal jump your way home, with Nia as your guide, to defeat the DraadMek and save the universe. This game balances electrifying action with heart and soul. You’ll fight over… If you enjoyed this game, see our list of games similar to Hadley's Run: A Starship Saga.

94%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:grinding, monetization

94% User Score Based on 5,056 reviews

Experience your music collection as never before with this intense music driven arcade shooter. Each of your songs will have its own unique ebb and flow based on the music. Power up your spaceship and watch as the music boosts your firepower. Unleash hell on the enemy ships when you max out with weapon pickups! Beat Hazard seamlessly mixes the love of gaming and music. Together they become great… If you enjoyed this game, see our list of games similar to Beat Hazard.

61%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, replayability

100% User Score Based on 12 reviews

Fight to survive in this intense twin-stick shooter! Collect sentries, items, and drones as you unleash mayhem to defend a mining outpost from waves of goopy monsters that emerge from below. If you enjoyed this game, see our list of games similar to Minigunner.

76%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:story, grinding

76% User Score Based on 127 reviews

FIGHT IN EVER CHANGING SPACE BATTLES! Run through the universe, discover the numerous perks/consumables and their synergistic effects. Explore the randomly-generated galaxy to find merchants,... If you enjoyed this game, see our list of games similar to Stellar Interface.

87%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:stability, grinding

87% User Score Based on 1,254 reviews

Experience your music collection as never before with this intense music driven arcade shooter. Each of your songs will have its own unique ebb and flow based on the music. If you enjoyed this game, see our list of games similar to Beat Hazard 2.

24%Game Brain Score

Most mentioned positive aspects:story, graphics

Most mentioned negative aspects:grinding

40% User Score Based on 10 reviews

INSPACE 2980 is a stylish and dynamic SHMUP from the 16-bit era of games consoles and arcade machines. Take part in an exciting adventure and save the galaxy! Once again! Dynamic battles. The endless stream of various enemies won’t let you rest until the very end of the battle. Upgrades and power-ups. Ten characteristics of the ship, which can be improved, as well as many power-ups that will e… If you enjoyed this game, see our list of games similar to INSPACE 2980.

87%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, optimization

87% User Score Based on 248 reviews

Clean a galaxies from thousands of invaders! Nebula is an action, space shooter where your choices are making you progressively stronger against the endless waves of space enemies. If you enjoyed this game, see our list of games similar to Nebula.

76%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, story

83% User Score Based on 590 reviews

Critic Score 40%Based on 1 reviews

Over 9000 Zombies! is top-down arcade action blown out of all reasonable proportions. An endless horde of zombies is coming your way, how long can you survive? If you enjoyed this game, see our list of games similar to Over 9000 Zombies!.

90%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding, story

91% User Score Based on 454 reviews

Critic Score 84%Based on 2 reviews

Blast hordes of alien ships into junk. Collect the scrap to upgrade your ship into an unstoppable force of destruction. Unlock new characters and weapons and upgrade your stats between runs. If you enjoyed this game, see our list of games similar to Void Scrappers.

57%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics

87% User Score Based on 16 reviews

Critic Score 58%Based on 1 reviews

ShapeNeon Chaos is an old school style space-shooter. You are a ship facing off waves of deadly enemies. This game was made to give you a shot of adrenaline in a couple of minutes. Lots of bullets and neon in an arcade psychedelic shooter! If you enjoyed this game, see our list of games similar to ShapeNeon Chaos.

44%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, music

53% User Score Based on 17 reviews

Critic Score 76%Based on 1 reviews

Use your powers and find your playstyle to survive in Boiling Bolt, an immersive and explosive shoot-em-up! Slow down the time to make combos and enjoy the stunning 3D graphics. Help June to save the world alone or with a friend. If you enjoyed this game, see our list of games similar to Boiling Bolt.

95%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:grinding, optimization

98% User Score Based on 691 reviews

Critic Score 80%Based on 1 reviews

BLUE REVOLVER is a fresh new shoot-em-up built for newcomers and psychos alike. An adaptive difficulty system tailors the game to your skill level as you fight and flourish to evade the maniac environmental force, "Blue Revolver"! If you enjoyed this game, see our list of games similar to BLUE REVOLVER.

94%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:story, optimization

97% User Score Based on 1,282 reviews

Critic Score 80%Based on 1 reviews

Waves is a twin stick shooter that can be played by anyone, but with a high enough skill threshold to keep even the most hardened shooter fan entertained. Clear the arena of enemies while racking up a big fat Combo with swift kills and well timed Bombs. If it all gets a bit too much you can use your Time Buffer to slow down the action and turn defeat into victory. Players can compete across seven… If you enjoyed this game, see our list of games similar to Waves.

Never Immortal Never Immortal is a 2D multiplayer topdown shooter featuring two different exciting gamemodes: Wave Survival and Zombie Mystery Wave Survival (PvE) Can be played alone or with friends In the Wave Survival gamemode, you need to survive waves of zombies to avoid being eaten alive. You can try to survive as many waves as you can or you can also try to beat the map. You can also bu… If you enjoyed this game, see our list of games similar to Never Immortal.

The Merlian Empire has seized control of the Five Worlds. With the galaxy under threat, hope lies in the hands of the Starlight Squad—a fearless team of heroines ready to fight back. Starlight Squad is a fast-paced vertical shoot 'em up featuring handcrafted pixel art, epic boss battles, and explosive arcade action. Choose one of three playable pilots—each with a unique ship, playstyle, and speci… If you enjoyed this game, see our list of games similar to Starlight Squad.

Earth: 9000 a new indie Bullet Hell, Twin Stick, Rogue-Lite mashup. You command Earth and all her defenses. Your mission; stop a never ending onslaught of alien invaders and try to keep your mind intact while your senses are brutally overwhelmed. Unlock dozens of weapons and even more upgrades as you gain research from defeating enemies and special events. You will be defeated, but that isn't the … If you enjoyed this game, see our list of games similar to Earth: 9000.

69%Game Brain Score

Most mentioned positive aspects:story, music

100% User Score Based on 20 reviews

B.O.T.S. and the Robofriends is a twin-stick arcade style action game set in the year 2083. Play by yourself or with friends, picking from one of four robot characters with unique attributes and attacks. Play as BRI, RED, TOM, and STU, fighting back the hoard of enemies attacking your home. If you enjoyed this game, see our list of games similar to B.O.T.S. and the Robofriends.

Pure Retro Arcade InsanityManga heart. Synthwave soul. Arcade fury. Neon Breaker: Endless Arcade delivers the fast, fun, bright spectacle and score-chasing obsession of classic arcade side scrolling shmup cabinets soulfully recreated in modern 3d with the action turned up to eleven. Cell shaded and manga anime inspired from the famous 80s mecha era, Neon Breaker is an unapologetic nostalgia acti… If you enjoyed this game, see our list of games similar to Neon Breaker: Endless Arcade.

96%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:replayability

96% User Score Based on 57 reviews

The machine world of Molybdion has fallen into disarray. As Nidhogg eats the root of the planet, unending wars rage on the surface, and machines fight endlessly in the sky above. Slice your way through hordes of metallic foes in five frantic levels, defeat fearsome bosses, and dodge countless bullets in this vintage vertical shoot 'em up. Key features: 2 playable characters for different pla… If you enjoyed this game, see our list of games similar to Lilac 0.

91%Game Brain Score

Most mentioned positive aspects:music, graphics

Most mentioned negative aspects:story, grinding

91% User Score Based on 152 reviews

Brace yourself for the explosive action of Let Them Come: Onslaught, a fast-paced roguelite shooter where survival means adapting, upgrading, and unleashing devastating firepower. Battle relentless alien swarms across procedurally generated stages, unlocking new weapons and stacking brutal upgrades with every run. Whether you're clearing the screen with flamethrowers, orbital strikes, or Photon Sa… If you enjoyed this game, see our list of games similar to Let Them Come: Onslaught.

93%Game Brain Score

Most mentioned positive aspects:music, graphics

Most mentioned negative aspects:grinding, optimization

93% User Score Based on 75 reviews

Rhythm Storm is a roguelike bullet heaven with stunning vector graphics, rhythmic action, and overwhelming swarms of enemies. Your vehicle aims and fires automatically while everything else dances and moves to the beat in this spectacular audio-visual experience. If you enjoyed this game, see our list of games similar to Rhythm Storm.

90%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:graphics, story

90% User Score Based on 293 reviews

Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun! Have fun surviving Spartan! Spartan Survivors includes 10 playable levels 5 difficulty modes 21 weapons for a total of 105 evolutions // 14 perks with 56 upgrades 8 playable characters with their unique weapons, perks & stats Unlock Custom Game to tailor the game th… If you enjoyed this game, see our list of games similar to Spartan Survivors.

95%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:story, grinding

95% User Score Based on 133 reviews

Welcome to Breakpoint, a twin-stick slasher that provides all the hectic action of a bullet hell with the crunchy satisfaction of melee combat. Unlike other twin stick games, there are zero ranged attacks in Breakpoint. You have to control the battlefield with a variety of physical attacks. Slice, smash, and crush your way through waves of enemies to defeat the swarm. Move and groove your way thro… If you enjoyed this game, see our list of games similar to Breakpoint.

84%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:optimization, atmosphere

84% User Score Based on 215 reviews

Sodaman, he's a space agent. He must stop the hostile aliens trying to destroy the universe and save the carbonated drinks they destroyed. Maybe you should help him out? If you enjoyed this game, see our list of games similar to Sodaman.

64%Game Brain Score

Most mentioned positive aspects:graphics, story

Most mentioned negative aspects:gameplay, music

64% User Score Based on 50 reviews

A retro-inspired twin-stick shooter like they made back in the day. Guns, blood, and gore all in one nostalgia-looking package.Son of a Gun is an intense action packed top down shooter full of bullets, blood and explosions. Collect and manage your guns and grenades to fight swarming bugs, gigantic robots, slimy monsters and even space ghosts. Select one of 6 characters and upgrade them while progr… If you enjoyed this game, see our list of games similar to Son of a Gun.

94%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:story, grinding

97% User Score Based on 10,045 reviews

Critic Score 80%Based on 1 reviews

Nova Drift distills the mechanical depth of an action RPG into classic arcade space combat. Control an endlessly evolving bio-mechanical ship, face legions of strange and deadly foes, and ride the wake of a dying star across the void. If you enjoyed this game, see our list of games similar to Nova Drift.

48%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, replayability

63% User Score Based on 27 reviews

Wishlist on Steam to be notified when the full version is released. Annihilate endless swarms of enemies with devastating weaponry, survive this Kinetic Storm by unlocking powerful skills and upgrades. This sci-fi action roguelike will test your skills like no other, with responsive twin-stick controls and unique enemy design. If you enjoyed this game, see our list of games similar to Kinetic Storm.

91%Game Brain Score

Most mentioned positive aspects:story, graphics

Most mentioned negative aspects:optimization, stability

91% User Score Based on 526 reviews

Get injected into the microscopic world of BioGun. Face viral threats and winding corridors on your mission to save man’s best friend from the inside. Will you be the vaccine to save dog-kind from extinction or will DocX have to return to the drawing board? If you enjoyed this game, see our list of games similar to BioGun.

98%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:grinding, story

98% User Score Based on 274 reviews

A fast-paced paint 'em up roguelike where each level you beat becomes a masterpiece to add to your colorful collection. If you enjoyed this game, see our list of games similar to Antipaint.