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Games like The Last Leukocyte: Immune Protocol

Games like The Last Leukocyte: Immune Protocol

Games like The Last Leukocyte: Immune Protocol

Looking for games like The Last Leukocyte: Immune Protocol? Here are top casual hack and slash recommendations, selected from player-similarity data — start with Yokai Survivor, Where Giants Fall or Football Survivors.

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  1. Yokai Survivor is a single-player survivor-like auto-shooter. Face relentless waves of twisted yokai in a cursed underworld, harvest precious fruits, and master powerful ninjutsu skills to turn the tide. Grow stronger with each run, unlock deadly abilities, and carve your path through the darkness. It’s one ninja against a world of nightmares — how long can you survive? Key Features ⚔️ Survive… If you enjoyed this game, see our list of games similar to Yokai Survivor.

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  2. Survive, upgrade, become unstoppable Where Giants Fall is a 3D top-down fantasy bullet-heaven action roguelite with survivors-like build growth, movement-first combat, and the thrill of turning a fragile run into overwhelming power. Every run takes you through regular stages, objective-driven Ritual Sieges, boss-biome encounters, and an Endless Mode finale. Auto-fire weapons keep the pressure … If you enjoyed this game, see our list of games similar to Where Giants Fall.

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  3. Angry Fans Storm the Pitch. Defend Your Stadium, Command Your Own Security Team!Take control of characters from different professions, position them strategically, and grow stronger with each wave as you hold off endless hordes of furious fans. Make the right choices in a chaotic football roguelike experience — build your defenses and drive the stands back! Strategic Placement: Deploy your heroe… If you enjoyed this game, see our list of games similar to Football Survivors.

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  4. FIGHT BY DAY. CHOOSE BY NIGHT.Cruzado blends fast-paced action with strategic decision-making. During the day, you must survive relentless hordes of enemies. Make it through the battle, and nightfall gives you a chance to recover your health, drink potions, improve your equipment, and prepare for the next day. But every decision you make at night comes at a cost. You only have a limited number of… If you enjoyed this game, see our list of games similar to Cruzado.

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  5. BUILD THE MACHINE. TAKE THE LOOT. EARN THE EXIT.Core Reset is a single-player bullet-hell mech survivor extraction-looter built around one question: how much are you willing to risk before you call the dropship? Assemble a mech from salvaged parts, choose your route across a hostile sector, and deploy into combat missions filled with swarms, strongholds, objectives, and battlefield loot. When y… If you enjoyed this game, see our list of games similar to Core Reset.

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  6. ⚠ CONTAINMENT FAILURE IMMINENT A Tactical Sci-Fi Horde Survival Roguelike where every strategic choice matters. Suppress a rapidly evolving biological outbreak consuming a fallen military research complex. Fight alongside HELIOS, a damaged tactical AI whose forecasts grow less reliable with every passing Dawn. Deploy orbital defenses, fuse experimental technologies, engineer devastating weapon b… If you enjoyed this game, see our list of games similar to Deep Breach.

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  7. Too Many CUBES! Too Many CUBES! is a fast-paced arena-survival roguelike where every run begins with one small cube and ends in a storm of lasers, mines, orbiters, ricochets, gravity wells, and shattered geometry. Move and aim while your weapons fire automatically. Collect experience, choose your upgrades, and assemble a build powerful enough to survive increasingly overwhelming swarms. … If you enjoyed this game, see our list of games similar to Too Many CUBES!.

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  8. Command. Survive. Evolve.You are the last Biocore Pilot — a survivor stranded on a dying alien world. Your only hope lies within the Biocore system, an ancient technology capable of creating life, weapons, and power beyond human understanding. But every pulse of energy draws swarms of hostile creatures closer. Survive long enough to rebuild, upgrade, and uncover what remains of humanity’s final ou… If you enjoyed this game, see our list of games similar to Core Remnants.

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  9. Recruit. Merge. Mow Down Endless Hordes. Welcome Back to Work is a fast-paced survivors-like action roguelite set inside a corporate apocalypse. One bathroom break was all it took. Now the office has become an endless death loop. Stationery has turned hostile, mutant plants have swallowed the building, and swarms of grotesque office creatures fill every floor. Build your team, create unstoppab… If you enjoyed this game, see our list of games similar to 欢迎继续上班 (Welcome Back to Work).

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  10. BOOT THE CARTRIDGE. CHOOSE YOUR PARTNER. DO NOT EJECT.Do Not Eject is a retro handheld-inspired bullet heaven roguelite where corrupted game cartridges have trapped living digital creatures inside. Choose your partner, insert a cartridge, and fight through waves of corrupted programs as your attacks evolve from a handful of projectiles into ridiculous combinations of ricochets, orbiting weapons, … If you enjoyed this game, see our list of games similar to Do Not Eject.

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  11. Save Your Kingdom. Survive the Chaos.Face thousands of monsters in a fast-paced pixel art action roguelite. Can you endure the unforgiving landscapes and the deadly creatures that roam them Find out in this intense and endlessly replayable adventure. Features Earn experience quickly as you battle through endless waves of enemies Unlock new and powerful skills as your character levels up F… If you enjoyed this game, see our list of games similar to Medieval Chaos.

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  12. Build VarietyEvery stage arms you with a new set of tools. Stack, synergize, and push your upgrades to the absolute limit to create BROKEN builds. Experimentation is your best weapon. You will probably fall, but losing is just part of the process. Learn the enemy patterns, tweak your strategies and push further on the next run. Choose Between 2 Challenging Play ModesWhether you prefer deliberat… If you enjoyed this game, see our list of games similar to Echoes of Kyria.

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  13. 60%Game Brain Score
    Most mentioned positive aspects:gameplay
    Most mentioned negative aspects:graphics
    100% User Score Based on 11 reviews

    King Charles is a fast-paced, dog-powered survival action game where every minute matters. Dodge relentless swarms, collect XP and gold, and build a devastating loadout through quick card choices and permanent upgrades. The longer you survive, the more intense the hunt becomes—especially when miniboss waves start arriving. How it playsYou fight automatically while you focus on movement, positioni… If you enjoyed this game, see our list of games similar to King Charles: Rise of the Alpha.

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  14. 35%Game Brain Score
    Most mentioned negative aspects:gameplay, graphics
    60% User Score Based on 10 reviews

    Our Discord- - *Wild Legion es parte de Erabit's Bud Scheme, un espacio para la creatividad de juegos y desarrolladores en solitario/equipos pequeños para prosperar. If you enjoyed this game, see our list of games similar to Wild Legion.

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  15. AN ACTIVE INCREMENTAL TOWER DEFENSEHow to Turn Zombie combines incremental progression, tower defense pressure, and direct cursor-based combat. Attack cells directly with your cursor Defend your central Viral Core Harvest Biomass and unlock permanent mutations Build powerful upgrade synergies Adapt to new mechanics across different organs Face increasingly dangerous immune defenses and… If you enjoyed this game, see our list of games similar to How to Turn Zombie.

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  16. Survivors-Like Combat, Hack-and-Slash Builds Looter Survivors takes the immediate, swarm-clearing action of a survivors-like game and adds the buildcraft of a hack-and-slash loot game. Your power does not come only from leveling up during a run. It comes from the gear you collect, the random effects attached to that gear, and the way those effects shape your next build. Find equipment, comp… If you enjoyed this game, see our list of games similar to Looter Survivors.

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  17. Luxmithar is a 2D survival defense roguelite built in Godot, where you defend a crashed forge-ship against escalating waves of hostile forces. Each run unfolds across multiple days as you harvest resources, expand a modular grid-based world, and construct layered defenses to hold back relentless alien incursions. If you enjoyed this game, see our list of games similar to Luxmithar.

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  18. Surviving is not enough. Fight to stay alive as relentless alien swarms take over a hostile world. Lost Galaxy: Survivors is a fast-paced sci-fi top-down survival shooter where every run is about adapting, building your power, and pushing as far as you can before being overwhelmed. Level up in real time and choose upgrades that shape your build—boost your weapons, enhance your mobility, unlock … If you enjoyed this game, see our list of games similar to Lost Galaxy: Survivors.

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  19. Gladiator's Arena is a top-down arena shooter rogue-lite where you play as a gladiator wielding up to 7 different medieval weapons to fight off hordes of enemies. Choose from a variety of upgrades and abilities to create unique builds. If you enjoyed this game, see our list of games similar to Gladiator's Arena.

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  20. A universe is dying. You are its last spark. The constellations have gone dark, devoured by entropy. Dive into each dead world, collect the star fragments that still glow, and relight the sky — before your own light fades. Every run is a new sky Fast, readable top-down action — dash through swarms, dodge projectile storms, strike back. Pure arcade feel, no filler. Procedurally gener… If you enjoyed this game, see our list of games similar to NOVAE: Last Light.

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  21. ✅ NGC-404 is for you if you: Enjoy space strategy games with economy, fleets, colonies, and faction conflict Like games where logistics, fuel and supplies matter Want real-time 2D space battles with ship fitting and weapon control Enjoy sandbox campaigns Like managing a small fleet instead of controlling hundreds of units directly Want to explore unknown systems, survey planets, and reco… If you enjoyed this game, see our list of games similar to NGC-404: Fractured Sector.

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  22. Choose three heroes and venture out on dangerous quests. You'll be balancing battling with dodging, all while managing your party's stamina levels to ensure they can stay in the fight! Each run will take you through numerous areas while you build up your party with stat points, skills, and powerful items. With a wide cast of heroes, a boat load of monsters, and a trove of items, each run will be … If you enjoyed this game, see our list of games similar to Triple Swap Tower.

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  23. One Game, Two Ways to Face the Abyss Invasion of the Abyss is a colorful low-poly single-player game with two distinct modes that can be played independently. - Invasion of the Abyss is an action-survival mode built around hero combat, real-time progression, and descending through consecutive floors. - Abyss Survival is a tower-defense survival mode focused on construction, resource planning, a… If you enjoyed this game, see our list of games similar to Invasion of the Abyss.

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  24. Waves of ChaosDefend your lands from three ruthless kings and their invading armies. Endless waves of enemies are marching across your swamps, and only you can stop them. In Waves of Chaos, your goal is simple: survive. Face increasingly difficult waves of enemies, defeat powerful bosses, and push back the invasion before it overwhelms you. Your main weapon is magic. Enchanted items automatica… If you enjoyed this game, see our list of games similar to Waves of Chaos.

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  25. 41%Game Brain Score
    Most mentioned positive aspects:humor, graphics
    Most mentioned negative aspects:gameplay, story
    70% User Score Based on 10 reviews

    Space Bross is a thrilling blend of action 2.5D roguelite, and Tower Defense genres. You’re a retired astronaut. You had one job: chill. But then they came for your chicken. Now it’s personal. Set off on a chaotic journey across deep space in Space Bross, a roguelite tower defense action game where survival means lasers, loot, and a whole lot of clucking vengeance. Explore dangerous, ev… If you enjoyed this game, see our list of games similar to Space Bross.

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  26. Balance light and darkness in a relentless roguelite survival. Fight through chaotic waves, evolve your build, and reclaim corrupted realms. Every run pushes the balance further… will you restore the light or embrace the dark? Core Features Fast-paced 15-minute survival runs Dual progression system: Light & Dark upgrades Build-defining choices every level Unique bosses at critical milestones Multi… If you enjoyed this game, see our list of games similar to Torch of Shadows.

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  27. 77%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding, optimization
    77% User Score Based on 1,398 reviews

    FatalZone is an auto shooter with roguelike and RPG elements set in a savage world of zombies. Exterminate zombie hordes, collect resources, upgrade your camp, and level up mercenaries. Humanity must survive at any cost! If you enjoyed this game, see our list of games similar to FatalZone.

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  28. Survive together. Grow stronger forever.Endless Bonds is a top-down survival action game where one run can turn a simple weapon into a screen-clearing build. Create your survivor, choose a starting weapon and companion creature, then face escalating hordes, elite threats, and giant bosses across distinct stages. Play solo or join others in local, LAN, peer-to-peer, and online co-op. Share the fig… If you enjoyed this game, see our list of games similar to Endless Bonds.

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  29. About This GameEnter a cursed world where survival alone is not enough. Unhallowed Survivors is a dark fantasy bullet heaven roguelite built around distinct heroes, signature weapons, escalating hordes and dangerous choices. Choose your hero and enter corrupted battlefields filled with cultists, restless dead and twisted creatures. Move manually while your hero attacks automatically, collect exp… If you enjoyed this game, see our list of games similar to Unhallowed Survivors.

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  30. Every bubble holds a reward—and a new threat.Bubblecore: Survivors is an endless single-player tower defense roguelite where you decide when the next attack begins. A mysterious world of resource-filled bubbles surrounds the Citadel. Pop one to instantly claim wood, stone, food, ether, or another valuable reward. But beware: every bubble also releases a group of monsters that immediately advances… If you enjoyed this game, see our list of games similar to Bubblecore: Survivors.

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  31. Pilot an immune-cell sentinel in a neon pixel-art horde-survival auto-shooter. Move manually, auto-fire evolving weapons, draft upgrades, equip symbiotes, and survive escalating pathogen swarms inside a collapsing biotech system. If you enjoyed this game, see our list of games similar to Immunity Protocol.

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  32. A fast-paced sci-fi action roguelite where you battle escalating enemy waves, combine powerful abilities, and take on challenging boss encounters. If you enjoyed this game, see our list of games similar to Aetheris Core.

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  33. Core of Havoc is a single-player, real-time 2D space combat experience that combines tight ship controls with deep, affix-driven itemization. Set in a sleek, stylized sci-fi universe, you pilot a modular ship through procedurally generated missions where every decision—from the parts you equip to the way you maneuver—defines your path to survival. KEY FEATURES Expressive Ship Customizatio… If you enjoyed this game, see our list of games similar to Core Of Havoc.

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  34. You are the last salvager. Pilot your ship into hostile sectors, recover what others left behind, and fight your way back to the Forge before everything is lost. Starforge Reborn is a gritty top-down 2D action roguelite built around high-pressure combat, salvage-driven progression, permanent upgrades, and difficult risk-reward decisions. Push deeper into collapsing space, extract with your haul… If you enjoyed this game, see our list of games similar to Starforge Reborn.

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  35. About This GameASHES OF THE BELT is a top-down space shooter built around fast runs, heavy firepower, and satisfying progression—without the usual friction. There’s no inventory management, and you don’t lose your run rewards if you die or decide to end a run early. Jump in, fight, collect, upgrade, and push further each time. You’ll battle across space and planet surfaces, harvesting resources f… If you enjoyed this game, see our list of games similar to Ashes of the Belt.

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  36. Auto Shooter + Inventory Management This game is for people that enjoy the high octane onslaught of autoshooters, but would like more involved gameplay mechanics and a higher skill ceiling. In Zombie Survivors: Inventory Apocalypse, you must show that you have what it takes to survive the endless waves of enemies closing in, while periodically managing your backpack and weapons belt to keep up as… If you enjoyed this game, see our list of games similar to Zombie Survivors: Inventory Apocalypse.

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  37. Build a flying fortress and defend it from every direction.HEXSTORM: Tears of Arcadia is a tactical tower defense with a roguelite structure where you command the flying fortress Arcadia and build a unified combat network of turrets, support modules, and resource collectors around it. This is not a tower defense about fixed paths and passive waiting. The battlefield evolves with you. Enemies atta… If you enjoyed this game, see our list of games similar to HEXSTORM: Tears of Arcadia.

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  38. ENDURE THE ABYSS. BUILD THE SQUAD. TURN HELL AGAINST ITSELF. Hellrifters is a physics-driven squad roguelite where you start alone against the horde and grow into a four-soldier death machine. Push through escalating Rifts in the Campaign, or fight wave-based battles in the Arena. Both modes share full progression, so every unlock and upgrade carries across. Fight through grotesque demon-i… If you enjoyed this game, see our list of games similar to Hellrifters.

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  39. STELA BOSS is a roguelike that combines intense action and strategic exploration in a dark, mysterious world. Use unique elemental weapons to defeat enemies and clear the island infested with dangers in each cycle. FIGHT TO DEFEAT THE BOSSES Face hordes of enemies and imposing bosses as you explore a macabre island. Each battle is an opportunity to grow stronger and get closer to victory. DI… If you enjoyed this game, see our list of games similar to STELA BOSS.

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  40. Gloomvex is a dark sci-fi arena roguelite about surviving relentless enemy waves on a hostile alien world. Fight your way through increasingly dangerous runs, collect gold and experience, unlock upgrades, and shape your build with weapons, stats, and powerful augments. Each run pushes you to adapt quickly, improve your damage output, manage movement, and survive against growing swarms of enemies … If you enjoyed this game, see our list of games similar to Gloomvex.

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  41. Hold the Line in Deep Space A hostile fleet is closing in on your station from every direction. As the last defensive core on the frontier, you must repel waves of drones, assault craft, carriers, and siege warships before they tear through your defenses. Build a Deadly Defense Network Arm your station with a growing arsenal of futuristic weapons, each with a distinct combat role: Mi… If you enjoyed this game, see our list of games similar to STELLAR BASTION.

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  42. 83%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:grinding
    100% User Score Based on 34 reviews

    Future Plan About the GameA strange acid rain carrying an unknown virus fell for seven days and seven nights. Humanity vanished. The cities fell. The dead began to walk. But the animals survived. And some of them evolved. Now, as one of the few intelligent survivors left in the wasteland, you'll fight to protect civilization's final hope: an unfinished rocket project capable of ending th… If you enjoyed this game, see our list of games similar to Keep Her Safe.

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  43. 91%Game Brain Score
    Most mentioned positive aspects:gameplay, replayability
    Most mentioned negative aspects:optimization, graphics
    91% User Score Based on 130 reviews

    Forge a single starcraft into a fleet-leveling warship through the combination of salvaged weaponry and strategy-defining augmentations in this sci-fi survivors game! Weave through asteroid fields, aid galactic denizens, and use collected resources from each failed expedition to become permanently stronger! Your goal is survival; your legacy is inevitable. Features Intense Bullet-Heaven Combat - O… If you enjoyed this game, see our list of games similar to Starforged Legacy.

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  44. A Cozy and Chaotic Garden Defense Adventure. Welcome to Halliwell's Garden, a vibrant and ever-changing paradise where beauty and danger bloom side by side! Tend to your land by day: build charming cottages, plant bountiful crops, raise helpful animals, and nurture mystical flowers. But beware when the night falls, for your garden's allure attracts relentless hordes of monsters! Cultivate Y… If you enjoyed this game, see our list of games similar to Halliwell's Garden.

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  45. "EggsNeverHurt" is a light rogue survival game that features single-player control with dual joysticks operating two characters simultaneously. Within a limited battlefield space, your primary focus is to ensure that the non-attacking character (Little Egg) does not die, while controlling the attacking character (Big Egg) to kill enemies as much as possible. This allows Little Egg to obt… If you enjoyed this game, see our list of games similar to EggsNeverHurt.

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  46. Complete global quests to expand your selection of playable characters, each featuring a distinct playstyle and a loyal pet companion.  Objective-Based Progress: Unlock new survivors and weapons by completing specific Quests.  Hero-Pet Synergy: Every character enters the arena with a unique pet that provides dedicated support and combat assistance. Cycle through weapons, spells, passives,… If you enjoyed this game, see our list of games similar to Slime Attack: Survivor.

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  47. 86%Game Brain Score
    Most mentioned positive aspects:gameplay, emotional
    Most mentioned negative aspects:graphics, music
    86% User Score Based on 96 reviews

    Defend your Chrysalis from growing hordes of monsters in this hybrid game that combines elements of tower defense, survival, and roguelike RPGs. Explore procedurally generated levels, possess and control animals, and grow deadly gardens. How far can you get before the next wave of monsters attacks? In Chrysalis, you play the role of an incorporeal Wisp tasked with defending a magical Chrysalis fr… If you enjoyed this game, see our list of games similar to Chrysalis.

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  48. 88%Game Brain Score
    Most mentioned positive aspects:music, graphics
    Most mentioned negative aspects:gameplay
    95% User Score Based on 43 reviews

    https://store.steampowered.com/widget/3310000/This game was originally created in 72 hours during Ludum Dare 56, in October 2024. We're currently working on an improved version, which will be released on Steam in early 2025! This version is a free demo, and we'll provide a link to the full game on Steam when it's available!  Stay tuned! Small creatures, but massive destruction! In this colorful … If you enjoyed this game, see our list of games similar to Chumini: Tiny Army.

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  49. 93%Game Brain Score
    Most mentioned positive aspects:gameplay, graphics
    Most mentioned negative aspects:story, grinding
    93% User Score Based on 92 reviews

    Humanity has angered the gods by ravaging the Earth. Now, they are punished with a colossal arena of death, where all species must fight to survive. Faced with ferocious creatures, deadly traps, and a harsh environment, can humanity redeem their mistakes and prove their worth before the cold judgment of the gods? Gameplay Become a legendary warrior: Choose your preferred character class, each with… If you enjoyed this game, see our list of games similar to Fight To The Death.

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  50. Battlethorne Survivors is a third person action roguelite survival game with a focus on companions. Massacre hordes of fantastical beasts and collect gold for unlocking powerful trinkets to take on even harder maps and Bosses. Key Features Fight thousands of fantastical beasts Over 20 Unique enemy types with their own unique attacks Over 30 Companions to Unlock Unlock hundreds of trinkets to po… If you enjoyed this game, see our list of games similar to Battlethorne: Survivors.

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