Games like Colony on the Run

61%Game Brain Score

Most mentioned positive aspects:music, story

100% User Score Based on 12 reviews

Listeria Wars is a tactical strategy where we protect the hero’s body from various infections and viruses by controlling the troops of the immune system. We can observe his personal life and even influence it with side effects. If you enjoyed this game, see our list of games similar to Listeria Wars.

85%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:replayability, story

85% User Score Based on 484 reviews

Sipho is an action survival game with an intricate building system. Grow your own creature and take over the local ecosystem. Fight, grow, survive, dominate. If you enjoyed this game, see our list of games similar to Sipho.

65%Game Brain Score

Most mentioned positive aspects:atmosphere, emotional

Most mentioned negative aspects:story, gameplay

88% User Score Based on 25 reviews

Space Tales is a sci-fi RTS where you build fortified bases, manage resources, and command retro-futuristic armies. Adapt to deadly alien factions, capture huge monsters and turn them into powerful allies as humanity fights to survive among the stars. If you enjoyed this game, see our list of games similar to Space Tales.

80%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:replayability, grinding

80% User Score Based on 523 reviews

Join the wonderful and amazing world of microorganisms. If you enjoyed this game, see our list of games similar to Microcosmum: survival of cells.

Survive an endless undead horde in this brutal auto-battling roguelike. Slash, upgrade, and evolve your arsenal as chaos unfolds to the pulse of an industrial metal soundtrack. Contagion Protocol is fast, bloody, and built for replayability. If you enjoyed this game, see our list of games similar to Contagion Protocol.

A 100-level arcade survival war where every mistake feeds the swarm. Hunt high-value spaceships, protect limited turret reserves, research vital tech, and evolve faster than the aliens on the road to the Mothership. If you enjoyed this game, see our list of games similar to Invaders Evolutions.

Grass Cutting Game - Survive endless enemy waves! Choose from 3 weapons: Assault Rifle, Poison Field, or Light Saber. Upgrade through 5 levels + ultimate forms. Stunning particle effects! If you enjoyed this game, see our list of games similar to 割草游戏 mow grass.

78%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:atmosphere, grinding

88% User Score Based on 40 reviews

In Everwarder there's you, and a procedurally-generated world covered in darkness. Touch it - and it will spawn a creature that will try to destroy your most precious thing – a crystal with your friend trapped inside. Every run starts with your crystal and a supply of energy. Then it's up to you how to fight the darkness. Do you steadily expand, clearing the darkness, harvesting its energy, and ca… If you enjoyed this game, see our list of games similar to Everwarder.

51%Game Brain Score

Most mentioned positive aspects:graphics, humor

Most mentioned negative aspects:gameplay, music

56% User Score Based on 43 reviews

Prophour23 is a fast-paced, replayable real-time strategy. It's designed for short, quick plays. A single playthrough will take you about 15 minutes, if you're good. But the next one will be different. And another one as well. If you enjoyed this game, see our list of games similar to Prophour23.

Pilot your ship, master inertia, and turn the tide amid heavy enemy fire with Extreme Dodge and up to 6 active abilities. Grow stronger through consecutive battles in Survival Mode, or collect ships, upgrade gear, and uncover the universe’s past and hidden truths in Story Mode. If you enjoyed this game, see our list of games similar to Pioneer Venture: Echo.

Intergalactic Defenders is a retro-inspired space shooter combining fast-paced arcade action with rogue-like progression and handcrafted pixel art. If you love classic shoot 'em up (shmup) gameplay with modern upgrades and replayability, this is your next obsession. The year is 2187. Humanity's colonies are under siege. The alien Caedons have launched a merciless invasion — and you're the United … If you enjoyed this game, see our list of games similar to Intergalactic Defenders.

Twin-stick space combat roguelite with 12 abilities, 5 reality-warping ultimates, and 20+ enemy factions that each fight differently. Permanent upgrades that stack across hundreds of hours. Quick missions, deep progression, zero runs wasted. If you enjoyed this game, see our list of games similar to Void Breach.

80%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding

100% User Score Based on 31 reviews

You are a Lunar Knight of the blood moon, and tonight is your night. It's time for violence. Slay the twisted horrors conjured by the moon in this horde survival roguelite. Gain experience, grow stronger, and synergize your weapons to crush the enemy forces and survive the night. If you enjoyed this game, see our list of games similar to Bloodmoon Survivors.

91%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:graphics, music

91% User Score Based on 365 reviews

Bioprototype, a Roguelike & Skill Customizing Rhapsody! This is an auto-bomber with programming elements. Customize your character skills with visual programming, utilize enemy organs to finish the mutation, and construct the ultimate prototype, one can survive in the endless wave of flesh. If you enjoyed this game, see our list of games similar to Bioprototype.

81%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, story

81% User Score Based on 648 reviews

The necromancer simulator is back. Assemble your undead from different body parts, combining the abilities of various fantasy races. Upgrade your tower and give it a unique look. Fight your way through hordes of enemies in a procedurally generated world and take Titans under control. Features Undead with SuperpowersAssemble your undead from the body parts of various fantasy races, unlocking countl… If you enjoyed this game, see our list of games similar to Necrosmith 2.

75%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, music

75% User Score Based on 478 reviews

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy. If you enjoyed this game, see our list of games similar to Defend Your Life: TD.

Adventure Academia: The Fractured Continent is a fully-fledged strategy RPG set in the world of Class of Heroes! Create your own party of students in a fantasy realm! Pick them up and guide them to victory against the monster hordes! If you enjoyed this game, see our list of games similar to Adventure Academia: The Fractured Continent.

40%Game Brain Score

Most mentioned positive aspects:graphics

Most mentioned negative aspects:gameplay, stability

52% User Score Based on 29 reviews

Multicellular will take you back in time, to the dawn of life. Build your multicellular organism and combat hunger, the environment, darkness and other organisms. Everything in this new world can kill you, will you be able to survive? If you enjoyed this game, see our list of games similar to Multicellular.

You wake up again—your bones soaked in blood. Demo Available NOW! Play the free demo and get a SMALL BLOODY SLICE of the gameplay! Full Release – December 15 The FULL roguelike experience, with constant and explosive progression: including TONS of enemy types, abilities, weapons, and rooms. Prepare to dive into the full story—an intertwined experie… If you enjoyed this game, see our list of games similar to Heart of Bone.

A roguelite tower defense game where you protect your body from invading germs. Draft turret cards, build strong defenses, and supply them with blood to protect your heart. Fight through 10 organs and evolve your immune system between runs. If you enjoyed this game, see our list of games similar to Get Outta My Gut.

Leaf is a single-player 2.5D top-down roguelite shooter by a young team. After 200 years of slumber, the protagonist braves danger to reunite with their child. Explore random maps, craft builds with weapons and skills, select chests for progression, and keep trying with permanent talents. If you enjoyed this game, see our list of games similar to LEAF.

At the twilight of the apocalypse, will you be a Zombie Herder, or humanity's Savior?In a crowd, those who stand apart often invite envy or jealousy; those who are stronger may find themselves demanded of even more. Even seclusion in mountain forests cannot sever the world's shackles completely. Ten years ago, a biochemical virus swept across the globe. Though humanity fought back with all its mi… If you enjoyed this game, see our list of games similar to Zombie Self-Cultivation.

Protect your kingdom in a game that combines Tower Defense and Action RPG. Build your perfect defense with towers, skills, hero, upgrades, and research to face 200+ different enemies. Evolve your hero, unlock new abilities, and expand your inventory to prepare for the greatest challenges! If you enjoyed this game, see our list of games similar to King Rooster TD (Rei Galo TD).

In this charming and bloody Roguelite, you Shoot your way through hordes of Mutant Rats, Defeat Bosses and Rescue cats to bolster the Feline Resistance! Crawl through sewers, cities and laboratories. Unlock weapons, upgrades and perks to help the cats survive in this dystopian world. If you enjoyed this game, see our list of games similar to Catlite.

In the shadows, a light has risen, her name: Booby. Against the grip of tumors, where coldness, pain, and solitude reign, she does not back down. Driven by love and friendship, she fights through the darkness of cancer, turning despair into hope. A fast-paced, intense rogueliteBoobyRogue: Tumor Takedown is a 2D single-player roguelike, fast and demanding, where every run is a unique adventure. Yo… If you enjoyed this game, see our list of games similar to BoobyRogue: Tumor Takedown.

Set up camp deep in the heart of the jungle and get ready for a true adventure! Explore forgotten ruins, collect ancient artifacts, upgrade your gear, and expand your expedition camp. In Jungle Jinx, you choose your path: dodge deadly traps, battle enemies, or race through wild jungle tracks in chaotic kart runs! Your base and control center for all adventures. Upgrade buildings, enhance weapons,… If you enjoyed this game, see our list of games similar to Jungle Jinx.

Ready for some chaos? Command 5 characters in this Roguelite Tower Defense! Build your dream team, crush enemies, and have a blast with adorable pixel art! If you enjoyed this game, see our list of games similar to Mayhem Maidens.

THE GRAND PLAN BACKFIRED. World leaders and the scientists serving them aimed to reduce humanity under the guise of "population control." But there was one variable they didn't calculate: The dead didn't go quietly. They came back. When billions of corpses rose again with an insatiable hunger, kingdoms fell, armies collapsed, and the world was buried in dark ash. Outside, there is only … If you enjoyed this game, see our list of games similar to Zombi Efem.

游戏概述《史小坑的黑暗料理》是一款融合策略佣兵养成、秘境探索 与 黑暗料理烹饪 的奇幻冒险RPG！玩家将化身冒险队长，率领小队深入未知大陆，收集诡异食材、研发黑暗食谱，用料理赋予佣兵颠覆常理的战斗异能！从冰封雪原到熔岩火山，揭开世界背后的惊天真相！ 核心特色 黑暗料理：颠覆战局的烹饪革命 150+猎奇食谱： 辣椒果冻 → 觉醒【烈焰】异能：火球暴击烧穿敌阵！ 仙人掌葡萄酒 → 激活【土抵抗】异能：硬抗BOSS致命一击！ 盐巴泡菠萝 → 触发【木屑】暴击：每秒追加200%木属性伤害！ 元素附魔体系： 武器淬炼 火焰/水流/雷鸣附魔，普攻自带元素特效！ 属性克制链 木→土→雷→水→火→木，策略组合碾压强敌！ 深度宠物养成：繁殖+继承+战场协同 怪物牧场繁殖系统： 捕捉野外BOSS，培育 一公一母宠物交配，孵化稀有二代蛋！ 后代 继承父母技能（双技能父母必… If you enjoyed this game, see our list of games similar to 史小坑的黑暗料理.

A turn-based roguelike fusing Wild West and Cthulhu Mythos. Load custom revolver bullets to survive a wasteland of madness. Discover dozens of unique upgrades, endless combat builds, and unforgettable adventures. If you enjoyed this game, see our list of games similar to 西部枪手.

TEXTORIO You crash-land on Kepler-442b — a planet that wants you dead. 50,000 colonists sleep in cryo-pods deep below the surface. Wake them, or die trying. In Textorio, you build a factory in pure ASCII. Raw ore becomes circuits. Circuits become machines. Machines become a self-sustaining production empire — and that empire is the only thing standing between humanity and extinction on an… If you enjoyed this game, see our list of games similar to Textorio.

ARB: Alien Races Battle is a lane-based alien auto-battler where strategy, economy, positioning, and army comp determine victory. Choose from 5 unique factions, command alien races, unlock upgrades + faction doctrines, and overwhelm your opponents through superior planning, control, and adaptation. If you enjoyed this game, see our list of games similar to ARB: Alien Races Battle.

Three teenagers are transported to a cursed Halloween dimension. Use powers based on their costumes, face hordes of monsters, create powerful builds, and find the portal to return home in this frantic action roguelike. If you enjoyed this game, see our list of games similar to Arcane waves.

81%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:replayability, optimization

81% User Score Based on 73 reviews

Play as Nikolas, a 20-year-old guy who found himself lost in a completely abandoned city... or so he thought it was at first. Explore the city, defend yourself from monsters, and find answers to what is really going on. If you enjoyed this game, see our list of games similar to Pyromaniac.

Fuse elements. Evolve your weapons. Destroy the swarm. Mutant Survivors is a fast-paced roguelite bullet heaven where elemental fusion shapes your power. Combine 5 elements to create 10 devastating hybrid evolutions, defeat colossal bosses, and face Voltris. If you enjoyed this game, see our list of games similar to Mutant Survivors.

Welcome to the fantastical arena of Small Hero! This is a fast-paced, entertaining light Roguelike action survival game. You will play as a lone hero, facing off against waves of monsters. Each round is a brand-new adventure: you must shop and strengthen yourself between waves, then dive into the next, even more intense battle for survival! Will you become a crit-slashing Berserker or a sharpshoo… If you enjoyed this game, see our list of games similar to Small Hero.

96%Game Brain Score

Most mentioned positive aspects:gameplay, music

Most mentioned negative aspects:grinding, stability

96% User Score Based on 1,665 reviews

You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions. If you enjoyed this game, see our list of games similar to Pathogenic.

85%Game Brain Score

Most mentioned positive aspects:story, gameplay

100% User Score Based on 36 reviews

A game about collecting bath water in a post-apocalyptic world where water is precious. Approx. 5 minutes of playtime with 4 different endings. I fixed the problem with launching in the itch.io app(2025/09/04). New store page now live Please add it to your wishlist! https://store.steampowered.com/widget/3596670/ Released mobile games App Sto… If you enjoyed this game, see our list of games similar to MOCHI-O.

89%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:grinding, optimization

90% User Score Based on 307 reviews

Critic Score 80%Based on 1 reviews

Minos is a maze-building roguelite where you, the fabled Minotaur, must defend your sanctuary from bloodthirsty adventurers. Design and re-design deadly labyrinths, set traps, and turn every brave fool into your next victim. If you enjoyed this game, see our list of games similar to MINOS.

56%Game Brain Score

Most mentioned positive aspects:graphics, replayability

Most mentioned negative aspects:gameplay, grinding

78% User Score Based on 23 reviews

Roadmap About the GameThe Continent has fallen. The Invasion is here. You are the city of Belrak’s last hope of survival!  The Gate Must Stand is a medieval fantasy roguelike tower defense game that puts you in the thick of the action! Choose your valiant warrior, recruit your allies, upgrade their skills, and discover powerful synergies to hold the last line of defense.  Remember: heroes … If you enjoyed this game, see our list of games similar to The Gate Must Stand.

"Slime Survivors" – Survive the Limitless Monster Onslaught!As endless hordes of demons swarm like tidal waves, you’ll become a hero of the Slime Kingdom, upgrading diverse weapons to forge instruments of carnage! Dodge through bullet-hell barrages, unleash dazzling ultimate skills to shred enemy waves, and experience an adrenaline-pumping roguelike survival frenzy! How to PlayAll you… If you enjoyed this game, see our list of games similar to Slime Survivors.

Defend the last bastion of humanity with magic and strategy in this intense tower defense game. If you enjoyed this game, see our list of games similar to Realm.

72%Game Brain Score

Most mentioned positive aspects:humor, music

Most mentioned negative aspects:gameplay, story

88% User Score Based on 33 reviews

The Rats are invading the forest, and you are the SPIRIT OF VENGEANCE! Your objective is simple: EXPLORE the valley, EXPLOIT its resources, EXPAND your village, and EXTERMINATE the endless horde of Rats! You are a powerful Spirit of Vengeance, capable of cutting down thousands of Rats with your magical powers. But you cannot do this alone: you will need to harvest resources to construct buildings … If you enjoyed this game, see our list of games similar to Kill A Million Rats.

95%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:grinding, music

95% User Score Based on 577 reviews

An RTS-Roguelike hybrid with auto-battling troops. Master building placement, swarm your enemies, and smash their defenses with unit-commander combos! If you enjoyed this game, see our list of games similar to There Are No Orcs.

77%Game Brain Score

Most mentioned positive aspects:gameplay, graphics

Most mentioned negative aspects:grinding, story

77% User Score Based on 166 reviews

Bioweaver is an RPG game with the main content of treasure hunting and character building. You can use basic programming logic to deeply customize your skill sets, and you can also create organs with different attributes and functions with the special crafting system. If you enjoyed this game, see our list of games similar to Bioweaver.

71%Game Brain Score

Most mentioned positive aspects:gameplay, story

Most mentioned negative aspects:replayability, graphics

71% User Score Based on 58 reviews

Bullet heaven, deckbuilding, and strategy – Moon Watch is a wild new mix from the creators of Backpack Hero! Master your tactics, not reflexes: stop time at will, craft a killer deck, stop the horde in their tracks! If you enjoyed this game, see our list of games similar to Moon Watch.

94%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:grinding, optimization

94% User Score Based on 880 reviews

Primordialis is a physics-based roguelike fish builder. Unleash your creativity to defeat creatures using venomous tentacles, electrical shocks, or exploding children. The possibilities are endless. Explore the primordial depths to reveal its secrets and discover what lies beyond. CreateThe core of Primordialis is its simple yet deep creature creation system. Your body is constructed out of cells … If you enjoyed this game, see our list of games similar to Primordialis.

90%Game Brain Score

Most mentioned positive aspects:gameplay, replayability

Most mentioned negative aspects:graphics, story

90% User Score Based on 60 reviews

Wishlist On Steam! Survive the treacherous sea in this quirky multiplayer shooter game! Play solo or team up and fight off Cthulu's minions. Master a unique recoil-based mechanic to blast enemies and chart your course. Mix and match upgrades to craft the perfect sea-surviving strategy! Recoil-Driven Navigation Propel yourself through the waters with each shot! Turn gunplay into a dance of str… If you enjoyed this game, see our list of games similar to Bang Bang Barrage.

85%Game Brain Score

Most mentioned positive aspects:story, gameplay

Most mentioned negative aspects:grinding, replayability

85% User Score Based on 189 reviews

Space Prison is a tactical survival game with turn-based brawls & RPG-social mechanics. Survive the galaxy's toughest prison and rise to the top of a gang! Explore, fight, befriend, trade & craft to escape, but don't let the system break you, as death is not an excuse for a shorter sentence! If you enjoyed this game, see our list of games similar to Space Prison.

97%Game Brain Score

Most mentioned positive aspects:music, gameplay

Most mentioned negative aspects:graphics, story

97% User Score Based on 70 reviews

Pest Apocalypse is a pizza delivery action rogue-lite where you deliver cheesy hot slices to hungry wastelanders. Boost, jump, and drift across different maps in a bouncy physics-based pizza van. Pick up kooky passengers along the way and focus on the driving while they handle the shooting! Do YOU like pizza? Do YOU hate monsters? Then YOU are the only hope for the hungry wastelanders! Deliver p… If you enjoyed this game, see our list of games similar to Pest Apocalypse.