About Active Immunity
Active Immunity is a single player and multiplayer action game. It was developed by Dylpickle Studios and was released on October 30, 2026.
A twin-stick bullet-hell roguelite fought inside the human body. Pilot an immune cell through escalating waves of pathogens, dodge dense bullet patterns, and stack upgrades into synergies that rewrite your build. Choose how each outbreak mutates, then push a run into endless.


Games Like Active Immunity
Looking for games like Active Immunity? Here are top action recommendations, selected from player-similarity data — start with Pathogenic, Rogue Star Rescue or Aetheris Core.
Frequently Asked Questions
Active Immunity is a action game. Common tags for Active Immunity include science, indie, roguelite, 2d, bullet hell and others.
Active Immunity is available on PC, Windows and Linux.
Active Immunity was released on October 30, 2026.
Active Immunity was developed by Dylpickle Studios.
Active Immunity is a single player game with multiplayer and local co-op support.
Similar games include Pathogenic, Rogue Star Rescue, Aetheris Core, Null Drifter, DunHero and others.










