Games like Prokaryo

55%Game Brain Score

gameplay, music

graphics, grinding

55% User Score Based on 102 reviews

Take control of a determined White Blood Cell on a quest for self discovery, vengeance, punishment and annihilation of all evil germs who would dare infiltrate an unsuspecting and innocent human body in this unique and organic experience. Battle evil germs by slamming into them, using your Powerbutt ability to further enhance the damage and pain inflicted. If you enjoyed this game, see our list of games similar to Germ Wars.

Description Bacteriophage Roguelike Platformer takes place inside the body of someone with many bacterial infections. You play as a cyborg named Terri (“like bacteria”), with a gun that shoots bacteriophage DNA-infused bullets. Your job is to make your way through this human body and destroy any and all bacteria and infections that stand in your way. Features Roguelike platformerFully functioning … If you enjoyed this game, see our list of games similar to Bacteriophage.

(Download and play the .exe build for best performance) Innards Exterminator: A boss rush + action platformer game developed for the Summer 2021 Boss Rush Jam: https://itch.io/jam/boss-rush-jam-2021  A colossal, monstrous Gargantuan is threatening Earth. No country's firepower or nuclear weapons can put a dent in it's skin. The world's only hope is a mysterious biologist, who sets off on a missio… If you enjoyed this game, see our list of games similar to Innards Exterminator.

45%Game Brain Score

gameplay, graphics

71% User Score Based on 14 reviews

Systematic Immunity is a challenging precision platformer set inside the human body...and not a particularly healthy one either. This body has been infected by a big, nasty bugger of a germ, who is making it his business to spawn many more germs as fast as he can. You and your mob of 20 white blood cells must put a stop to his shenanigans at all costs! If you enjoyed this game, see our list of games similar to Systematic Immunity.

Get-A-Grip Chip and the Body Bugs sends Chip on a new mission: enter the human body and dismantle digestive distress! In this satisfying 2D platformer, master Chip’s grappling hook to get things flowing. Raise an army of white blood cells to fight off the Body Bugs as you grapple for guts and glory. If you enjoyed this game, see our list of games similar to Get-A-Grip Chip and the Body Bugs.

Defend the body in vaXinator, a fast-paced action roguelike! As the last white blood cell, unleash powerful abilities and antibodies to fight off waves of infections. Test your reflexes in this microscopic battle for survival. How long can you hold the line? If you enjoyed this game, see our list of games similar to vaXinator.

A project for Amaze Me Game Jam =background= In near furture, mankind has discover a new type of energy source. It was found that when it transform to power that we use it will emit bright colored light without generating much heat. So people start refering this new source of energy a name that they are familiar with, "NEON". As times fly by, changes also happened. Human body are reacting differe… If you enjoyed this game, see our list of games similar to A NEON night.

The Indie City Mixtape is a collection of small games made by members of Indie City Games, all contained within a single launcher. Run and jump around a 3D platforming environment and navigate to the various games contained within! Inside you'll find a llama barbershop, a family home that is not as it seems, a highly forgetful and traffic felony committing mom, and more; all made by small teams an… If you enjoyed this game, see our list of games similar to Indie City Mixtape 2026.

Game You are a swarm of alien microorganisms infiltrating the human body. You have but one goal: Complete and utter domination of the mind. In this roguelite deckbuilder, you play as infectious microbes in a struggle against the body's immune system. Duplicate cards through mitosis, gain momentum in battle, and defeat white blood cells in order take control of the frontal lobe. Source Code Th… If you enjoyed this game, see our list of games similar to Prefrontal Vortex.

You are a blood cell. Your job is to help the body survive - and not be destroyed while doing it! Wounds, viruses and mutated cells plague the body, and basic oxygen related operations have to be kept up as well. Not only that, you only have 10 seconds to complete each task! Luckily, time is relative around here - as long as you stand still, the world will slow around you.If you die (enough times … If you enjoyed this game, see our list of games similar to Microscopic Mayhem.