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"Chromosome Evil" is a real-time strategy horror game with squad-based controls and tactical management. Build your team with soldiers, engineers, and medics, each with unique abilities for combat and survival. Inspired by Lovecraft, the story features an ancient evil's return, unleashing nightmarish creatures and reanimating the dead. Choose your locations, equipment, skills, and strategies in this dark, suspenseful RTS.

Chromosome Evil screenshot
Chromosome Evil screenshot
Chromosome Evil screenshot
Chromosome Evil screenshot
Chromosome Evil screenshot
Chromosome Evil screenshot

87%
Audience ScoreBased on 414 reviews
story26 positive mentions
grinding8 negative mentions

  • The game offers a unique blend of RTS, RPG, and horror elements, providing a challenging and engaging experience.
  • The atmosphere and graphics are well-received, with many players appreciating the nostalgic feel reminiscent of classic flash games.
  • The developers are responsive to community feedback and actively work on improving the game, which enhances player trust and engagement.
  • The controls and UI are often criticized for being clunky and unintuitive, leading to frustrating gameplay experiences.
  • The save system requires in-game resources, which can be punishing and lead to significant loss of progress if the game crashes.
  • Many players report issues with difficulty balancing, feeling that the game can be excessively punishing, especially for new players.
  • story
    144 mentions Positive Neutral Negative

    The game's story is generally described as simple and somewhat generic, with a few engaging elements and branching paths that allow for multiple playthroughs. While some players appreciate the risk-reward scenarios and the atmosphere, others criticize the writing quality and the linearity of the main missions. Overall, the narrative provides a decent backdrop for the gameplay, but it may not be compelling enough to sustain interest over extended sessions.

    • “The atmosphere and depletion of resources work together to really sell the vibe of the story and setting.”
    • “Also, multiple endings, various things you think on your 2nd/3rd time through to try differently, 3 different storylines with the branch starting early so you do get a multitude of unique mission variety later in the game.”
    • “The long awaited successor to Flesh Eaters has come and it brings more content than its predecessor with greatly improved player choice at the main story points, during missions, or what places you pick that can change each playthrough so you can spend lots of time playing this game.”
    • “The story-telling is decent, though there are certainly some scenarios in the beginning that feel pointless.”
    • “The static, main story is just not good enough to justify multiple playthroughs.”
    • “The story is passable, writing is not great, but I'm also pretty sure neither of these guys went to school for writing, so I'll give that a pass too.”
  • gameplay
    120 mentions Positive Neutral Negative

    The gameplay is a blend of real-time strategy and RPG elements, featuring squad-based tactics, resource management, and a unique extraction mechanic, which creates an engaging and atmospheric experience. However, players have noted significant issues with basic mechanics, such as weapon selection limitations and repetitive gameplay loops across similar maps, which can detract from the overall enjoyment. Despite these flaws, many find the gameplay challenging and rewarding, with a satisfying core loop that encourages tactical decision-making and character customization.

    • “While the game style looks simple, the game itself isn't that easy. Other than the RTS gameplay as advertised, it has some RPG elements, resource management, and a little bit of that extraction mechanic like something from Escape from Tarkov or Zero Sievert. It's fun; the devs really created something that's enjoyable and atmospheric from all those ideas and components.”
    • “The gameplay loop is very fun and doesn't get boring as there is a lot of customization for each character, different maps, and a lot of choices to make.”
    • “Gameplay and atmosphere are amazing, and it's certainly something you need to try.”
    • “There is very little variety in the gameplay; all the maps and encounters are the same, and you will be going through 90% of the same gameplay loop every time you play.”
    • “This game has double limitations on gameplay.”
    • “I found the game to be slow, boring, and lacking any interesting features or mechanics that I wanted to explore.”
  • atmosphere
    30 mentions Positive Neutral Negative

    The atmosphere of "Chromosome Evil" is widely praised for its immersive and tense qualities, effectively blending elements of survival horror and tactical gameplay. Reviewers highlight its successful integration of resource management and RPG mechanics, creating a compelling post-apocalyptic vibe reminiscent of classic titles like X-COM and Darkwood. Despite some technical issues, the overall ambiance and nostalgic feel contribute to a highly engaging experience.

    • “The atmosphere and depletion of resources work together to really sell the vibe of the story and setting.”
    • “Great post-apocalyptic atmosphere and gameplay!”
    • “Chromosome Evil is a fine blend of the oppressive atmosphere of Darkwood, the challenging difficulty of X-COM: TFTD, and just a dash of Jagged Alliance squad command and management.”
    • “For me, Chromosome Evil gets closer to the atmosphere of the original X-COM than some of the newer entries in the franchise did, and it does so by changing up its core mechanics.”
    • “I just love how in tune it is with the whole atmosphere.”
  • graphics
    18 mentions Positive Neutral Negative

    Overall, the graphics of the game receive positive feedback for their art style and atmosphere, contributing to a solid replay value. However, some users noted issues such as graphical bugs in specific maps and a lack of variety in character designs. While the visuals are generally appreciated, there are suggestions for improvements in clarity and detail, particularly regarding certain effects and item descriptions.

    • “I love the vibe and art style; it's pretty solid with replay value on top.”
    • “This game has a lot going for it, from the art style to the gameplay.”
    • “Great game, I really like the atmosphere and the graphics.”
    • “One of the marketplace maps in the residential area seems to have bugged graphics and displays black squares over the ground.”
    • “Some things that I feel need improvement are better descriptions of items and upgrades, some better visuals (some fire, such as that from explosive barrels, can be a bit difficult to see, for example), better PC pathfinding (PCs will actively walk through hazards even if there's a safe path they can take), and some variety in character portraits since most are just the same guy but with different hair/helmet and facial expressions.”
    • “While players who enjoyed flesh-eaters will enjoy this game, those who might have been hoping for more out of Chromosome Evil aside from aesthetic changes may end up feeling that not much has changed.”
  • replayability
    14 mentions Positive Neutral Negative

    The game is praised for its high replayability, offering numerous choices and multiple endings that encourage players to engage in multiple playthroughs. While some users noted a lack of character customization that could enhance variety, the overall experience remains enjoyable and challenging, with many players reporting the potential for extensive gameplay without repeating the same experience.

    • “The game is relatively cheap, highly replayable, gives a challenge to the player, and encourages multiple playthroughs due to many choices and endings.”
    • “This game has so much replayability that you could play for 50 hours and still not have the same playthrough once.”
    • “A bit low on customization and replayability, and definitely could use a bit more polish, but loved the game anyway.”
    • “You can't customize your starting character equipment (only shotgun, pistol, and fist). It would be nice if you could customize your starting character equipment through points (like the trait points from Project Zomboid, only for equipment). If the starting characters had different equipment, then every run would have more replayability and variety.”
    • “Multiple endings and moral choices also affect the replayability.”
  • music
    14 mentions Positive Neutral Negative

    The music in the game has received mixed reviews; while some players appreciate the ambient sounds and subtle soundtrack, others criticize the repetitive nature of the tracks, feeling that it detracts from the overall experience. There are mentions of the music being well-composed but lacking variety, particularly for a Lovecraftian-themed game, leading to a sense of missed potential. Additionally, some users noted the use of music from other games, which raises concerns about originality.

    • “The ambient noises work well with the game as well as the subtle but nicely done soundtrack.”
    • “I also want to point out how great the music is in this game.”
    • “Like an RTS mixed with Fallout/Stalker system to mix things up, can't say enough good things about it plus the music.”
    • “There's potential here for a fun rogue-like RTS, but it's held back by a horrendous UI, poor controls, and a grating soundtrack.”
    • “A great example of this game being done on the cheap is the main music from the game Hostage Negotiator on the iOS App Store being used in this game!”
    • “The soundtrack is so grating that it detracts from the overall experience.”
  • grinding
    10 mentions Positive Neutral Negative

    Players find the grinding aspect of the game to be tedious and frustrating, often feeling that the rush to progress is undermined by the slow pace of loot collection and farming. While some exploits can alleviate the grind, the overall experience is described as requiring excessive time and effort, leading to a sense of monotony.

    • “It's tedious and frustrating.”
    • “That's fine... but the game undermines itself by making this 'rush rush rush' playstyle actually feel slow and tedious.”
    • “You'll need a second life for grinding.”
  • humor
    8 mentions Positive Neutral Negative

    The humor in the game is polarizing; some players find certain elements amusing, such as the inability to close doors, while others feel that the challenges, particularly in hive fights, are frustrating rather than funny. Overall, the comedic aspects seem to be overshadowed by gameplay difficulties, leading to mixed reactions among users.

    • “And you can't close the door once you open them... huh... very funny.”
    • “Looking forward to any future content the dev brings and still laughing that they added a trainer/cheats themselves.”
    • “And some of the hive fights are so overpowered it's not even funny that you need a max party and an obscene amount of ammo to deal with dozens of giant worms being spawned and thrown at you every couple of seconds.”
    • “Oh come on, this is not funny!”
    • “Oh come on, this is not funny!”
  • stability
    6 mentions Positive Neutral Negative

    The game currently suffers from stability issues, including a buggy interface and translation errors, which can disrupt gameplay, such as characters being deselected when changing weapons. However, the small development team is noted for their responsiveness and commitment to addressing these problems, suggesting improvements may be forthcoming.

    • “The interface is a bit buggy, with characters frequently being deselected when you click to change weapons.”
    • “The game is fairly buggy and has some translation issues, but the devs (a team of two I believe) are very responsive and seem to work very diligently to fix them, so I imagine that won't be an issue soon.”
    • “Misspelled instructions, bad interface, buggy mess...”
  • optimization
    2 mentions Positive Neutral Negative

    The optimization of the game is widely criticized, with many users likening its performance to that of an early alpha version rather than a polished, completed product. This suggests significant issues that detract from the overall gaming experience.

    • “It feels like a really early access game in terms of performance, like early alpha, not a completed game.”

Buy Chromosome Evil

6h Median play time
6h Average play time
6-6h Spent by most gamers
*Based on 2 analyzed playthroughs

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